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Items: 1 to 20 of 79

1.

Foxa2-dependent hepatic gene regulatory networks depend on physiological state.

Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH.

Physiol Genomics. 2009 Jul 9;38(2):186-95. doi: 10.1152/physiolgenomics.90376.2008. Epub 2009 May 5.

2.

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.

Bochkis IM, Rubins NE, White P, Furth EE, Friedman JR, Kaestner KH.

Nat Med. 2008 Aug;14(8):828-36. doi: 10.1038/nm.1853. Epub 2008 Jul 27.

3.
4.

Cis-regulatory modules in the mammalian liver: composition depends on strength of Foxa2 consensus site.

Tuteja G, Jensen ST, White P, Kaestner KH.

Nucleic Acids Res. 2008 Jul;36(12):4149-57. doi: 10.1093/nar/gkn366. Epub 2008 Jun 13.

5.

Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencing.

Wederell ED, Bilenky M, Cullum R, Thiessen N, Dagpinar M, Delaney A, Varhol R, Zhao Y, Zeng T, Bernier B, Ingham M, Hirst M, Robertson G, Marra MA, Jones S, Hoodless PA.

Nucleic Acids Res. 2008 Aug;36(14):4549-64. doi: 10.1093/nar/gkn382. Epub 2008 Jul 8.

6.

FOXA2 regulates a network of genes involved in critical functions of human intestinal epithelial cells.

Gosalia N, Yang R, Kerschner JL, Harris A.

Physiol Genomics. 2015 Jul;47(7):290-7. doi: 10.1152/physiolgenomics.00024.2015. Epub 2015 Apr 28.

7.

Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.

Johnson ME, Schug J, Wells AD, Kaestner KH, Grant SF.

J Clin Endocrinol Metab. 2014 Aug;99(8):E1580-5. doi: 10.1210/jc.2013-4503. Epub 2014 May 30.

8.

Strategies to fine-map genetic associations with lipid levels by combining epigenomic annotations and liver-specific transcription profiles.

Lo KS, Vadlamudi S, Fogarty MP, Mohlke KL, Lettre G.

Genomics. 2014 Aug;104(2):105-12. doi: 10.1016/j.ygeno.2014.04.006. Epub 2014 Jul 2.

9.

Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism.

von Meyenn F, Porstmann T, Gasser E, Selevsek N, Schmidt A, Aebersold R, Stoffel M.

Cell Metab. 2013 Mar 5;17(3):436-47. doi: 10.1016/j.cmet.2013.01.014. Epub 2013 Feb 14.

10.

Metformin impairs systemic bile acid homeostasis through regulating SIRT1 protein levels.

Chen Q, Yang X, Zhang H, Kong X, Yao L, Cui X, Zou Y, Fang F, Yang J, Chang Y.

Biochim Biophys Acta. 2017 Jan;1864(1):101-112. doi: 10.1016/j.bbamcr.2016.10.020. Epub 2016 Nov 3.

11.

Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.

Su N, Thiaville MM, Awad K, Gjymishka A, Brant JO, Yang TP, Kilberg MS.

Hepatology. 2009 Jul;50(1):282-90. doi: 10.1002/hep.22971.

12.

Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.

Yu X, Gupta A, Wang Y, Suzuki K, Mirosevich J, Orgebin-Crist MC, Matusik RJ.

Ann N Y Acad Sci. 2005 Dec;1061:77-93.

PMID:
16467259
13.

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

Tamplin OJ, Cox BJ, Rossant J.

Dev Biol. 2011 Dec 15;360(2):415-25. doi: 10.1016/j.ydbio.2011.10.002. Epub 2011 Oct 8.

14.

Welcoming Foxa2 in the bile acid entourage.

Moschetta A.

Cell Metab. 2008 Oct;8(4):276-8. doi: 10.1016/j.cmet.2008.09.009.

15.

Species-specific strategies underlying conserved functions of metabolic transcription factors.

Soccio RE, Tuteja G, Everett LJ, Li Z, Lazar MA, Kaestner KH.

Mol Endocrinol. 2011 Apr;25(4):694-706. doi: 10.1210/me.2010-0454. Epub 2011 Feb 3.

16.

Foxa2 may modulate hepatic apoptosis through the cIAP1 pathway.

Wang K, Brems JJ, Gamelli RL, Holterman AX.

Cell Signal. 2013 Apr;25(4):867-74. doi: 10.1016/j.cellsig.2012.12.012. Epub 2012 Dec 27.

PMID:
23275033
17.

Identification of DNA-dependent protein kinase as a cofactor for the forkhead transcription factor FoxA2.

Nock A, Ascano JM, Jones T, Barrero MJ, Sugiyama N, Tomita M, Ishihama Y, Malik S.

J Biol Chem. 2009 Jul 24;284(30):19915-26. doi: 10.1074/jbc.M109.016295. Epub 2009 May 28.

18.

Hepatocyte nuclear factor 4alpha coordinates a transcription factor network regulating hepatic fatty acid metabolism.

Martinez-Jimenez CP, Kyrmizi I, Cardot P, Gonzalez FJ, Talianidis I.

Mol Cell Biol. 2010 Feb;30(3):565-77. doi: 10.1128/MCB.00927-09. Epub 2009 Nov 23.

19.

Foxa2 acts as a co-activator potentiating expression of the Nurr1-induced DA phenotype via epigenetic regulation.

Yi SH, He XB, Rhee YH, Park CH, Takizawa T, Nakashima K, Lee SH.

Development. 2014 Feb;141(4):761-72. doi: 10.1242/dev.095802.

20.

Genome-wide relationship between histone H3 lysine 4 mono- and tri-methylation and transcription factor binding.

Robertson AG, Bilenky M, Tam A, Zhao Y, Zeng T, Thiessen N, Cezard T, Fejes AP, Wederell ED, Cullum R, Euskirchen G, Krzywinski M, Birol I, Snyder M, Hoodless PA, Hirst M, Marra MA, Jones SJ.

Genome Res. 2008 Dec;18(12):1906-17. doi: 10.1101/gr.078519.108. Epub 2008 Sep 11.

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