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Items: 1 to 20 of 65

1.

miR-24-mediated downregulation of H2AX suppresses DNA repair in terminally differentiated blood cells.

Lal A, Pan Y, Navarro F, Dykxhoorn DM, Moreau L, Meire E, Bentwich Z, Lieberman J, Chowdhury D.

Nat Struct Mol Biol. 2009 May;16(5):492-8. doi: 10.1038/nsmb.1589. Epub 2009 Apr 19.

2.

MicroRNA-138 Regulates DNA Damage Response in Small Cell Lung Cancer Cells by Directly Targeting H2AX.

Yang H, Luo J, Liu Z, Zhou R, Luo H.

Cancer Invest. 2015 Apr;33(4):126-36. doi: 10.3109/07357907.2015.1006329. Epub 2015 Feb 20.

PMID:
25699650
3.

c-Fos-dependent miR-22 targets MDC1 and regulates DNA repair in terminally differentiated cells.

Lee JH, Park SJ, Kim SW, Hariharasudhan G, Jung SM, Jun S, Yong J, Jin You H.

Oncotarget. 2017 Jul 18;8(29):48204-48221. doi: 10.18632/oncotarget.18389.

4.

MicroRNA-138 modulates DNA damage response by repressing histone H2AX expression.

Wang Y, Huang JW, Li M, Cavenee WK, Mitchell PS, Zhou X, Tewari M, Furnari FB, Taniguchi T.

Mol Cancer Res. 2011 Aug;9(8):1100-11. doi: 10.1158/1541-7786.MCR-11-0007. Epub 2011 Jun 21.

5.

PP2A-B56ϵ complex is involved in dephosphorylation of γ-H2AX in the repair process of CPT-induced DNA double-strand breaks.

Li X, Nan A, Xiao Y, Chen Y, Lai Y.

Toxicology. 2015 May 4;331:57-65. doi: 10.1016/j.tox.2015.03.007. Epub 2015 Mar 12.

PMID:
25772433
6.

A critical role for histone H2AX in recruitment of repair factors to nuclear foci after DNA damage.

Paull TT, Rogakou EP, Yamazaki V, Kirchgessner CU, Gellert M, Bonner WM.

Curr Biol. 2000 Jul 27-Aug 10;10(15):886-95.

7.

Upregulation of miR-24 is associated with a decreased DNA damage response upon etoposide treatment in highly differentiated CD8(+) T cells sensitizing them to apoptotic cell death.

Brunner S, Herndler-Brandstetter D, Arnold CR, Wiegers GJ, Villunger A, Hackl M, Grillari J, Moreno-Villanueva M, Bürkle A, Grubeck-Loebenstein B.

Aging Cell. 2012 Aug;11(4):579-87. doi: 10.1111/j.1474-9726.2012.00819.x. Epub 2012 Apr 18.

8.

UV and genotoxic stress induce ATR relocalization in mouse spermatocytes.

Di Siena S, Campolo F, Rossi P, Jannini EA, Dolci S, Pellegrini M.

Int J Dev Biol. 2013;57(2-4):281-7. doi: 10.1387/ijdb.130039sd.

9.

MiR-23a regulates DNA damage repair and apoptosis in UVB-irradiated HaCaT cells.

Guo Z, Zhou B, Liu W, Xu Y, Wu D, Yin Z, Permatasari F, Luo D.

J Dermatol Sci. 2013 Jan;69(1):68-76. doi: 10.1016/j.jdermsci.2012.10.014. Epub 2012 Oct 30.

PMID:
23158364
10.
11.

Dose response and repair kinetics of gamma-H2AX foci induced by in vitro irradiation of whole blood and T-lymphocytes with X- and gamma-radiation.

Beels L, Werbrouck J, Thierens H.

Int J Radiat Biol. 2010 Sep;86(9):760-8. doi: 10.3109/09553002.2010.484479.

PMID:
20597840
12.

MicroRNA-7 inhibition rescues age-associated loss of epidermal growth factor receptor and hyaluronan-dependent differentiation in fibroblasts.

Midgley AC, Bowen T, Phillips AO, Steadman R.

Aging Cell. 2014 Apr;13(2):235-44. doi: 10.1111/acel.12167. Epub 2013 Nov 12.

13.

gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair.

Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J.

Mol Cell. 2005 Dec 9;20(5):801-9. Epub 2005 Nov 28.

14.
15.

Areca nut induces miR-23a and inhibits repair of DNA double-strand breaks by targeting FANCG.

Tsai YS, Lin CS, Chiang SL, Lee CH, Lee KW, Ko YC.

Toxicol Sci. 2011 Oct;123(2):480-90. doi: 10.1093/toxsci/kfr182. Epub 2011 Jul 12.

PMID:
21750350
16.

miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells.

He M, Lin Y, Tang Y, Liu Y, Zhou W, Li C, Sun G, Guo M.

Aging (Albany NY). 2016 Jul;8(7):1442-56. doi: 10.18632/aging.100998.

17.

Replication independent DNA double-strand break retention may prevent genomic instability.

Kongruttanachok N, Phuangphairoj C, Thongnak A, Ponyeam W, Rattanatanyong P, Pornthanakasem W, Mutirangura A.

Mol Cancer. 2010 Mar 31;9:70. doi: 10.1186/1476-4598-9-70.

18.

microRNA-383 impairs phosphorylation of H2AX by targeting PNUTS and inducing cell cycle arrest in testicular embryonal carcinoma cells.

Huang H, Tian H, Duan Z, Cao Y, Zhang XS, Sun F.

Cell Signal. 2014 May;26(5):903-11. doi: 10.1016/j.cellsig.2014.01.016. Epub 2014 Jan 22.

PMID:
24462707
19.

Depletion of intermediate filament protein Nestin, a target of microRNA-940, suppresses tumorigenesis by inducing spontaneous DNA damage accumulation in human nasopharyngeal carcinoma.

Ma J, Sun F, Li C, Zhang Y, Xiao W, Li Z, Pan Q, Zeng H, Xiao G, Yao K, Hong A, An J.

Cell Death Dis. 2014 Aug 14;5:e1377. doi: 10.1038/cddis.2014.293.

20.

The nuclear aryl hydocarbon receptor is involved in regulation of DNA repair and cell survival following treatment with ionizing radiation.

Dittmann KH, Rothmund MC, Paasch A, Mayer C, Fehrenbacher B, Schaller M, Frauenstein K, Fritsche E, Haarmann-Stemmann T, Braeuning A, Rodemann HP.

Toxicol Lett. 2016 Jan 5;240(1):122-9. doi: 10.1016/j.toxlet.2015.10.017. Epub 2015 Oct 28.

PMID:
26520184

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