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Items: 1 to 20 of 230

1.

Haematopoietic malignancies caused by dysregulation of a chromatin-binding PHD finger.

Wang GG, Song J, Wang Z, Dormann HL, Casadio F, Li H, Luo JL, Patel DJ, Allis CD.

Nature. 2009 Jun 11;459(7248):847-51. doi: 10.1038/nature08036.

2.

NUP98-PHF23 is a chromatin-modifying oncoprotein that causes a wide array of leukemias sensitive to inhibition of PHD histone reader function.

Gough SM, Lee F, Yang F, Walker RL, Zhu YJ, Pineda M, Onozawa M, Chung YJ, Bilke S, Wagner EK, Denu JM, Ning Y, Xu B, Wang GG, Meltzer PS, Aplan PD.

Cancer Discov. 2014 May;4(5):564-77. doi: 10.1158/2159-8290.CD-13-0419. Epub 2014 Feb 17.

3.

NUP98-NSD1 links H3K36 methylation to Hox-A gene activation and leukaemogenesis.

Wang GG, Cai L, Pasillas MP, Kamps MP.

Nat Cell Biol. 2007 Jul;9(7):804-12. Epub 2007 Jun 24.

PMID:
17589499
4.

Molecular mechanism of histone H3K4me3 recognition by plant homeodomain of ING2.

Peña PV, Davrazou F, Shi X, Walter KL, Verkhusha VV, Gozani O, Zhao R, Kutateladze TG.

Nature. 2006 Jul 6;442(7098):100-3. Epub 2006 May 21.

5.

Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF.

Li H, Ilin S, Wang W, Duncan EM, Wysocka J, Allis CD, Patel DJ.

Nature. 2006 Jul 6;442(7098):91-5. Epub 2006 May 21.

6.

A PHD finger of NURF couples histone H3 lysine 4 trimethylation with chromatin remodelling.

Wysocka J, Swigut T, Xiao H, Milne TA, Kwon SY, Landry J, Kauer M, Tackett AJ, Chait BT, Badenhorst P, Wu C, Allis CD.

Nature. 2006 Jul 6;442(7098):86-90. Epub 2006 May 21.

PMID:
16728976
7.

Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor.

Peña PV, Hom RA, Hung T, Lin H, Kuo AJ, Wong RP, Subach OM, Champagne KS, Zhao R, Verkhusha VV, Li G, Gozani O, Kutateladze TG.

J Mol Biol. 2008 Jul 4;380(2):303-12. doi: 10.1016/j.jmb.2008.04.061. Epub 2008 May 2.

8.

ING2 PHD domain links histone H3 lysine 4 methylation to active gene repression.

Shi X, Hong T, Walter KL, Ewalt M, Michishita E, Hung T, Carney D, Peña P, Lan F, Kaadige MR, Lacoste N, Cayrou C, Davrazou F, Saha A, Cairns BR, Ayer DE, Kutateladze TG, Shi Y, Côté J, Chua KF, Gozani O.

Nature. 2006 Jul 6;442(7098):96-9. Epub 2006 May 21.

9.

Structural insight into histone recognition by the ING PHD fingers.

Champagne KS, Kutateladze TG.

Curr Drug Targets. 2009 May;10(5):432-41. Review.

10.

Mechanism of Histone H3K4me3 Recognition by the Plant Homeodomain of Inhibitor of Growth 3.

Kim S, Natesan S, Cornilescu G, Carlson S, Tonelli M, McClurg UL, Binda O, Robson CN, Markley JL, Balaz S, Glass KC.

J Biol Chem. 2016 Aug 26;291(35):18326-41. doi: 10.1074/jbc.M115.690651. Epub 2016 Jun 8.

11.

NUP98 gene fusions and hematopoietic malignancies: common themes and new biologic insights.

Gough SM, Slape CI, Aplan PD.

Blood. 2011 Dec 8;118(24):6247-57. doi: 10.1182/blood-2011-07-328880. Epub 2011 Sep 26. Review.

12.

Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription.

Chang PY, Hom RA, Musselman CA, Zhu L, Kuo A, Gozani O, Kutateladze TG, Cleary ML.

J Mol Biol. 2010 Jul 9;400(2):137-44. doi: 10.1016/j.jmb.2010.05.005. Epub 2010 May 7.

13.

RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V(D)J recombination.

Matthews AG, Kuo AJ, Ramón-Maiques S, Han S, Champagne KS, Ivanov D, Gallardo M, Carney D, Cheung P, Ciccone DN, Walter KL, Utz PJ, Shi Y, Kutateladze TG, Yang W, Gozani O, Oettinger MA.

Nature. 2007 Dec 13;450(7172):1106-10. Epub 2007 Nov 21.

14.

Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression.

Lan F, Collins RE, De Cegli R, Alpatov R, Horton JR, Shi X, Gozani O, Cheng X, Shi Y.

Nature. 2007 Aug 9;448(7154):718-22.

15.

RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

Christensen J, Agger K, Cloos PA, Pasini D, Rose S, Sennels L, Rappsilber J, Hansen KH, Salcini AE, Helin K.

Cell. 2007 Mar 23;128(6):1063-76. Epub 2007 Feb 22.

16.

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

Iwase S, Lan F, Bayliss P, de la Torre-Ubieta L, Huarte M, Qi HH, Whetstine JR, Bonni A, Roberts TM, Shi Y.

Cell. 2007 Mar 23;128(6):1077-88. Epub 2007 Feb 22.

17.

Epigenetic dysregulation of leukaemic HOX code in MLL-rearranged leukaemia mouse model.

Ng RK, Kong CT, So CC, Lui WC, Chan YF, Leung KC, So KC, Tsang HM, Chan LC, Sham MH.

J Pathol. 2014 Jan;232(1):65-74. doi: 10.1002/path.4279.

PMID:
24122813
18.

ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation.

Hung T, Binda O, Champagne KS, Kuo AJ, Johnson K, Chang HY, Simon MD, Kutateladze TG, Gozani O.

Mol Cell. 2009 Jan 30;33(2):248-56. doi: 10.1016/j.molcel.2008.12.016.

19.

The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2.

Ramón-Maiques S, Kuo AJ, Carney D, Matthews AG, Oettinger MA, Gozani O, Yang W.

Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):18993-8. Epub 2007 Nov 19.

20.

PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks.

Baker LA, Allis CD, Wang GG.

Mutat Res. 2008 Dec 1;647(1-2):3-12. doi: 10.1016/j.mrfmmm.2008.07.004. Epub 2008 Jul 17. Review.

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