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Items: 1 to 20 of 92

1.

NF-kappaB and phosphatidylinositol 3-kinase activity mediates the HCMV-induced atypical M1/M2 polarization of monocytes.

Chan G, Bivins-Smith ER, Smith MS, Yurochko AD.

Virus Res. 2009 Sep;144(1-2):329-33. doi: 10.1016/j.virusres.2009.04.026. Epub 2009 May 7.

2.

Roles of phosphatidylinositol 3-kinase and NF-kappaB in human cytomegalovirus-mediated monocyte diapedesis and adhesion: strategy for viral persistence.

Smith MS, Bivins-Smith ER, Tilley AM, Bentz GL, Chan G, Minard J, Yurochko AD.

J Virol. 2007 Jul;81(14):7683-94. Epub 2007 May 16.

3.

Transcriptome analysis of NF-kappaB- and phosphatidylinositol 3-kinase-regulated genes in human cytomegalovirus-infected monocytes.

Chan G, Bivins-Smith ER, Smith MS, Yurochko AD.

J Virol. 2008 Jan;82(2):1040-6. Epub 2007 Nov 14.

4.

Human cytomegalovirus-regulated paxillin in monocytes links cellular pathogenic motility to the process of viral entry.

Nogalski MT, Chan G, Stevenson EV, Gray S, Yurochko AD.

J Virol. 2011 Feb;85(3):1360-9. doi: 10.1128/JVI.02090-10. Epub 2010 Nov 17.

5.

Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage.

Chan G, Bivins-Smith ER, Smith MS, Smith PM, Yurochko AD.

J Immunol. 2008 Jul 1;181(1):698-711.

6.
7.

HCMV activates PI(3)K in monocytes and promotes monocyte motility and transendothelial migration in a PI(3)K-dependent manner.

Smith MS, Bentz GL, Smith PM, Bivins ER, Yurochko AD.

J Leukoc Biol. 2004 Jul;76(1):65-76. Epub 2004 Apr 23.

PMID:
15107461
8.

HCMV utilizes a non-traditional STAT1 activation cascade via signaling through EGFR and integrins to efficiently promote the motility, differentiation, and polarization of infected monocytes.

Collins-McMillen D, Stevenson EV, Kim JH, Lee BJ, Cieply SJ, Nogalski MT, Chan GC, Frost RW 3rd, Spohn CR, Yurochko AD.

J Virol. 2017 Oct 11. pii: JVI.00622-17. doi: 10.1128/JVI.00622-17. [Epub ahead of print]

PMID:
29021395
9.

Human cytomegalovirus stimulates monocyte-to-macrophage differentiation via the temporal regulation of caspase 3.

Chan G, Nogalski MT, Yurochko AD.

J Virol. 2012 Oct;86(19):10714-23. doi: 10.1128/JVI.07129-11. Epub 2012 Jul 25.

10.

Human Cytomegalovirus Induces an Atypical Activation of Akt To Stimulate the Survival of Short-Lived Monocytes.

Cojohari O, Peppenelli MA, Chan GC.

J Virol. 2016 Jun 24;90(14):6443-52. doi: 10.1128/JVI.00214-16. Print 2016 Jul 15.

11.

Human cytomegalovirus induction of a unique signalsome during viral entry into monocytes mediates distinct functional changes: a strategy for viral dissemination.

Chan G, Nogalski MT, Stevenson EV, Yurochko AD.

J Leukoc Biol. 2012 Oct;92(4):743-52. doi: 10.1189/jlb.0112040. Epub 2012 Jun 19. Review.

12.

Human Cytomegalovirus Stimulates the Synthesis of Select Akt-Dependent Antiapoptotic Proteins during Viral Entry To Promote Survival of Infected Monocytes.

Peppenelli MA, Arend KC, Cojohari O, Moorman NJ, Chan GC.

J Virol. 2016 Jan 6;90(6):3138-47. doi: 10.1128/JVI.02879-15.

13.

The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha.

Nogalski MT, Podduturi JP, DeMeritt IB, Milford LE, Yurochko AD.

J Virol. 2007 May;81(10):5305-14. Epub 2007 Mar 7.

14.

Targeting the NF-kappaB pathway through pharmacological inhibition of IKK2 prevents human cytomegalovirus replication and virus-induced inflammatory response in infected endothelial cells.

Caposio P, Musso T, Luganini A, Inoue H, Gariglio M, Landolfo S, Gribaudo G.

Antiviral Res. 2007 Mar;73(3):175-84. Epub 2006 Oct 23.

PMID:
17070604
15.

PI3K-dependent upregulation of Mcl-1 by human cytomegalovirus is mediated by epidermal growth factor receptor and inhibits apoptosis in short-lived monocytes.

Chan G, Nogalski MT, Bentz GL, Smith MS, Parmater A, Yurochko AD.

J Immunol. 2010 Mar 15;184(6):3213-22. doi: 10.4049/jimmunol.0903025. Epub 2010 Feb 19.

16.

Vibrio cholerae porin OmpU mediates M1-polarization of macrophages/monocytes via TLR1/TLR2 activation.

Khan J, Sharma PK, Mukhopadhaya A.

Immunobiology. 2015 Nov;220(11):1199-209. doi: 10.1016/j.imbio.2015.06.009. Epub 2015 Jun 5.

PMID:
26093918
17.

HCMV IL-10 suppresses cytokine expression in monocytes through inhibition of nuclear factor-kappaB.

Nachtwey J, Spencer JV.

Viral Immunol. 2008 Dec;21(4):477-82. doi: 10.1089/vim.2008.0048.

18.
19.

HCMV reprogramming of infected monocyte survival and differentiation: a Goldilocks phenomenon.

Stevenson EV, Collins-McMillen D, Kim JH, Cieply SJ, Bentz GL, Yurochko AD.

Viruses. 2014 Feb 13;6(2):782-807. doi: 10.3390/v6020782. Review.

20.

Cytomegalovirus enhances macrophage TLR expression and MyD88-mediated signal transduction to potentiate inducible inflammatory responses.

Smith PD, Shimamura M, Musgrove LC, Dennis EA, Bimczok D, Novak L, Ballestas M, Fenton A, Dandekar S, Britt WJ, Smythies LE.

J Immunol. 2014 Dec 1;193(11):5604-12. doi: 10.4049/jimmunol.1302608. Epub 2014 Oct 29.

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