Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 100

1.

Evaluation of 5-hydroxy-2,3-diaryl (substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anti angiogenic and anticancer agents.

Sanna VK, Jaggi M, Kumar V, Burman AC.

Invest New Drugs. 2010 Aug;28(4):363-80. doi: 10.1007/s10637-009-9256-2. Epub 2009 May 8.

PMID:
19424664
2.

Synthesis and evaluation of 4/5-hydroxy-2,3-diaryl(substituted)-cyclopent-2-en-1-ones as cis-restricted analogues of combretastatin A-4 as novel anticancer agents.

Gurjar MK, Wakharkar RD, Singh AT, Jaggi M, Borate HB, Shinde PD, Verma R, Rajendran P, Dutt S, Singh G, Sanna VK, Singh MK, Srivastava SK, Mahajan VA, Jadhav VH, Dutta K, Krishnan K, Chaudhary A, Agarwal SK, Mukherjee R, Burman AC.

J Med Chem. 2007 Apr 19;50(8):1744-53. Epub 2007 Mar 21.

PMID:
17373779
3.

New oxazole-bridged combretastatin A-4 analogues as potential vascular-disrupting agents.

Mahal K, Biersack B, Schobert R.

Int J Clin Pharmacol Ther. 2013 Jan;51(1):41-3. No abstract available.

4.

Structure-activity-relationship studies of conformationally restricted analogs of combretastatin A-4 derived from SU5416.

Pandit B, Sun Y, Chen P, Sackett DL, Hu Z, Rich W, Li C, Lewis A, Schaefer K, Li PK.

Bioorg Med Chem. 2006 Oct 1;14(19):6492-501. Epub 2006 Jul 24.

PMID:
16860559
5.

Sydnone Cycloaddition Route to Pyrazole-Based Analogs of Combretastatin A4.

Brown AW, Fisher M, Tozer GM, Kanthou C, Harrity JP.

J Med Chem. 2016 Oct 27;59(20):9473-9488. Epub 2016 Oct 7.

PMID:
27690431
6.

Identification of novel 1-indolyl acetate-5-nitroimidazole derivatives of combretastatin A-4 as potential tubulin polymerization inhibitors.

Yao YF, Wang ZC, Wu SY, Li QF, Yu C, Liang XY, Lv PC, Duan YT, Zhu HL.

Biochem Pharmacol. 2017 Aug 1;137:10-28. doi: 10.1016/j.bcp.2017.04.026. Epub 2017 Apr 27.

PMID:
28456516
7.

Synthesis and biological evaluation of novel 4,5-disubstituted 2H-1,2,3-triazoles as cis-constrained analogues of combretastatin A-4.

Madadi NR, Penthala NR, Howk K, Ketkar A, Eoff RL, Borrelli MJ, Crooks PA.

Eur J Med Chem. 2015 Oct 20;103:123-32. doi: 10.1016/j.ejmech.2015.08.041. Epub 2015 Aug 29.

8.

Inhibitory effect of riccardin D on growth of human non-small cell lung cancer: in vitro and in vivo studies.

Xue X, Sun DF, Sun CC, Liu HP, Yue B, Zhao CR, Lou HX, Qu XJ.

Lung Cancer. 2012 Jun;76(3):300-8. doi: 10.1016/j.lungcan.2011.12.013. Epub 2012 Jan 17.

PMID:
22261315
9.

Synthesis and biological evaluation of novel 3,4-diaryl-1,2,5-selenadiazol analogues of combretastatin A-4.

Guan Q, Yang F, Guo D, Xu J, Jiang M, Liu C, Bao K, Wu Y, Zhang W.

Eur J Med Chem. 2014 Nov 24;87:1-9. doi: 10.1016/j.ejmech.2014.09.046. Epub 2014 Sep 16.

PMID:
25233100
10.

Anti-tumor activity and mechanisms of a novel vascular disrupting agent, (Z)-3,4',5-trimethoxylstilbene-3'-O-phosphate disodium (M410).

Cai YC, Zou Y, Ye YL, Sun HY, Su QG, Wang ZX, Zeng ZL, Xian LJ.

Invest New Drugs. 2011 Apr;29(2):300-11. doi: 10.1007/s10637-009-9366-x. Epub 2009 Dec 11.

PMID:
20012336
11.

Discovery and optimization of a series of 2-aryl-4-amino-5-(3',4',5'-trimethoxybenzoyl)thiazoles as novel anticancer agents.

Romagnoli R, Baraldi PG, Salvador MK, Preti D, Aghazadeh Tabrizi M, Brancale A, Fu XH, Li J, Zhang SZ, Hamel E, Bortolozzi R, Porc├╣ E, Basso G, Viola G.

J Med Chem. 2012 Jun 14;55(11):5433-45. doi: 10.1021/jm300388h. Epub 2012 May 21.

12.

Synthesis and Biological Evaluations of 1,2-Diaryl Pyrroles as Analogues of Combretastatin A-4.

Sun J, Chen L, Liu C, Wang Z, Zuo D, Pan J, Qi H, Bao K, Wu Y, Zhang W.

Chem Biol Drug Des. 2015 Dec;86(6):1541-7. doi: 10.1111/cbdd.12617. Epub 2015 Sep 25.

PMID:
26202587
13.

Potent inhibition of Lewis lung cancer growth by heyneanol A from the roots of Vitis amurensis through apoptotic and anti-angiogenic activities.

Lee EO, Lee HJ, Hwang HS, Ahn KS, Chae C, Kang KS, Lu J, Kim SH.

Carcinogenesis. 2006 Oct;27(10):2059-69. Epub 2006 May 4.

PMID:
16675471
14.

Novel combretastatin A-4 derivative XN0502 induces cell cycle arrest and apoptosis in A549 cells.

Zhu H, Zhang J, Xue N, Hu Y, Yang B, He Q.

Invest New Drugs. 2010 Aug;28(4):493-501. doi: 10.1007/s10637-010-9424-4. Epub 2010 Mar 30.

PMID:
20352291
15.

Rapid synthesis of 4-arylchromenes from ortho-substituted alkynols: A versatile access to restricted isocombretastatin A-4 analogues as antitumor agents.

Renko D, Provot O, Rasolofonjatovo E, Bignon J, Rodrigo J, Dubois J, Brion JD, Hamze A, Alami M.

Eur J Med Chem. 2015 Jan 27;90:834-44. doi: 10.1016/j.ejmech.2014.12.024. Epub 2014 Dec 15.

PMID:
25528337
16.

Novel cis-restricted ╬▓-lactam combretastatin A-4 analogues display anti-vascular and anti-metastatic properties in vitro.

Nathwani SM, Hughes L, Greene LM, Carr M, O'Boyle NM, McDonnell S, Meegan MJ, Zisterer DM.

Oncol Rep. 2013 Feb;29(2):585-94. doi: 10.3892/or.2012.2181. Epub 2012 Dec 10.

PMID:
23232969
17.

Design, synthesis and anticancer properties of 5-arylbenzoxepins as conformationally restricted isocombretastatin A-4 analogs.

Rasolofonjatovo E, Provot O, Hamze A, Rodrigo J, Bignon J, Wdzieczak-Bakala J, Lenoir C, Desravines D, Dubois J, Brion JD, Alami M.

Eur J Med Chem. 2013 Apr;62:28-39. doi: 10.1016/j.ejmech.2012.12.042. Epub 2013 Jan 4.

PMID:
23353744
18.

SKLB1002, a novel potent inhibitor of VEGF receptor 2 signaling, inhibits angiogenesis and tumor growth in vivo.

Zhang S, Cao Z, Tian H, Shen G, Ma Y, Xie H, Liu Y, Zhao C, Deng S, Yang Y, Zheng R, Li W, Zhang N, Liu S, Wang W, Dai L, Shi S, Cheng L, Pan Y, Feng S, Zhao X, Deng H, Yang S, Wei Y.

Clin Cancer Res. 2011 Jul 1;17(13):4439-50. doi: 10.1158/1078-0432.CCR-10-3109. Epub 2011 May 27.

19.

Anti-angiogenic and anti-metastatic activity of synthetic phosphoethanolamine.

Ferreira AK, Freitas VM, Levy D, Ruiz JL, Bydlowski SP, Rici RE, Filho OM, Chierice GO, Maria DA.

PLoS One. 2013;8(3):e57937. doi: 10.1371/journal.pone.0057937. Epub 2013 Mar 14.

20.

Discovery and hit to lead optimization of novel combretastatin A-4 analogues: dependence of C-linker length and hybridization.

Provot O, Hamze A, Peyrat JF, Brion JD, Alami M.

Anticancer Agents Med Chem. 2013 Dec;13(10):1614-35.

PMID:
24261611

Supplemental Content

Support Center