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Items: 1 to 20 of 100

1.

Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation.

Villeneuve L, Wang RL, Bencic DC, Biales AD, Martinović D, Lazorchak JM, Toth G, Ankley GT.

Environ Toxicol Chem. 2009 Aug;28(8):1767-82. doi: 10.1897/08-653.1.

PMID:
19422270
2.

Linking the response of endocrine regulated genes to adverse effects on sex differentiation improves comprehension of aromatase inhibition in a Fish Sexual Development Test.

Muth-Köhne E, Westphal-Settele K, Brückner J, Konradi S, Schiller V, Schäfers C, Teigeler M, Fenske M.

Aquat Toxicol. 2016 Jul;176:116-27. doi: 10.1016/j.aquatox.2016.04.018. Epub 2016 Apr 20.

3.

Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17beta-trenbolone.

Zhang X, Hecker M, Park JW, Tompsett AR, Jones PD, Newsted J, Au DW, Kong R, Wu RS, Giesy JP.

Environ Toxicol Chem. 2008 Dec;27(12):2504-11. doi: 10.1897/08-082.1.

PMID:
18693774
4.

DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species.

Wang RL, Biales A, Bencic D, Lattier D, Kostich M, Villeneuve D, Ankley GT, Lazorchak J, Toth G.

Environ Toxicol Chem. 2008 Mar;27(3):652-63.

PMID:
17990945
5.

Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio).

Fenske M, Segner H.

Aquat Toxicol. 2004 Apr 14;67(2):105-26.

PMID:
15003697
6.

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: I. Data generation in a small fish model.

Villeneuve DL, Breen M, Bencic DC, Cavallin JE, Jensen KM, Makynen EA, Thomas LM, Wehmas LC, Conolly RB, Ankley GT.

Toxicol Sci. 2013 Jun;133(2):225-33. doi: 10.1093/toxsci/kft068. Epub 2013 Mar 14.

PMID:
23492810
7.

Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas).

Villeneuve DL, Knoebl I, Kahl MD, Jensen KM, Hammermeister DE, Greene KJ, Blake LS, Ankley GT.

Aquat Toxicol. 2006 Mar 10;76(3-4):353-68. Epub 2005 Dec 2.

PMID:
16330110
8.

Computational model of the fathead minnow hypothalamic-pituitary-gonadal axis: Incorporating protein synthesis in improving predictability of responses to endocrine active chemicals.

Breen M, Villeneuve DL, Ankley GT, Bencic D, Breen MS, Watanabe KH, Lloyd AL, Conolly RB.

Comp Biochem Physiol C Toxicol Pharmacol. 2016 May-Jun;183-184:36-45. doi: 10.1016/j.cbpc.2016.02.002. Epub 2016 Feb 12.

PMID:
26875912
9.

Profiling neuroendocrine gene expression changes following fadrozole-induced estrogen decline in the female goldfish.

Zhang D, Popesku JT, Martyniuk CJ, Xiong H, Duarte-Guterman P, Yao L, Xia X, Trudeau VL.

Physiol Genomics. 2009 Aug 7;38(3):351-61. doi: 10.1152/physiolgenomics.00051.2009. Epub 2009 Jun 9.

10.

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: II. Computational modeling.

Breen M, Villeneuve DL, Ankley GT, Bencic DC, Breen MS, Watanabe KH, Lloyd AL, Conolly RB.

Toxicol Sci. 2013 Jun;133(2):234-47. doi: 10.1093/toxsci/kft067. Epub 2013 Mar 9.

PMID:
23475784
11.

Benzo(a)pyrene decreases brain and ovarian aromatase mRNA expression in Fundulus heteroclitus.

Dong W, Wang L, Thornton C, Scheffler BE, Willett KL.

Aquat Toxicol. 2008 Jul 30;88(4):289-300. doi: 10.1016/j.aquatox.2008.05.006. Epub 2008 May 15.

12.

A transcriptomics-based biological framework for studying mechanisms of endocrine disruption in small fish species.

Wang RL, Bencic D, Villeneuve DL, Ankley GT, Lazorchak J, Edwards S.

Aquat Toxicol. 2010 Jul 1;98(3):230-44. doi: 10.1016/j.aquatox.2010.02.021. Epub 2010 Mar 11. Erratum in: Aquat Toxicol. 2011 Apr;102(3-4):232-5.

PMID:
20359757
13.

DNA microarray-based ecotoxicological biomarker discovery in a small fish model species.

Wang RL, Bencic D, Biales A, Lattier D, Kostich M, Villeneuve D, Ankley GT, Lazorchak J, Toth G.

Environ Toxicol Chem. 2008 Mar;27(3):664-75.

PMID:
17990946
14.

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor.

Villeneuve DL, Mueller ND, Martinović D, Makynen EA, Kahl MD, Jensen KM, Durhan EJ, Cavallin JE, Bencic D, Ankley GT.

Environ Health Perspect. 2009 Apr;117(4):624-31. doi: 10.1289/ehp.11891. Epub 2008 Dec 12.

15.

A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis.

Villeneuve DL, Larkin P, Knoebl I, Miracle AL, Kahl MD, Jensen KM, Makynen EA, Durhan EJ, Carter BJ, Denslow ND, Ankley GT.

Environ Sci Technol. 2007 Jan 1;41(1):321-30.

PMID:
17265966
16.

Effects of lifetime chemical inhibition of aromatase on the sexual differentiation, sperm characteristics and fertility of medaka (Oryzias latipes) and zebrafish (Danio rerio).

Thresher R, Gurney R, Canning M.

Aquat Toxicol. 2011 Oct;105(3-4):355-60. doi: 10.1016/j.aquatox.2011.07.008. Epub 2011 Jul 18.

PMID:
21819815
17.

Disruption of apoptosis pathways involved in zebrafish gonad differentiation by 17α-ethinylestradiol and fadrozole exposures.

Luzio A, Matos M, Santos D, Fontaínhas-Fernandes AA, Monteiro SM, Coimbra AM.

Aquat Toxicol. 2016 Aug;177:269-84. doi: 10.1016/j.aquatox.2016.05.029. Epub 2016 Jun 3.

PMID:
27337697
18.

Promoter characteristics of two cyp19 genes differentially expressed in the brain and ovary of teleost fish.

Tchoudakova A, Kishida M, Wood E, Callard GV.

J Steroid Biochem Mol Biol. 2001 Nov;78(5):427-39.

PMID:
11738553
19.

Rapid effects of the aromatase inhibitor fadrozole on steroid production and gene expression in the ovary of female fathead minnows (Pimephales promelas).

Schroeder AL, Ankley GT, Habib T, Garcia-Reyero N, Escalon BL, Jensen KM, Kahl MD, Durhan EJ, Makynen EA, Cavallin JE, Martinovic-Weigelt D, Perkins EJ, Villeneuve DL.

Gen Comp Endocrinol. 2017 Jul 21;252:79-87. doi: 10.1016/j.ygcen.2017.07.022. [Epub ahead of print]

PMID:
28736226
20.

Transcriptional regulatory dynamics of the hypothalamic-pituitary-gonadal axis and its peripheral pathways as impacted by the 3-beta HSD inhibitor trilostane in zebrafish (Danio rerio).

Wang RL, Bencic D, Lazorchak J, Villeneuve D, Ankley GT.

Ecotoxicol Environ Saf. 2011 Sep;74(6):1461-70. doi: 10.1016/j.ecoenv.2011.05.001. Epub 2011 May 12.

PMID:
21570121

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