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Items: 1 to 20 of 74

1.

Alpha5beta1-integrin controls ebolavirus entry by regulating endosomal cathepsins.

Schornberg KL, Shoemaker CJ, Dube D, Abshire MY, Delos SE, Bouton AH, White JM.

Proc Natl Acad Sci U S A. 2009 May 12;106(19):8003-8. doi: 10.1073/pnas.0807578106. Epub 2009 Apr 28.

2.

Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein.

Schornberg K, Matsuyama S, Kabsch K, Delos S, Bouton A, White J.

J Virol. 2006 Apr;80(8):4174-8.

3.

Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection.

Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM.

Science. 2005 Jun 10;308(5728):1643-5. Epub 2005 Apr 14.

4.

Cathepsin B & L are not required for ebola virus replication.

Marzi A, Reinheckel T, Feldmann H.

PLoS Negl Trop Dis. 2012;6(12):e1923. doi: 10.1371/journal.pntd.0001923. Epub 2012 Dec 6.

5.

Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.

Kaletsky RL, Simmons G, Bates P.

J Virol. 2007 Dec;81(24):13378-84. Epub 2007 Oct 10.

6.

A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alter its protease dependence during cell entry.

Wong AC, Sandesara RG, Mulherkar N, Whelan SP, Chandran K.

J Virol. 2010 Jan;84(1):163-75. doi: 10.1128/JVI.01832-09.

7.

Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration.

Kharitidi D, Apaja PM, Manteghi S, Suzuki K, Malitskaya E, Roldan A, Gingras MC, Takagi J, Lukacs GL, Pause A.

Cell Rep. 2015 Oct 20;13(3):599-609. doi: 10.1016/j.celrep.2015.09.024. Epub 2015 Oct 8.

8.

Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion.

Bale S, Liu T, Li S, Wang Y, Abelson D, Fusco M, Woods VL Jr, Saphire EO.

PLoS Negl Trop Dis. 2011 Nov;5(11):e1395. doi: 10.1371/journal.pntd.0001395. Epub 2011 Nov 15.

9.

Annexin A6 and Late Endosomal Cholesterol Modulate Integrin Recycling and Cell Migration.

García-Melero A, Reverter M, Hoque M, Meneses-Salas E, Koese M, Conway JR, Johnsen CH, Alvarez-Guaita A, Morales-Paytuvi F, Elmaghrabi YA, Pol A, Tebar F, Murray RZ, Timpson P, Enrich C, Grewal T, Rentero C.

J Biol Chem. 2016 Jan 15;291(3):1320-35. doi: 10.1074/jbc.M115.683557. Epub 2015 Nov 17.

10.

Chinese hamster ovary cell lines selected for resistance to ebolavirus glycoprotein mediated infection are defective for NPC1 expression.

Haines KM, Vande Burgt NH, Francica JR, Kaletsky RL, Bates P.

Virology. 2012 Oct 10;432(1):20-8. doi: 10.1016/j.virol.2012.05.018. Epub 2012 Jun 21.

11.

Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes.

Lobert VH, Brech A, Pedersen NM, Wesche J, Oppelt A, Malerød L, Stenmark H.

Dev Cell. 2010 Jul 20;19(1):148-59. doi: 10.1016/j.devcel.2010.06.010.

12.

Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change.

Brecher M, Schornberg KL, Delos SE, Fusco ML, Saphire EO, White JM.

J Virol. 2012 Jan;86(1):364-72. doi: 10.1128/JVI.05708-11. Epub 2011 Oct 26.

13.

Biochemical and structural characterization of cathepsin L-processed Ebola virus glycoprotein: implications for viral entry and immunogenicity.

Hood CL, Abraham J, Boyington JC, Leung K, Kwong PD, Nabel GJ.

J Virol. 2010 Mar;84(6):2972-82. doi: 10.1128/JVI.02151-09. Epub 2010 Jan 6.

14.
15.

Ebolavirus delta-peptide immunoadhesins inhibit marburgvirus and ebolavirus cell entry.

Radoshitzky SR, Warfield KL, Chi X, Dong L, Kota K, Bradfute SB, Gearhart JD, Retterer C, Kranzusch PJ, Misasi JN, Hogenbirk MA, Wahl-Jensen V, Volchkov VE, Cunningham JM, Jahrling PB, Aman MJ, Bavari S, Farzan M, Kuhn JH.

J Virol. 2011 Sep;85(17):8502-13. doi: 10.1128/JVI.02600-10. Epub 2011 Jun 22.

16.

Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step.

Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D'Souza RS, Casanova JE, White JM.

J Virol. 2015 Mar;89(5):2931-43. doi: 10.1128/JVI.03398-14. Epub 2014 Dec 31.

17.

Rotaviruses reach late endosomes and require the cation-dependent mannose-6-phosphate receptor and the activity of cathepsin proteases to enter the cell.

Díaz-Salinas MA, Silva-Ayala D, López S, Arias CF.

J Virol. 2014 Apr;88(8):4389-402. doi: 10.1128/JVI.03457-13. Epub 2014 Feb 5.

18.

Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins.

Roberts MS, Woods AJ, Dale TC, Van Der Sluijs P, Norman JC.

Mol Cell Biol. 2004 Feb;24(4):1505-15.

19.

Ebola virus glycoprotein 1: identification of residues important for binding and postbinding events.

Brindley MA, Hughes L, Ruiz A, McCray PB Jr, Sanchez A, Sanders DA, Maury W.

J Virol. 2007 Jul;81(14):7702-9. Epub 2007 May 2.

20.

Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcgamma receptors.

Driessen C, Lennon-Duménil AM, Ploegh HL.

Eur J Immunol. 2001 May;31(5):1592-601.

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