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Items: 1 to 20 of 259

1.

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells.

Naidu SR, Love IM, Imbalzano AN, Grossman SR, Androphy EJ.

Oncogene. 2009 Jul 9;28(27):2492-501. doi: 10.1038/onc.2009.121. Epub 2009 May 18.

2.

Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.

Keenen B, Qi H, Saladi SV, Yeung M, de la Serna IL.

Oncogene. 2010 Jan 7;29(1):81-92. doi: 10.1038/onc.2009.304. Epub 2009 Sep 28.

3.

SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation.

Banine F, Bartlett C, Gunawardena R, Muchardt C, Yaniv M, Knudsen ES, Weissman BE, Sherman LS.

Cancer Res. 2005 May 1;65(9):3542-7.

4.

The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.

Xu Y, Zhang J, Chen X.

J Biol Chem. 2007 Dec 28;282(52):37429-35. Epub 2007 Oct 15.

5.

Oncogenesis caused by loss of the SNF5 tumor suppressor is dependent on activity of BRG1, the ATPase of the SWI/SNF chromatin remodeling complex.

Wang X, Sansam CG, Thom CS, Metzger D, Evans JA, Nguyen PT, Roberts CW.

Cancer Res. 2009 Oct 15;69(20):8094-101. doi: 10.1158/0008-5472.CAN-09-0733. Epub 2009 Sep 29.

6.

SWI/SNF enzymes promote SOX10- mediated activation of myelin gene expression.

Marathe HG, Mehta G, Zhang X, Datar I, Mehrotra A, Yeung KC, de la Serna IL.

PLoS One. 2013 Jul 16;8(7):e69037. doi: 10.1371/journal.pone.0069037. Print 2013.

7.

The BRG1 ATPase of chromatin remodeling complexes is involved in modulation of mesenchymal stem cell senescence through RB-P53 pathways.

Alessio N, Squillaro T, Cipollaro M, Bagella L, Giordano A, Galderisi U.

Oncogene. 2010 Oct 7;29(40):5452-63. doi: 10.1038/onc.2010.285. Epub 2010 Aug 9.

PMID:
20697355
8.

Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.

Inayoshi Y, Miyake K, Machida Y, Kaneoka H, Terajima M, Dohda T, Takahashi M, Iijima S.

J Biochem. 2006 Feb;139(2):177-88.

PMID:
16452305
9.

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

Oike T, Ogiwara H, Tominaga Y, Ito K, Ando O, Tsuta K, Mizukami T, Shimada Y, Isomura H, Komachi M, Furuta K, Watanabe S, Nakano T, Yokota J, Kohno T.

Cancer Res. 2013 Sep 1;73(17):5508-18. doi: 10.1158/0008-5472.CAN-12-4593. Epub 2013 Jul 19.

10.
11.

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

Kothandapani A, Gopalakrishnan K, Kahali B, Reisman D, Patrick SM.

Exp Cell Res. 2012 Oct 1;318(16):1973-86. doi: 10.1016/j.yexcr.2012.06.011. Epub 2012 Jun 18.

12.

MITF-independent pro-survival role of BRG1-containing SWI/SNF complex in melanoma cells.

Ondrušová L, Vachtenheim J, Réda J, Záková P, Benková K.

PLoS One. 2013;8(1):e54110. doi: 10.1371/journal.pone.0054110. Epub 2013 Jan 17.

13.

Casein kinase 2-mediated phosphorylation of Brahma-related gene 1 controls myoblast proliferation and contributes to SWI/SNF complex composition.

Padilla-Benavides T, Nasipak BT, Paskavitz AL, Haokip DT, Schnabl JM, Nickerson JA, Imbalzano AN.

J Biol Chem. 2017 Nov 10;292(45):18592-18607. doi: 10.1074/jbc.M117.799676. Epub 2017 Sep 22.

14.

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

Endo M, Yasui K, Zen Y, Gen Y, Zen K, Tsuji K, Dohi O, Mitsuyoshi H, Tanaka S, Taniwaki M, Nakanuma Y, Arii S, Yoshikawa T.

Liver Int. 2013 Jan;33(1):105-17. doi: 10.1111/liv.12005. Epub 2012 Oct 22.

PMID:
23088494
15.

Transcriptional activation by pRB and its coordination with SWI/SNF recruitment.

Flowers S, Beck GR Jr, Moran E.

Cancer Res. 2010 Nov 1;70(21):8282-7. doi: 10.1158/0008-5472.CAN-10-2205. Epub 2010 Sep 17.

16.

Brg1 regulates the transcription of human papillomavirus type 18 E6 and E7 genes.

He H, Luo Y.

Cell Cycle. 2012 Feb 1;11(3):617-27. doi: 10.4161/cc.11.3.19115. Epub 2012 Feb 1.

PMID:
22262178
17.

De-regulated expression of the BRG1 chromatin remodeling factor in bone marrow mesenchymal stromal cells induces senescence associated with the silencing of NANOG and changes in the levels of chromatin proteins.

Squillaro T, Severino V, Alessio N, Farina A, Di Bernardo G, Cipollaro M, Peluso G, Chambery A, Galderisi U.

Cell Cycle. 2015;14(8):1315-26. doi: 10.4161/15384101.2014.995053.

18.

58-kDa microspherule protein (MSP58) is novel Brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway.

Hsu CC, Lee YC, Yeh SH, Chen CH, Wu CC, Wang TY, Chen YN, Hung LY, Liu YW, Chen HK, Hsiao YT, Wang WS, Tsou JH, Tsou YH, Wu MH, Chang WC, Lin DY.

J Biol Chem. 2012 Jun 29;287(27):22533-48. doi: 10.1074/jbc.M111.335331. Epub 2012 May 4.

19.

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

Sun A, Tawfik O, Gayed B, Thrasher JB, Hoestje S, Li C, Li B.

Prostate. 2007 Feb 1;67(2):203-13.

PMID:
17075831
20.

SWI/SNF chromatin remodeling complex is critical for the expression of microphthalmia-associated transcription factor in melanoma cells.

Vachtenheim J, Ondrusová L, Borovanský J.

Biochem Biophys Res Commun. 2010 Feb 12;392(3):454-9. doi: 10.1016/j.bbrc.2010.01.048. Epub 2010 Jan 18. Erratum in: Biochem Biophys Res Commun. 2010 May 14;395(4):585.

PMID:
20083088

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