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Items: 1 to 20 of 78

1.

Severe acute respiratory syndrome coronavirus papain-like protease ubiquitin-like domain and catalytic domain regulate antagonism of IRF3 and NF-kappaB signaling.

Frieman M, Ratia K, Johnston RE, Mesecar AD, Baric RS.

J Virol. 2009 Jul;83(13):6689-705. doi: 10.1128/JVI.02220-08. Epub 2009 Apr 15.

2.

The SARS coronavirus papain like protease can inhibit IRF3 at a post activation step that requires deubiquitination activity.

Matthews K, Schäfer A, Pham A, Frieman M.

Virol J. 2014 Dec 7;11:209. doi: 10.1186/s12985-014-0209-9.

3.

Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling.

Sun L, Xing Y, Chen X, Zheng Y, Yang Y, Nichols DB, Clementz MA, Banach BS, Li K, Baker SC, Chen Z.

PLoS One. 2012;7(2):e30802. doi: 10.1371/journal.pone.0030802. Epub 2012 Feb 1.

4.

Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.

Clementz MA, Chen Z, Banach BS, Wang Y, Sun L, Ratia K, Baez-Santos YM, Wang J, Takayama J, Ghosh AK, Li K, Mesecar AD, Baker SC.

J Virol. 2010 May;84(9):4619-29. doi: 10.1128/JVI.02406-09. Epub 2010 Feb 24.

5.

The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds.

Báez-Santos YM, St John SE, Mesecar AD.

Antiviral Res. 2015 Mar;115:21-38. doi: 10.1016/j.antiviral.2014.12.015. Epub 2014 Dec 29. Review.

PMID:
25554382
6.

Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirus.

Devaraj SG, Wang N, Chen Z, Chen Z, Tseng M, Barretto N, Lin R, Peters CJ, Tseng CT, Baker SC, Li K.

J Biol Chem. 2007 Nov 2;282(44):32208-21. Epub 2007 Aug 30.

7.

Severe acute respiratory syndrome coronavirus papain-like protease suppressed alpha interferon-induced responses through downregulation of extracellular signal-regulated kinase 1-mediated signalling pathways.

Li SW, Lai CC, Ping JF, Tsai FJ, Wan L, Lin YJ, Kung SH, Lin CW.

J Gen Virol. 2011 May;92(Pt 5):1127-40. doi: 10.1099/vir.0.028936-0. Epub 2011 Jan 26.

PMID:
21270289
8.

Porcine Epidemic Diarrhea Virus 3C-Like Protease Regulates Its Interferon Antagonism by Cleaving NEMO.

Wang D, Fang L, Shi Y, Zhang H, Gao L, Peng G, Chen H, Li K, Xiao S.

J Virol. 2015 Dec 9;90(4):2090-101. doi: 10.1128/JVI.02514-15.

9.

Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like protease.

Yang X, Chen X, Bian G, Tu J, Xing Y, Wang Y, Chen Z.

J Gen Virol. 2014 Mar;95(Pt 3):614-26. doi: 10.1099/vir.0.059014-0. Epub 2013 Dec 20.

PMID:
24362959
10.

SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6.

Li SW, Wang CY, Jou YJ, Huang SH, Hsiao LH, Wan L, Lin YJ, Kung SH, Lin CW.

Int J Mol Sci. 2016 May 5;17(5). pii: E678. doi: 10.3390/ijms17050678.

11.

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex.

Chen X, Yang X, Zheng Y, Yang Y, Xing Y, Chen Z.

Protein Cell. 2014 May;5(5):369-81. doi: 10.1007/s13238-014-0026-3. Epub 2014 Mar 14.

12.

Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.

Ratia K, Kilianski A, Baez-Santos YM, Baker SC, Mesecar A.

PLoS Pathog. 2014 May 22;10(5):e1004113. doi: 10.1371/journal.ppat.1004113. eCollection 2014 May.

13.

The papain-like protease from the severe acute respiratory syndrome coronavirus is a deubiquitinating enzyme.

Lindner HA, Fotouhi-Ardakani N, Lytvyn V, Lachance P, Sulea T, Ménard R.

J Virol. 2005 Dec;79(24):15199-208.

14.

Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme.

Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5717-22. Epub 2006 Mar 31.

15.

MERS-CoV papain-like protease has deISGylating and deubiquitinating activities.

Mielech AM, Kilianski A, Baez-Santos YM, Mesecar AD, Baker SC.

Virology. 2014 Feb;450-451:64-70. doi: 10.1016/j.virol.2013.11.040. Epub 2013 Dec 22.

16.

Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition.

Han YS, Chang GG, Juo CG, Lee HJ, Yeh SH, Hsu JT, Chen X.

Biochemistry. 2005 Aug 2;44(30):10349-59.

PMID:
16042412
17.

Dynamic innate immune responses of human bronchial epithelial cells to severe acute respiratory syndrome-associated coronavirus infection.

Yoshikawa T, Hill TE, Yoshikawa N, Popov VL, Galindo CL, Garner HR, Peters CJ, Tseng CT.

PLoS One. 2010 Jan 15;5(1):e8729. doi: 10.1371/journal.pone.0008729.

18.

Bat severe acute respiratory syndrome-like coronavirus ORF3b homologues display different interferon antagonist activities.

Zhou P, Li H, Wang H, Wang LF, Shi Z.

J Gen Virol. 2012 Feb;93(Pt 2):275-81. doi: 10.1099/vir.0.033589-0. Epub 2011 Oct 19.

PMID:
22012463
19.

Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference.

Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB.

J Virol. 2015 Dec;89(23):11820-33. doi: 10.1128/JVI.02274-15. Epub 2015 Sep 16.

20.

Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonists.

Kopecky-Bromberg SA, Martínez-Sobrido L, Frieman M, Baric RA, Palese P.

J Virol. 2007 Jan;81(2):548-57. Epub 2006 Nov 15.

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