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Items: 1 to 20 of 174


FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds.

Zhang Z, Verheyden JM, Hassell JA, Sun X.

Dev Cell. 2009 Apr;16(4):607-13. doi: 10.1016/j.devcel.2009.02.008.


Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.

Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP.

Dev Cell. 2009 Apr;16(4):600-6. doi: 10.1016/j.devcel.2009.02.005.


Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.

Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE.

Dev Cell. 2012 Feb 14;22(2):459-67. doi: 10.1016/j.devcel.2011.12.010.


Preaxial polydactyly: interactions among ETV, TWIST1 and HAND2 control anterior-posterior patterning of the limb.

Zhang Z, Sui P, Dong A, Hassell J, Cserjesi P, Chen YT, Behringer RR, Sun X.

Development. 2010 Oct;137(20):3417-26. doi: 10.1242/dev.051789. Epub 2010 Sep 8.


Manifestation of the limb prepattern: limb development in the absence of sonic hedgehog function.

Chiang C, Litingtung Y, Harris MP, Simandl BK, Li Y, Beachy PA, Fallon JF.

Dev Biol. 2001 Aug 15;236(2):421-35.


GATA6 is a crucial regulator of Shh in the limb bud.

Kozhemyakina E, Ionescu A, Lassar AB.

PLoS Genet. 2014 Jan;10(1):e1004072. doi: 10.1371/journal.pgen.1004072. Epub 2014 Jan 9.


Sonic hedgehog is not required for polarising activity in the Doublefoot mutant mouse limb bud.

Hayes C, Brown JM, Lyon MF, Morriss-Kay GM.

Development. 1998 Feb;125(3):351-7.


SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling.

Probst S, Kraemer C, Demougin P, Sheth R, Martin GR, Shiratori H, Hamada H, Iber D, Zeller R, Zuniga A.

Development. 2011 May;138(10):1913-23. doi: 10.1242/dev.063966. Epub 2011 Apr 6.


Progression of vertebrate limb development through SHH-mediated counteraction of GLI3.

te Welscher P, Zuniga A, Kuijper S, Drenth T, Goedemans HJ, Meijlink F, Zeller R.

Science. 2002 Oct 25;298(5594):827-30. Epub 2002 Sep 5.


The limb bud Shh-Fgf feedback loop is terminated by expansion of former ZPA cells.

Scherz PJ, Harfe BD, McMahon AP, Tabin CJ.

Science. 2004 Jul 16;305(5682):396-9.


Shh, Bmp-2 and Hoxd-13 gene expression in chick limb bud cells in culture.

Kimura J, Ide H.

Dev Growth Differ. 1998 Aug;40(4):457-64.


Twist1 activity thresholds define multiple functions in limb development.

Krawchuk D, Weiner SJ, Chen YT, Lu BC, Costantini F, Behringer RR, Laufer E.

Dev Biol. 2010 Nov 1;347(1):133-46. doi: 10.1016/j.ydbio.2010.08.015. Epub 2010 Aug 21.


A BMP-Shh negative-feedback loop restricts Shh expression during limb development.

Bastida MF, Sheth R, Ros MA.

Development. 2009 Nov;136(22):3779-89. doi: 10.1242/dev.036418.


Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice.

Akiyama H, Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B.

Matrix Biol. 2007 May;26(4):224-33. Epub 2006 Dec 8.


Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin.

Li J, Wang Q, Cui Y, Yang X, Li Y, Zhang X, Qiu M, Zhang Z, Zhang Z.

PLoS One. 2015 May 22;10(5):e0128006. doi: 10.1371/journal.pone.0128006. eCollection 2015.


Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin.

Capdevila J, Tsukui T, Rodríquez Esteban C, Zappavigna V, Izpisúa Belmonte JC.

Mol Cell. 1999 Nov;4(5):839-49.


Distinct roles of Hand2 in initiating polarity and posterior Shh expression during the onset of mouse limb bud development.

Galli A, Robay D, Osterwalder M, Bao X, Bénazet JD, Tariq M, Paro R, Mackem S, Zeller R.

PLoS Genet. 2010 Apr 8;6(4):e1000901. doi: 10.1371/journal.pgen.1000901.


Conditional inactivation of Fgf4 reveals complexity of signalling during limb bud development.

Sun X, Lewandoski M, Meyers EN, Liu YH, Maxson RE Jr, Martin GR.

Nat Genet. 2000 May;25(1):83-6.


Evidence for genetic control of Sonic hedgehog by Gli3 in mouse limb development.

Büscher D, Bosse B, Heymer J, Rüther U.

Mech Dev. 1997 Mar;62(2):175-82.

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