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Items: 1 to 20 of 86

1.

AMP-activated protein kinase promotes human prostate cancer cell growth and survival.

Park HU, Suy S, Danner M, Dailey V, Zhang Y, Li H, Hyduke DR, Collins BT, Gagnon G, Kallakury B, Kumar D, Brown ML, Fornace A, Dritschilo A, Collins SP.

Mol Cancer Ther. 2009 Apr;8(4):733-41. doi: 10.1158/1535-7163.MCT-08-0631.

2.

Androgens regulate prostate cancer cell growth via an AMPK-PGC-1α-mediated metabolic switch.

Tennakoon JB, Shi Y, Han JJ, Tsouko E, White MA, Burns AR, Zhang A, Xia X, Ilkayeva OR, Xin L, Ittmann MM, Rick FG, Schally AV, Frigo DE.

Oncogene. 2014 Nov 6;33(45):5251-61. doi: 10.1038/onc.2013.463. Epub 2013 Nov 4.

3.

Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress.

Chhipa RR, Wu Y, Mohler JL, Ip C.

Cell Signal. 2010 Oct;22(10):1554-61. doi: 10.1016/j.cellsig.2010.05.024. Epub 2010 Jun 4.

4.

Activation of AMP-activated protein kinase by 3,3'-Diindolylmethane (DIM) is associated with human prostate cancer cell death in vitro and in vivo.

Chen D, Banerjee S, Cui QC, Kong D, Sarkar FH, Dou QP.

PLoS One. 2012;7(10):e47186. doi: 10.1371/journal.pone.0047186. Epub 2012 Oct 9.

5.

Inactivation of AMPK alters gene expression and promotes growth of prostate cancer cells.

Zhou J, Huang W, Tao R, Ibaragi S, Lan F, Ido Y, Wu X, Alekseyev YO, Lenburg ME, Hu GF, Luo Z.

Oncogene. 2009 May 7;28(18):1993-2002. doi: 10.1038/onc.2009.63. Epub 2009 Apr 6.

6.

Ionizing radiation activates AMP-activated kinase (AMPK): a target for radiosensitization of human cancer cells.

Sanli T, Rashid A, Liu C, Harding S, Bristow RG, Cutz JC, Singh G, Wright J, Tsakiridis T.

Int J Radiat Oncol Biol Phys. 2010 Sep 1;78(1):221-9. doi: 10.1016/j.ijrobp.2010.03.005. Epub 2010 Jul 7.

PMID:
20615625
7.

Carnosol, a dietary diterpene, displays growth inhibitory effects in human prostate cancer PC3 cells leading to G2-phase cell cycle arrest and targets the 5'-AMP-activated protein kinase (AMPK) pathway.

Johnson JJ, Syed DN, Heren CR, Suh Y, Adhami VM, Mukhtar H.

Pharm Res. 2008 Sep;25(9):2125-34. doi: 10.1007/s11095-008-9552-0. Epub 2008 Feb 21.

8.

Apoptotic cells activate AMP-activated protein kinase (AMPK) and inhibit epithelial cell growth without change in intracellular energy stores.

Patel VA, Massenburg D, Vujicic S, Feng L, Tang M, Litbarg N, Antoni A, Rauch J, Lieberthal W, Levine JS.

J Biol Chem. 2015 Sep 11;290(37):22352-69. doi: 10.1074/jbc.M115.667345. Epub 2015 Jul 16.

9.

AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia.

Chhipa RR, Wu Y, Ip C.

Cell Signal. 2011 Sep;23(9):1466-72. doi: 10.1016/j.cellsig.2011.04.008. Epub 2011 Apr 28.

10.

The effects of adiponectin and metformin on prostate and colon neoplasia involve activation of AMP-activated protein kinase.

Zakikhani M, Dowling RJ, Sonenberg N, Pollak MN.

Cancer Prev Res (Phila). 2008 Oct;1(5):369-75. doi: 10.1158/1940-6207.CAPR-08-0081. Erratum in: Cancer Prev Res (Phila Pa). 2009 Jan;2(1):95.

11.

Protein kinase C promotes apoptosis in LNCaP prostate cancer cells through activation of p38 MAPK and inhibition of the Akt survival pathway.

Tanaka Y, Gavrielides MV, Mitsuuchi Y, Fujii T, Kazanietz MG.

J Biol Chem. 2003 Sep 5;278(36):33753-62. Epub 2003 Jun 24.

12.
13.

The pentacyclic triterpenoid, plectranthoic acid, a novel activator of AMPK induces apoptotic death in prostate cancer cells.

Akhtar N, Syed DN, Khan MI, Adhami VM, Mirza B, Mukhtar H.

Oncotarget. 2016 Jan 26;7(4):3819-31. doi: 10.18632/oncotarget.6625.

14.
15.

Monascuspiloin induces apoptosis and autophagic cell death in human prostate cancer cells via the Akt and AMPK signaling pathways.

Chen RJ, Hung CM, Chen YL, Wu MD, Yuan GF, Wang YJ.

J Agric Food Chem. 2012 Jul 25;60(29):7185-93. doi: 10.1021/jf3016927. Epub 2012 Jul 13.

PMID:
22738037
16.

AMP-activated protein kinase activity is critical for hypoxia-inducible factor-1 transcriptional activity and its target gene expression under hypoxic conditions in DU145 cells.

Lee M, Hwang JT, Lee HJ, Jung SN, Kang I, Chi SG, Kim SS, Ha J.

J Biol Chem. 2003 Oct 10;278(41):39653-61. Epub 2003 Aug 4.

17.

Alternol exerts prostate-selective antitumor effects through modulations of the AMPK signaling pathway.

Yeung ED, Morrison A, Plumeri D, Wang J, Tong C, Yan X, Li J.

Prostate. 2012 Feb 1;72(2):165-72. doi: 10.1002/pros.21417. Epub 2011 May 2.

PMID:
21538425
18.

Vitamin D3 potentiates the growth inhibitory effects of metformin in DU145 human prostate cancer cells mediated by AMPK/mTOR signalling pathway.

Li HX, Gao JM, Liang JQ, Xi JM, Fu M, Wu YJ.

Clin Exp Pharmacol Physiol. 2015 Jun;42(6):711-7. doi: 10.1111/1440-1681.12409.

PMID:
25903858
20.

Ionizing radiation regulates the expression of AMP-activated protein kinase (AMPK) in epithelial cancer cells: modulation of cellular signals regulating cell cycle and survival.

Sanli T, Storozhuk Y, Linher-Melville K, Bristow RG, Laderout K, Viollet B, Wright J, Singh G, Tsakiridis T.

Radiother Oncol. 2012 Mar;102(3):459-65. doi: 10.1016/j.radonc.2011.11.014. Epub 2012 Jan 5.

PMID:
22225791

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