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Items: 1 to 20 of 144

1.

Mitochondrial gene therapy augments mitochondrial physiology in a Parkinson's disease cell model.

Keeney PM, Quigley CK, Dunham LD, Papageorge CM, Iyer S, Thomas RR, Schwarz KM, Trimmer PA, Khan SM, Portell FR, Bergquist KE, Bennett JP Jr.

Hum Gene Ther. 2009 Aug;20(8):897-907. doi: 10.1089/hum.2009.023.

2.

Recombinant mitochondrial transcription factor A with N-terminal mitochondrial transduction domain increases respiration and mitochondrial gene expression.

Iyer S, Thomas RR, Portell FR, Dunham LD, Quigley CK, Bennett JP Jr.

Mitochondrion. 2009 Jun;9(3):196-203. doi: 10.1016/j.mito.2009.01.012. Epub 2009 Feb 4.

3.

Cybrid models of Parkinson's disease show variable mitochondrial biogenesis and genotype-respiration relationships.

Keeney PM, Dunham LD, Quigley CK, Morton SL, Bergquist KE, Bennett JP Jr.

Exp Neurol. 2009 Dec;220(2):374-82. doi: 10.1016/j.expneurol.2009.09.025. Epub 2009 Oct 6.

4.

ERK-mediated phosphorylation of TFAM downregulates mitochondrial transcription: implications for Parkinson's disease.

Wang KZ, Zhu J, Dagda RK, Uechi G, Cherra SJ 3rd, Gusdon AM, Balasubramani M, Chu CT.

Mitochondrion. 2014 Jul;17:132-40. doi: 10.1016/j.mito.2014.04.008. Epub 2014 Apr 24.

5.

High mitochondrial DNA copy number and bioenergetic function are associated with tumor invasion of esophageal squamous cell carcinoma cell lines.

Lin CS, Lee HT, Lee SY, Shen YA, Wang LS, Chen YJ, Wei YH.

Int J Mol Sci. 2012;13(9):11228-46. doi: 10.3390/ijms130911228. Epub 2012 Sep 10.

6.

Impaired complex-I mitochondrial biogenesis in Parkinson disease frontal cortex.

Thomas RR, Keeney PM, Bennett JP.

J Parkinsons Dis. 2012;2(1):67-76. doi: 10.3233/JPD-2012-11074.

PMID:
23939409
7.

Relationships among molecular genetic and respiratory properties of Parkinson's disease cybrid cells show similarities to Parkinson's brain tissues.

Borland MK, Mohanakumar KP, Rubinstein JD, Keeney PM, Xie J, Capaldi R, Dunham LD, Trimmer PA, Bennett JP Jr.

Biochim Biophys Acta. 2009 Jan;1792(1):68-74. doi: 10.1016/j.bbadis.2008.09.014. Epub 2008 Oct 10.

8.

Architectural role of mitochondrial transcription factor A in maintenance of human mitochondrial DNA.

Kanki T, Ohgaki K, Gaspari M, Gustafsson CM, Fukuoh A, Sasaki N, Hamasaki N, Kang D.

Mol Cell Biol. 2004 Nov;24(22):9823-34.

9.
10.

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number.

Campbell CT, Kolesar JE, Kaufman BA.

Biochim Biophys Acta. 2012 Sep-Oct;1819(9-10):921-9. doi: 10.1016/j.bbagrm.2012.03.002. Epub 2012 Mar 21. Review.

PMID:
22465614
11.

Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells.

Piao Y, Kim HG, Oh MS, Pak YK.

Biochim Biophys Acta. 2012 May;1820(5):577-85. doi: 10.1016/j.bbagen.2011.08.007. Epub 2011 Aug 11.

PMID:
21856379
12.

Role of Mitochondrial DNA Copy Number Alteration in Human Renal Cell Carcinoma.

Lin CS, Lee HT, Lee MH, Pan SC, Ke CY, Chiu AW, Wei YH.

Int J Mol Sci. 2016 May 25;17(6). pii: E814. doi: 10.3390/ijms17060814.

13.

Interaction of human mitochondrial transcription factor A in mitochondria: its involvement in the dynamics of mitochondrial DNA nucleoids.

Kasashima K, Endo H.

Genes Cells. 2015 Dec;20(12):1017-27. doi: 10.1111/gtc.12306. Epub 2015 Oct 7.

14.

mtDNA makes a U-turn for the mitochondrial nucleoid.

Kukat C, Larsson NG.

Trends Cell Biol. 2013 Sep;23(9):457-63. doi: 10.1016/j.tcb.2013.04.009. Epub 2013 May 27. Review.

PMID:
23721879
15.

MiR-144-3p and Its Target Gene β-Amyloid Precursor Protein Regulate 1-Methyl-4-Phenyl-1,2-3,6-Tetrahydropyridine-Induced Mitochondrial Dysfunction.

Li K, Zhang J, Ji C, Wang L.

Mol Cells. 2016 Jul;39(7):543-9. doi: 10.14348/molcells.2016.0050. Epub 2016 Jun 21.

16.

Mitochondrial transcription factor A regulation of mitochondrial degeneration in experimental diabetic neuropathy.

Chandrasekaran K, Anjaneyulu M, Inoue T, Choi J, Sagi AR, Chen C, Ide T, Russell JW.

Am J Physiol Endocrinol Metab. 2015 Jul 15;309(2):E132-41. doi: 10.1152/ajpendo.00620.2014. Epub 2015 May 5.

17.

Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease.

Lu B, Lee J, Nie X, Li M, Morozov YI, Venkatesh S, Bogenhagen DF, Temiakov D, Suzuki CK.

Mol Cell. 2013 Jan 10;49(1):121-32. doi: 10.1016/j.molcel.2012.10.023. Epub 2012 Nov 29.

18.

Mutant Twinkle increases dopaminergic neurodegeneration, mtDNA deletions and modulates Parkin expression.

Song L, Shan Y, Lloyd KC, Cortopassi GA.

Hum Mol Genet. 2012 Dec 1;21(23):5147-58. doi: 10.1093/hmg/dds365. Epub 2012 Sep 4.

19.

Human mitochondrial transcription factor A is required for the segregation of mitochondrial DNA in cultured cells.

Kasashima K, Sumitani M, Endo H.

Exp Cell Res. 2011 Jan 15;317(2):210-20. doi: 10.1016/j.yexcr.2010.10.008. Epub 2010 Oct 15.

PMID:
20955698
20.

The C-terminal tail of mitochondrial transcription factor a markedly strengthens its general binding to DNA.

Ohgaki K, Kanki T, Fukuoh A, Kurisaki H, Aoki Y, Ikeuchi M, Kim SH, Hamasaki N, Kang D.

J Biochem. 2007 Feb;141(2):201-11. Epub 2006 Dec 13.

PMID:
17167045

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