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NKT cells mediate pulmonary inflammation and dysfunction in murine sickle cell disease through production of IFN-gamma and CXCR3 chemokines.

Wallace KL, Marshall MA, Ramos SI, Lannigan JA, Field JJ, Strieter RM, Linden J.

Blood. 2009 Jul 16;114(3):667-76. doi: 10.1182/blood-2009-02-205492. Epub 2009 May 11.


Adenosine A2A receptors induced on iNKT and NK cells reduce pulmonary inflammation and injury in mice with sickle cell disease.

Wallace KL, Linden J.

Blood. 2010 Dec 2;116(23):5010-20. doi: 10.1182/blood-2010-06-290643. Epub 2010 Aug 26.


Regulation of pulmonary fibrosis by chemokine receptor CXCR3.

Jiang D, Liang J, Hodge J, Lu B, Zhu Z, Yu S, Fan J, Gao Y, Yin Z, Homer R, Gerard C, Noble PW.

J Clin Invest. 2004 Jul;114(2):291-9.


Liver inflammation in a mouse model of Th1 hepatitis despite the absence of invariant NKT cells or the Th1 chemokine receptors CXCR3 and CCR5.

Cripps JG, Celaj S, Burdick M, Strieter RM, Gorham JD.

Lab Invest. 2012 Oct;92(10):1461-71. doi: 10.1038/labinvest.2012.104. Epub 2012 Aug 20.


Natural killer T (NKT) cells attenuate bleomycin-induced pulmonary fibrosis by producing interferon-gamma.

Kim JH, Kim HY, Kim S, Chung JH, Park WS, Chung DH.

Am J Pathol. 2005 Nov;167(5):1231-41.


Blockade of CXCR3 receptor:ligand interactions reduces leukocyte recruitment to the lung and the severity of experimental idiopathic pneumonia syndrome.

Hildebrandt GC, Corrion LA, Olkiewicz KM, Lu B, Lowler K, Duffner UA, Moore BB, Kuziel WA, Liu C, Cooke KR.

J Immunol. 2004 Aug 1;173(3):2050-9.


Chemokine monokine induced by IFN-gamma/CXC chemokine ligand 9 stimulates T lymphocyte proliferation and effector cytokine production.

Whiting D, Hsieh G, Yun JJ, Banerji A, Yao W, Fishbein MC, Belperio J, Strieter RM, Bonavida B, Ardehali A.

J Immunol. 2004 Jun 15;172(12):7417-24.


Th1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD Mice.

Kornete M, Mason ES, Girouard J, Lafferty EI, Qureshi S, Piccirillo CA.

PLoS One. 2015 May 6;10(5):e0126311. doi: 10.1371/journal.pone.0126311. eCollection 2015.


CXCL10+ T cells and NK cells assist in the recruitment and activation of CXCR3+ and CXCL11+ leukocytes during Mycobacteria-enhanced colitis.

Singh UP, Singh R, Singh S, Karls RK, Quinn FD, Taub DD, Lillard JW Jr.

BMC Immunol. 2008 Jun 4;9:25. doi: 10.1186/1471-2172-9-25.


Natural killer T cells regulate the homing of chemokine CXC receptor 3-positive regulatory T cells to the liver in mice.

Santodomingo-Garzon T, Han J, Le T, Yang Y, Swain MG.

Hepatology. 2009 Apr;49(4):1267-76. doi: 10.1002/hep.22761.


Recruitment of natural killer cells in advanced stages of endogenously arising B-cell lymphoma: implications for therapeutic cell transfer.

Przewoznik M, Hömberg N, Naujoks M, Pötzl J, Münchmeier N, Brenner CD, Anz D, Bourquin C, Nelson PJ, Röcken M, Mocikat R.

J Immunother. 2012 Apr;35(3):217-22. doi: 10.1097/CJI.0b013e318247440a.


CXCL10-producing mucosal CD4+ T cells, NK cells, and NKT cells are associated with chronic colitis in IL-10(-/-) mice, which can be abrogated by anti-CXCL10 antibody inhibition.

Singh UP, Singh S, Singh R, Cong Y, Taub DD, Lillard JW Jr.

J Interferon Cytokine Res. 2008 Jan;28(1):31-43. doi: 10.1089/jir.2007.0059.


Direct engagement of TLR4 in invariant NKT cells regulates immune diseases by differential IL-4 and IFN-γ production in mice.

Kim JH, Kim HS, Kim HY, Oh SJ, Chung DH.

PLoS One. 2012;7(9):e45348. doi: 10.1371/journal.pone.0045348. Epub 2012 Sep 19.


IFN-gamma-inducible chemokines enhance adaptive immunity and colitis.

Singh UP, Singh S, Iqbal N, Weaver CT, McGhee JR, Lillard JW Jr.

J Interferon Cytokine Res. 2003 Oct;23(10):591-600.


Activation of decidual invariant natural killer T cells promotes lipopolysaccharide-induced preterm birth.

Li L, Yang J, Jiang Y, Tu J, Schust DJ.

Mol Hum Reprod. 2015 Apr;21(4):369-81. doi: 10.1093/molehr/gav001. Epub 2015 Jan 14.


Heparin displaces interferon-gamma-inducible chemokines (IP-10, I-TAC, and Mig) sequestered in the vasculature and inhibits the transendothelial migration and arterial recruitment of T cells.

Ranjbaran H, Wang Y, Manes TD, Yakimov AO, Akhtar S, Kluger MS, Pober JS, Tellides G.

Circulation. 2006 Sep 19;114(12):1293-300. Epub 2006 Aug 28.


CXCR3 ligands contribute to Th1-induced inflammation but not to homing of Th1 cells into the lung.

Manicone AM, Burkhart KM, Lu B, Clark JG.

Exp Lung Res. 2008 Sep;34(7):391-407. doi: 10.1080/01902140802221987.


Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production.

Matsuda H, Takeda K, Koya T, Okamoto M, Shiraishi Y, Miyahara N, Dakhama A, Matsuda JL, Gapin L, Gelfand EW.

J Immunol. 2010 Jul 1;185(1):253-62. doi: 10.4049/jimmunol.0902301. Epub 2010 Jun 4.

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