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Items: 1 to 20 of 100

1.

Renin and prorenin activate pathways implicated in organ damage in human mesangial cells independent of angiotensin II production.

Melnyk RA, Tam J, Boie Y, Kennedy BP, Percival MD.

Am J Nephrol. 2009;30(3):232-43. doi: 10.1159/000220260. Epub 2009 May 19.

PMID:
19451703
2.

Activated prorenin as a therapeutic target for diabetic nephropathy.

Ichihara A, Sakoda M, Mito-Kurauchi A, Itoh H.

Diabetes Res Clin Pract. 2008 Nov 13;82 Suppl 1:S63-6. doi: 10.1016/j.diabres.2008.09.027. Epub 2008 Oct 14. Review.

PMID:
18922597
3.

Functional renin receptors in renal mesangial cells.

Huang Y, Border WA, Noble NA.

Curr Hypertens Rep. 2007 Apr;9(2):133-9. Review.

PMID:
17442225
4.

Renin, prorenin and the kidney: a new chapter in an old saga.

Ichihara A, Sakoda M, Kurauchi-Mito A, Kaneshiro Y, Itoh H.

J Nephrol. 2009 May-Jun;22(3):306-11. Review.

PMID:
19557706
5.

Prorenin/renin receptor, signals, and therapeutic efficacy of receptor blocker in end-organ damage.

Inagami T, Ichihara A.

Curr Hypertens Rep. 2007 Dec;9(6):474-9. Review.

PMID:
18938683
6.

Role of (pro)renin receptor in cardiovascular cells from the aspect of signaling.

Hitom H, Liu G, Nishiyama A.

Front Biosci (Elite Ed). 2010 Jun 1;2:1246-9. Review.

PMID:
20515797
7.

Inhibition of renin/prorenin receptor attenuated mesangial cell proliferation and reduced associated fibrotic factor release.

He M, Zhang L, Shao Y, Wang X, Huang Y, Yao T, Lu L.

Eur J Pharmacol. 2009 Mar 15;606(1-3):155-61. doi: 10.1016/j.ejphar.2008.12.050. Epub 2009 Jan 13.

PMID:
19174157
8.

Prorenin and (pro)renin receptor: a review of available data from in vitro studies and experimental models in rodents.

Nguyen G, Danser AH.

Exp Physiol. 2008 May;93(5):557-63. doi: 10.1113/expphysiol.2007.040030. Epub 2008 Mar 30. Review.

9.

[(Pro) renin receptor].

Ichihara A, Ito H.

Nihon Rinsho. 2009 Apr;67(4):675-80. Review. Japanese.

PMID:
19348227
10.

Prorenin uptake in the heart: a prerequisite for local angiotensin generation?

Jan Danser AH, Saris JJ.

J Mol Cell Cardiol. 2002 Nov;34(11):1463-72. Review.

PMID:
12431445
11.

The biology of the (pro)renin receptor.

Nguyen G, Muller DN.

J Am Soc Nephrol. 2010 Jan;21(1):18-23. doi: 10.1681/ASN.2009030300. Epub 2009 Nov 16. Review.

12.

Drug discovery for overcoming chronic kidney disease (CKD): new therapy for CKD by a (pro)renin-receptor-blocking decoy peptide.

Ichihara A, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Itoh H.

J Pharmacol Sci. 2009 Jan;109(1):20-3. Review.

13.

Critical roles of (pro)renin receptor-bound prorenin in diabetes and hypertension: sallies into therapeutic approach.

Ichihara A, Itoh H, Inagami T.

J Am Soc Hypertens. 2008 Jan-Feb;2(1):15-9. doi: 10.1016/j.jash.2007.08.001.

PMID:
20409880
14.

Cultured neonatal rat cardiac myocytes and fibroblasts do not synthesize renin or angiotensinogen: evidence for stretch-induced cardiomyocyte hypertrophy independent of angiotensin II.

van Kesteren CA, Saris JJ, Dekkers DH, Lamers JM, Saxena PR, Schalekamp MA, Danser AH.

Cardiovasc Res. 1999 Jul;43(1):148-56.

PMID:
10536699
15.

Association of (pro)renin receptor mRNA expression with angiotensin-converting enzyme mRNA expression in human artery.

Takemitsu T, Ichihara A, Kaneshiro Y, Sakoda M, Kurauchi-Mito A, Narita T, Kinouchi K, Yamashita N, Itoh H.

Am J Nephrol. 2009;30(4):361-70. doi: 10.1159/000232199. Epub 2009 Jul 30.

PMID:
19641301
16.

Prorenin induces ERK activation in endothelial cells to enhance neovascularization independently of the renin-angiotensin system.

Uraoka M, Ikeda K, Nakagawa Y, Koide M, Akakabe Y, Nakano-Kurimoto R, Takahashi T, Matoba S, Yamada H, Okigaki M, Matsubara H.

Biochem Biophys Res Commun. 2009 Dec 25;390(4):1202-7. doi: 10.1016/j.bbrc.2009.10.121. Epub 2009 Oct 29.

PMID:
19879243
17.

Prorenin receptor blockade inhibits development of glomerulosclerosis in diabetic angiotensin II type 1a receptor-deficient mice.

Ichihara A, Suzuki F, Nakagawa T, Kaneshiro Y, Takemitsu T, Sakoda M, Nabi AH, Nishiyama A, Sugaya T, Hayashi M, Inagami T.

J Am Soc Nephrol. 2006 Jul;17(7):1950-61. Epub 2006 May 31.

18.

Prorenin and the (pro)renin receptor: do they have a pathogenic role in the retina?

Wilkinson-Berka JL, Miller AG, Fletcher EL.

Front Biosci (Elite Ed). 2010 Jun 1;2:1054-64. Review.

PMID:
20515775
19.

(Pro)renin promotes fibrosis gene expression in HEK cells through a Nox4-dependent mechanism.

Clavreul N, Sansilvestri-Morel P, Magard D, Verbeuren TJ, Rupin A.

Am J Physiol Renal Physiol. 2011 Jun;300(6):F1310-8. doi: 10.1152/ajprenal.00119.2010. Epub 2011 Mar 16.

20.

Prorenin induces intracellular signaling in cardiomyocytes independently of angiotensin II.

Saris JJ, 't Hoen PA, Garrelds IM, Dekkers DH, den Dunnen JT, Lamers JM, Jan Danser AH.

Hypertension. 2006 Oct;48(4):564-71. Epub 2006 Aug 28.

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