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Items: 1 to 20 of 374

1.

Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.

Rathinakumar R, Walkenhorst WF, Wimley WC.

J Am Chem Soc. 2009 Jun 10;131(22):7609-17. doi: 10.1021/ja8093247.

2.

High-throughput discovery of broad-spectrum peptide antibiotics.

Rathinakumar R, Wimley WC.

FASEB J. 2010 Sep;24(9):3232-8. doi: 10.1096/fj.10-157040. Epub 2010 Apr 21.

3.

Antimicrobial properties of membrane-active dodecapeptides derived from MSI-78.

Monteiro C, Fernandes M, Pinheiro M, Maia S, Seabra CL, Ferreira-da-Silva F, Costa F, Reis S, Gomes P, Martins MC.

Biochim Biophys Acta. 2015 May;1848(5):1139-46. doi: 10.1016/j.bbamem.2015.02.001. Epub 2015 Feb 10.

5.

Effect of stereochemistry, chain length and sequence pattern on antimicrobial properties of short synthetic β-sheet forming peptide amphiphiles.

Ong ZY, Cheng J, Huang Y, Xu K, Ji Z, Fan W, Yang YY.

Biomaterials. 2014 Jan;35(4):1315-25. doi: 10.1016/j.biomaterials.2013.10.053. Epub 2013 Nov 7.

PMID:
24211081
6.

Preassembly of membrane-active peptides is an important factor in their selectivity toward target cells.

Sal-Man N, Oren Z, Shai Y.

Biochemistry. 2002 Oct 1;41(39):11921-30.

PMID:
12269837
8.

Potential of novel antimicrobial peptide P3 from bovine erythrocytes and its analogs to disrupt bacterial membranes in vitro and display activity against drug-resistant bacteria in a mouse model.

Zhang Q, Xu Y, Wang Q, Hang B, Sun Y, Wei X, Hu J.

Antimicrob Agents Chemother. 2015 May;59(5):2835-41. doi: 10.1128/AAC.04932-14. Epub 2015 Mar 9.

9.

Biomolecular engineering by combinatorial design and high-throughput screening: small, soluble peptides that permeabilize membranes.

Rathinakumar R, Wimley WC.

J Am Chem Soc. 2008 Jul 30;130(30):9849-58. doi: 10.1021/ja8017863. Epub 2008 Jul 9.

10.

Interaction of polyphemusin I and structural analogs with bacterial membranes, lipopolysaccharide, and lipid monolayers.

Zhang L, Scott MG, Yan H, Mayer LD, Hancock RE.

Biochemistry. 2000 Nov 28;39(47):14504-14.

PMID:
11087404
11.

Peptides from American alligator plasma are antimicrobial against multi-drug resistant bacterial pathogens including Acinetobacter baumannii.

Barksdale SM, Hrifko EJ, Chung EM, van Hoek ML.

BMC Microbiol. 2016 Aug 19;16(1):189. doi: 10.1186/s12866-016-0799-z.

12.

Design of antimicrobial peptide arenicin analogs with improved therapeutic indices.

Panteleev PV, Bolosov IA, Balandin SV, Ovchinnikova TV.

J Pept Sci. 2015 Feb;21(2):105-13. doi: 10.1002/psc.2732. Epub 2014 Dec 30.

PMID:
25557880
13.
14.

Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum.

Bagheri M, Beyermann M, Dathe M.

Antimicrob Agents Chemother. 2009 Mar;53(3):1132-41. doi: 10.1128/AAC.01254-08. Epub 2008 Dec 22.

15.

Design of potent, non-toxic antimicrobial agents based upon the naturally occurring frog skin peptides, ascaphin-8 and peptide XT-7.

Conlon JM, Galadari S, Raza H, Condamine E.

Chem Biol Drug Des. 2008 Jul;72(1):58-64. doi: 10.1111/j.1747-0285.2008.00671.x. Epub 2008 Jun 12.

PMID:
18554256
16.

A 17-mer Membrane-Active MSI-78 Derivative with Improved Selectivity toward Bacterial Cells.

Monteiro C, Pinheiro M, Fernandes M, Maia S, Seabra CL, Ferreira-da-Silva F, Reis S, Gomes P, Martins MC.

Mol Pharm. 2015 Aug 3;12(8):2904-11. doi: 10.1021/acs.molpharmaceut.5b00113. Epub 2015 Jul 1.

PMID:
26066462
17.

Antimicrobial potency and selectivity of simplified symmetric-end peptides.

Dong N, Zhu X, Chou S, Shan A, Li W, Jiang J.

Biomaterials. 2014 Sep;35(27):8028-39. doi: 10.1016/j.biomaterials.2014.06.005. Epub 2014 Jun 19.

PMID:
24952979
18.

Reverse engineering truncations of an antimicrobial peptide dimer to identify the origins of potency and broad spectrum of action.

Anantharaman A, Sahal D.

J Med Chem. 2010 Aug 26;53(16):6079-88. doi: 10.1021/jm100483y.

PMID:
20681539
19.

Lipid selectivity in novel antimicrobial peptides: Implication on antimicrobial and hemolytic activity.

Maturana P, Martinez M, Noguera ME, Santos NC, Disalvo EA, Semorile L, Maffia PC, Hollmann A.

Colloids Surf B Biointerfaces. 2017 May 1;153:152-159. doi: 10.1016/j.colsurfb.2017.02.003. Epub 2017 Feb 13.

PMID:
28236791
20.

Alpha-helical cationic antimicrobial peptides: relationships of structure and function.

Huang Y, Huang J, Chen Y.

Protein Cell. 2010 Feb;1(2):143-52. doi: 10.1007/s13238-010-0004-3. Epub 2010 Feb 6. Review.

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