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Items: 1 to 20 of 98

1.

Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.

Le LQ, Shipman T, Burns DK, Parada LF.

Cell Stem Cell. 2009 May 8;4(5):453-63. doi: 10.1016/j.stem.2009.03.017.

2.

The neurofibroma cell of origin: SKPs expand the playing field.

Morris ZS, McClatchey AI.

Cell Stem Cell. 2009 May 8;4(5):371-2. doi: 10.1016/j.stem.2009.04.010.

3.

Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma.

Chen Z, Liu C, Patel AJ, Liao CP, Wang Y, Le LQ.

Cancer Cell. 2014 Nov 10;26(5):695-706. doi: 10.1016/j.ccell.2014.09.009. Epub 2014 Oct 30.

4.

Nf1-dependent tumors require a microenvironment containing Nf1+/-- and c-kit-dependent bone marrow.

Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y, Zhang S, Yang Y, Vakili ST, Yu M, Burns D, Robertson K, Hutchins G, Parada LF, Clapp DW.

Cell. 2008 Oct 31;135(3):437-48. doi: 10.1016/j.cell.2008.08.041.

5.

Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy.

Nebesio TD, Ming W, Chen S, Clegg T, Yuan J, Yang Y, Estwick SA, Li Y, Li X, Hingtgen CM, Yang FC.

Glia. 2007 Apr 1;55(5):527-36.

PMID:
17236191
6.

Tumor microenvironment and neurofibromatosis type I: connecting the GAPs.

Le LQ, Parada LF.

Oncogene. 2007 Jul 12;26(32):4609-16. Epub 2007 Feb 12. Review.

7.

Decreased expression of neurofibromin contributes to epithelial-mesenchymal transition in neurofibromatosis type 1.

Arima Y, Hayashi H, Kamata K, Goto TM, Sasaki M, Kuramochi A, Saya H.

Exp Dermatol. 2010 Aug;19(8):e136-41. doi: 10.1111/j.1600-0625.2009.01017.x.

8.

Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells.

Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N.

Cancer Cell. 2008 Feb;13(2):105-16. doi: 10.1016/j.ccr.2007.12.027.

9.

Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells.

Yang FC, Ingram DA, Chen S, Hingtgen CM, Ratner N, Monk KR, Clegg T, White H, Mead L, Wenning MJ, Williams DA, Kapur R, Atkinson SJ, Clapp DW.

J Clin Invest. 2003 Dec;112(12):1851-61.

10.

The activation of the WNT signaling pathway is a Hallmark in neurofibromatosis type 1 tumorigenesis.

Luscan A, Shackleford G, Masliah-Planchon J, Laurendeau I, Ortonne N, Varin J, Lallemand F, Leroy K, Dumaine V, Hivelin M, Borderie D, De Raedt T, Valeyrie-Allanore L, Larousserie F, Terris B, Lantieri L, Vidaud M, Vidaud D, Wolkenstein P, Parfait B, Bièche I, Massaad C, Pasmant E.

Clin Cancer Res. 2014 Jan 15;20(2):358-71. doi: 10.1158/1078-0432.CCR-13-0780. Epub 2013 Nov 11.

11.

Neurofibroma-associated growth factors activate a distinct signaling network to alter the function of neurofibromin-deficient endothelial cells.

Munchhof AM, Li F, White HA, Mead LE, Krier TR, Fenoglio A, Li X, Yuan J, Yang FC, Ingram DA.

Hum Mol Genet. 2006 Jun 1;15(11):1858-69. Epub 2006 Apr 28.

PMID:
16648142
12.

S100B and neurofibromin immunostaining and X-inactivation patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas.

Tucker T, Riccardi VM, Brown C, Fee J, Sutcliffe M, Vielkind J, Wechsler J, Wolkenstein P, Friedman JM.

J Neurosci Res. 2011 Sep;89(9):1451-60. doi: 10.1002/jnr.22654. Epub 2011 Jun 14.

PMID:
21674567
13.

The role of nerve microenvironment for neurofibroma development.

Liao CP, Pradhan S, Chen Z, Patel AJ, Booker RC, Le LQ.

Oncotarget. 2016 Sep 20;7(38):61500-61508. doi: 10.18632/oncotarget.11133.

14.

Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential.

Williams JP, Wu J, Johansson G, Rizvi TA, Miller SC, Geiger H, Malik P, Li W, Mukouyama YS, Cancelas JA, Ratner N.

Cell Stem Cell. 2008 Dec 4;3(6):658-69. doi: 10.1016/j.stem.2008.10.003.

15.

Influence of hormones and hormone metabolites on the growth of Schwann cells derived from embryonic stem cells and on tumor cell lines expressing variable levels of neurofibromin.

Roth TM, Ramamurthy P, Muir D, Wallace MR, Zhu Y, Chang L, Barald KF.

Dev Dyn. 2008 Feb;237(2):513-24. doi: 10.1002/dvdy.21430.

16.

The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.

Mashour GA, Ratner N, Khan GA, Wang HL, Martuza RL, Kurtz A.

Oncogene. 2001 Jan 4;20(1):97-105.

17.

Molecular, genetic, and cellular pathogenesis of neurofibromas and surgical implications.

Gottfried ON, Viskochil DH, Fults DW, Couldwell WT.

Neurosurgery. 2006 Jan;58(1):1-16; discussion 1-16. Review.

PMID:
16385324
18.

Does Schwann cell dedifferentiation originate dermal neurofibromas?

Iribar H, Jaka A, Ormaechea N, Tuneu A, Izeta A, Gutiérrez-Rivera A.

Exp Dermatol. 2016 Nov;25(11):901-903. doi: 10.1111/exd.13110.

PMID:
27303947
19.

It takes two to tango: mast cell and Schwann cell interactions in neurofibromas.

Viskochil DH.

J Clin Invest. 2003 Dec;112(12):1791-3. Review.

20.

The development of cutaneous neurofibromas.

Jouhilahti EM, Peltonen S, Callens T, Jokinen E, Heape AM, Messiaen L, Peltonen J.

Am J Pathol. 2011 Feb;178(2):500-5. doi: 10.1016/j.ajpath.2010.10.041.

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