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Items: 1 to 20 of 78


Non-genetic origins of cell-to-cell variability in TRAIL-induced apoptosis.

Spencer SL, Gaudet S, Albeck JG, Burke JM, Sorger PK.

Nature. 2009 May 21;459(7245):428-32. doi: 10.1038/nature08012. Epub 2009 Apr 12.


Systems biology: When it is time to die.

Bastiaens P.

Nature. 2009 May 21;459(7245):334-5. doi: 10.1038/459334a. No abstract available.


Real time analysis of tumor necrosis factor-related apoptosis-inducing ligand/cycloheximide-induced caspase activities during apoptosis initiation.

Hellwig CT, Kohler BF, Lehtivarjo AK, Dussmann H, Courtney MJ, Prehn JH, Rehm M.

J Biol Chem. 2008 Aug 1;283(31):21676-85. doi: 10.1074/jbc.M802889200. Epub 2008 Jun 3.


Lupulone, a hop bitter acid, activates different death pathways involving apoptotic TRAIL-receptors, in human colon tumor cells and in their derived metastatic cells.

Lamy V, Roussi S, Chaabi M, Gossé F, Lobstein A, Raul F.

Apoptosis. 2008 Oct;13(10):1232-42. doi: 10.1007/s10495-008-0250-5.


Receptor-mediated endocytosis is not required for tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis.

Kohlhaas SL, Craxton A, Sun XM, Pinkoski MJ, Cohen GM.

J Biol Chem. 2007 Apr 27;282(17):12831-41. Epub 2007 Feb 27.


Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.

Ramp U, Caliskan E, Mahotka C, Krieg A, Heikaus S, Gabbert HE, Gerharz CD.

Br J Cancer. 2003 Jun 2;88(11):1800-7.


RRR-gamma-tocopherol induces human breast cancer cells to undergo apoptosis via death receptor 5 (DR5)-mediated apoptotic signaling.

Yu W, Park SK, Jia L, Tiwary R, Scott WW, Li J, Wang P, Simmons-Menchaca M, Sanders BG, Kline K.

Cancer Lett. 2008 Feb 8;259(2):165-76. Epub 2007 Nov 19.


Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis.

Unterkircher T, Cristofanon S, Vellanki SH, Nonnenmacher L, Karpel-Massler G, Wirtz CR, Debatin KM, Fulda S.

Clin Cancer Res. 2011 Jun 15;17(12):4019-30. doi: 10.1158/1078-0432.CCR-11-0075. Epub 2011 Apr 27.


Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP.

Bangert A, Cristofanon S, Eckhardt I, Abhari BA, Kolodziej S, Häcker S, Vellanki SH, Lausen J, Debatin KM, Fulda S.

Oncogene. 2012 Nov 1;31(44):4677-88. doi: 10.1038/onc.2011.614. Epub 2012 Jan 23.


Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand.

Mitsiades N, Poulaki V, Tseleni-Balafouta S, Koutras DA, Stamenkovic I.

Cancer Res. 2000 Aug 1;60(15):4122-9.


Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response.

Jiang CC, Chen LH, Gillespie S, Kiejda KA, Mhaidat N, Wang YF, Thorne R, Zhang XD, Hersey P.

Cancer Res. 2007 Jun 15;67(12):5880-8.


Imatinib enhances human melanoma cell susceptibility to TRAIL-induced cell death: Relationship to Bcl-2 family and caspase activation.

Hamaï A, Richon C, Meslin F, Faure F, Kauffmann A, Lecluse Y, Jalil A, Larue L, Avril MF, Chouaib S, Mehrpour M.

Oncogene. 2006 Dec 7;25(58):7618-34. Epub 2006 Sep 18. Erratum in: Oncogene. 2007 Feb 22;26(8):1256.


Differential responses of FLIPLong and FLIPShort-overexpressing human myeloid leukemia cells to TNF-alpha and TRAIL-initiated apoptotic signals.

Seal S, Hockenbery DM, Spaulding EY, Kiem HP, Abbassi N, Deeg HJ.

Exp Hematol. 2008 Dec;36(12):1660-72. doi: 10.1016/j.exphem.2008.07.012. Epub 2008 Oct 5.


The mitogen-activated protein kinase pathway can inhibit TRAIL-induced apoptosis by prohibiting association of truncated Bid with mitochondria.

Ortiz-Ferrón G, Tait SW, Robledo G, de Vries E, Borst J, López-Rivas A.

Cell Death Differ. 2006 Nov;13(11):1857-65. Epub 2006 Feb 17.


Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.

Psahoulia FH, Drosopoulos KG, Doubravska L, Andera L, Pintzas A.

Mol Cancer Ther. 2007 Sep;6(9):2591-9.

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