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Expression of transgenic PPP1CC2 in the testis of Ppp1cc-null mice rescues spermatid viability and spermiation but does not restore normal sperm tail ultrastructure, sperm motility, or fertility.

Soler DC, Kadunganattil S, Ramdas S, Myers K, Roca J, Slaughter T, Pilder SH, Vijayaraghavan S.

Biol Reprod. 2009 Aug;81(2):343-52. doi: 10.1095/biolreprod.109.076398. Epub 2009 May 6.


Selective ablation of Ppp1cc gene in testicular germ cells causes oligo-teratozoospermia and infertility in mice.

Sinha N, Puri P, Nairn AC, Vijayaraghavan S.

Biol Reprod. 2013 Nov 27;89(5):128. doi: 10.1095/biolreprod.113.110239. Print 2013 Nov.


Significant expression levels of transgenic PPP1CC2 in testis and sperm are required to overcome the male infertility phenotype of Ppp1cc null mice.

Sinha N, Pilder S, Vijayaraghavan S.

PLoS One. 2012;7(10):e47623. doi: 10.1371/journal.pone.0047623. Epub 2012 Oct 17.


Analysis of Ppp1cc-null mice suggests a role for PP1gamma2 in sperm morphogenesis.

Chakrabarti R, Kline D, Lu J, Orth J, Pilder S, Vijayaraghavan S.

Biol Reprod. 2007 Jun;76(6):992-1001. Epub 2007 Feb 14.


PPP1CC2 can form a kinase/phosphatase complex with the testis-specific proteins TSSK1 and TSKS in the mouse testis.

MacLeod G, Shang P, Booth GT, Mastropaolo LA, Manafpoursakha N, Vogl AW, Varmuza S.

Reproduction. 2013 Nov 16;147(1):1-12. doi: 10.1530/REP-13-0224. Print 2014 Jan.


Construction and analysis of a human testis/sperm-enriched interaction network: Unraveling the PPP1CC2 interactome.

Silva JV, Yoon S, De Bock PJ, Goltsev AV, Gevaert K, Mendes JF, Fardilha M.

Biochim Biophys Acta. 2017 Feb;1861(2):375-385. doi: 10.1016/j.bbagen.2016.11.041. Epub 2016 Nov 30.


Disruption of the murine dynein light chain gene Tcte3-3 results in asthenozoospermia.

Rashid S, Grzmil P, Drenckhahn JD, Meinhardt A, Adham I, Engel W, Neesen J.

Reproduction. 2010 Jan;139(1):99-111. doi: 10.1530/REP-09-0243.


Phosphoprotein phosphatase 1 complexes in spermatogenesis.

Silva JV, Freitas MJ, Fardilha M.

Curr Mol Pharmacol. 2014;7(2):136-46. Review.


Infertility in male transgenic mice: disruption of sperm development by HSV-tk expression in postmeiotic germ cells.

Braun RE, Lo D, Pinkert CA, Widera G, Flavell RA, Palmiter RD, Brinster RL.

Biol Reprod. 1990 Oct;43(4):684-93.


Hormonal and genetic control of germ cell apoptosis in the testis.

Sinha Hikim AP, Swerdloff RS.

Rev Reprod. 1999 Jan;4(1):38-47. Review.


Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development.

Suzuki A, Tsuda M, Saga Y.

Development. 2007 Jan;134(1):77-83. Epub 2006 Nov 30.


Coiled-coil domain containing 42 (Ccdc42) is necessary for proper sperm development and male fertility in the mouse.

Pasek RC, Malarkey E, Berbari NF, Sharma N, Kesterson RA, Tres LL, Kierszenbaum AL, Yoder BK.

Dev Biol. 2016 Apr 15;412(2):208-18. doi: 10.1016/j.ydbio.2016.01.042. Epub 2016 Mar 3.


Germ cell-specific disruption of the Meig1 gene causes impaired spermiogenesis in mice.

Teves ME, Jha KN, Song J, Nagarkatti-Gude DR, Herr JC, Foster JA, Strauss JF 3rd, Zhang Z.

Andrology. 2013 Jan;1(1):37-46. doi: 10.1111/j.2047-2927.2012.00001.x. Epub 2012 Aug 30.


Transgenic expression of testis-specific poly(A) polymerase TPAP in wild-type and TPAP-deficient mice.

Zhuang T, Kashiwabara S, Noguchi J, Baba T.

J Reprod Dev. 2004 Apr;50(2):207-13.


Reduced urea flux across the blood-testis barrier and early maturation in the male reproductive system in UT-B-null mice.

Guo L, Zhao D, Song Y, Meng Y, Zhao H, Zhao X, Yang B.

Am J Physiol Cell Physiol. 2007 Jul;293(1):C305-12. Epub 2007 May 2.


Low-affinity nerve growth factor receptor is expressed during testicular morphogenesis and in germ cells at specific stages of spermatogenesis.

Russo MA, Odorisio T, Fradeani A, Rienzi L, De Felici M, Cattaneo A, Siracusa G.

Mol Reprod Dev. 1994 Feb;37(2):157-66.


CMV-driven expression of green fluorescent protein (GFP) in male germ cells of transgenic mice and its effect on fertility.

Villuendas G, Gutiérrez-Adán A, Jiménez A, Rojo C, Roldán ER, Pintado B.

Int J Androl. 2001 Oct;24(5):300-5.


New candidate targets of protein phosphatase-1c-gamma-2 in mouse testis revealed by a differential phosphoproteome analysis.

Henderson H, Macleod G, Hrabchak C, Varmuza S.

Int J Androl. 2011 Aug;34(4):339-51. doi: 10.1111/j.1365-2605.2010.01085.x. Epub 2010 Jul 1.


Isolation and properties of Gas8, a growth arrest-specific gene regulated during male gametogenesis to produce a protein associated with the sperm motility apparatus.

Yeh SD, Chen YJ, Chang AC, Ray R, She BR, Lee WS, Chiang HS, Cohen SN, Lin-Chao S.

J Biol Chem. 2002 Feb 22;277(8):6311-7. Epub 2002 Jan 7.

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