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Items: 1 to 20 of 138

1.

Activation of the liver X receptor stimulates trans-intestinal excretion of plasma cholesterol.

van der Veen JN, van Dijk TH, Vrins CL, van Meer H, Havinga R, Bijsterveld K, Tietge UJ, Groen AK, Kuipers F.

J Biol Chem. 2009 Jul 17;284(29):19211-9. doi: 10.1074/jbc.M109.014860. Epub 2009 May 5.

2.

Stimulation of cholesterol excretion by the liver X receptor agonist requires ATP-binding cassette transporters G5 and G8.

Yu L, York J, von Bergmann K, Lutjohann D, Cohen JC, Hobbs HH.

J Biol Chem. 2003 May 2;278(18):15565-70. Epub 2003 Feb 22.

3.

Abcg5/8 independent biliary cholesterol excretion in Atp8b1-deficient mice.

Groen A, Kunne C, Jongsma G, van den Oever K, Mok KS, Petruzzelli M, Vrins CL, Bull L, Paulusma CC, Oude Elferink RP.

Gastroenterology. 2008 Jun;134(7):2091-100. doi: 10.1053/j.gastro.2008.02.097. Epub 2008 Mar 8.

PMID:
18466903
4.

Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.

Kruit JK, Plösch T, Havinga R, Boverhof R, Groot PH, Groen AK, Kuipers F.

Gastroenterology. 2005 Jan;128(1):147-56.

PMID:
15633131
5.

Reduction of cholesterol absorption by dietary plant sterols and stanols in mice is independent of the Abcg5/8 transporter.

Plösch T, Kruit JK, Bloks VW, Huijkman NC, Havinga R, Duchateau GS, Lin Y, Kuipers F.

J Nutr. 2006 Aug;136(8):2135-40.

6.

Pharmacological LXR activation reduces presence of SR-B1 in liver membranes contributing to LXR-mediated induction of HDL-cholesterol.

Grefhorst A, Oosterveer MH, Brufau G, Boesjes M, Kuipers F, Groen AK.

Atherosclerosis. 2012 Jun;222(2):382-9. doi: 10.1016/j.atherosclerosis.2012.02.014. Epub 2012 Mar 3.

7.

A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.

de Vogel-van den Bosch HM, de Wit NJ, Hooiveld GJ, Vermeulen H, van der Veen JN, Houten SM, Kuipers F, Müller M, van der Meer R.

Am J Physiol Gastrointest Liver Physiol. 2008 May;294(5):G1171-80. doi: 10.1152/ajpgi.00360.2007. Epub 2008 Mar 20.

8.

Abcg5/Abcg8-independent pathways contribute to hepatobiliary cholesterol secretion in mice.

Plösch T, van der Veen JN, Havinga R, Huijkman NC, Bloks VW, Kuipers F.

Am J Physiol Gastrointest Liver Physiol. 2006 Sep;291(3):G414-23. Epub 2006 Apr 13.

9.

Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.

Plösch T, Bloks VW, Terasawa Y, Berdy S, Siegler K, Van Der Sluijs F, Kema IP, Groen AK, Shan B, Kuipers F, Schwarz M.

Gastroenterology. 2004 Jan;126(1):290-300. Erratum in: Gastroenterology. 2004 Mar;126(3):944. Schwartz Margrit [corrected to Schwarz Margrit].

PMID:
14699507
10.

LXR driven induction of HDL-cholesterol is independent of intestinal cholesterol absorption and ABCA1 protein expression.

Kannisto K, Gåfvels M, Jiang ZY, Slätis K, Hu X, Jorns C, Steffensen KR, Eggertsen G.

Lipids. 2014 Jan;49(1):71-83. doi: 10.1007/s11745-013-3853-8. Epub 2013 Oct 27.

PMID:
24163219
11.

Relation between hepatic expression of ATP-binding cassette transporters G5 and G8 and biliary cholesterol secretion in mice.

Kosters A, Frijters RJ, Schaap FG, Vink E, Plösch T, Ottenhoff R, Jirsa M, De Cuyper IM, Kuipers F, Groen AK.

J Hepatol. 2003 Jun;38(6):710-6.

PMID:
12763362
12.

Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.

Plōsch T, Kok T, Bloks VW, Smit MJ, Havinga R, Chimini G, Groen AK, Kuipers F.

J Biol Chem. 2002 Sep 13;277(37):33870-7. Epub 2002 Jul 8.

13.

Studies on the cholesterol-free mouse: strong activation of LXR-regulated hepatic genes when replacing cholesterol with desmosterol.

Heverin M, Meaney S, Brafman A, Shafir M, Olin M, Shafaati M, von Bahr S, Larsson L, Lövgren-Sandblom A, Diczfalusy U, Parini P, Feinstein E, Björkhem I.

Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2191-7. Epub 2007 Aug 30.

14.

Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR.

Khovidhunkit W, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR.

J Lipid Res. 2003 Sep;44(9):1728-36. Epub 2003 Jun 1.

15.

Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

Calpe-Berdiel L, Rotllan N, Fiévet C, Roig R, Blanco-Vaca F, Escolà-Gil JC.

J Lipid Res. 2008 Sep;49(9):1904-11. doi: 10.1194/jlr.M700470-JLR200. Epub 2008 May 28.

16.

Hepatic SR-BI, not endothelial lipase, expression determines biliary cholesterol secretion in mice.

Wiersma H, Gatti A, Nijstad N, Kuipers F, Tietge UJ.

J Lipid Res. 2009 Aug;50(8):1571-80. doi: 10.1194/jlr.M800434-JLR200. Epub 2009 Feb 28.

17.

Scavenger receptor class B type I mediates biliary cholesterol secretion independent of ATP-binding cassette transporter g5/g8 in mice.

Wiersma H, Gatti A, Nijstad N, Oude Elferink RP, Kuipers F, Tietge UJ.

Hepatology. 2009 Oct;50(4):1263-72. doi: 10.1002/hep.23112.

PMID:
19637290
18.

Liver-specific induction of Abcg5 and Abcg8 stimulates reverse cholesterol transport in response to ezetimibe treatment.

Altemus JB, Patel SB, Sehayek E.

Metabolism. 2014 Oct;63(10):1334-41. doi: 10.1016/j.metabol.2014.06.014. Epub 2014 Jun 22.

PMID:
25060694
19.

Hepatic ABCG5 and ABCG8 overexpression increases hepatobiliary sterol transport but does not alter aortic atherosclerosis in transgenic mice.

Wu JE, Basso F, Shamburek RD, Amar MJ, Vaisman B, Szakacs G, Joyce C, Tansey T, Freeman L, Paigen BJ, Thomas F, Brewer HB Jr, Santamarina-Fojo S.

J Biol Chem. 2004 May 28;279(22):22913-25. Epub 2004 Mar 25.

20.

Biliary sterol secretion is required for functional in vivo reverse cholesterol transport in mice.

Nijstad N, Gautier T, Briand F, Rader DJ, Tietge UJ.

Gastroenterology. 2011 Mar;140(3):1043-51. doi: 10.1053/j.gastro.2010.11.055. Epub 2010 Dec 4.

PMID:
21134376

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