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Items: 1 to 20 of 113

1.

Blood-brain barrier breakdown-inducing astrocytic transformation: novel targets for the prevention of epilepsy.

Friedman A, Kaufer D, Heinemann U.

Epilepsy Res. 2009 Aug;85(2-3):142-9. doi: 10.1016/j.eplepsyres.2009.03.005. Epub 2009 Apr 11. Review.

2.

TGF-beta receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis.

Ivens S, Kaufer D, Flores LP, Bechmann I, Zumsteg D, Tomkins O, Seiffert E, Heinemann U, Friedman A.

Brain. 2007 Feb;130(Pt 2):535-47. Epub 2006 Nov 21.

PMID:
17121744
3.

Role of Blood-Brain Barrier Dysfunction in Epileptogenesis.

Friedman A, Heinemann U.

In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012.

4.

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: role of astroglia.

Kovács R, Heinemann U, Steinhäuser C.

Epilepsia. 2012 Nov;53 Suppl 6:53-9. doi: 10.1111/j.1528-1167.2012.03703.x. Review.

5.

Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction.

Weissberg I, Wood L, Kamintsky L, Vazquez O, Milikovsky DZ, Alexander A, Oppenheim H, Ardizzone C, Becker A, Frigerio F, Vezzani A, Buckwalter MS, Huguenard JR, Friedman A, Kaufer D.

Neurobiol Dis. 2015 Jun;78:115-25. doi: 10.1016/j.nbd.2015.02.029. Epub 2015 Mar 30.

6.

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy.

Heinemann U, Kaufer D, Friedman A.

Glia. 2012 Aug;60(8):1251-7. doi: 10.1002/glia.22311. Epub 2012 Feb 29. Review.

7.

Transcriptome profiling reveals TGF-beta signaling involvement in epileptogenesis.

Cacheaux LP, Ivens S, David Y, Lakhter AJ, Bar-Klein G, Shapira M, Heinemann U, Friedman A, Kaufer D.

J Neurosci. 2009 Jul 15;29(28):8927-35. doi: 10.1523/JNEUROSCI.0430-09.2009.

8.

Blood-brain barrier dysfunction in epileptogenesis of the temporal lobe.

Weissberg I, Reichert A, Heinemann U, Friedman A.

Epilepsy Res Treat. 2011;2011:143908. doi: 10.1155/2011/143908. Epub 2011 Jun 7.

9.

Losartan prevents acquired epilepsy via TGF-β signaling suppression.

Bar-Klein G, Cacheaux LP, Kamintsky L, Prager O, Weissberg I, Schoknecht K, Cheng P, Kim SY, Wood L, Heinemann U, Kaufer D, Friedman A.

Ann Neurol. 2014 Jun;75(6):864-75. doi: 10.1002/ana.24147. Epub 2014 May 28.

10.

Astrocytic dysfunction in epileptogenesis: consequence of altered potassium and glutamate homeostasis?

David Y, Cacheaux LP, Ivens S, Lapilover E, Heinemann U, Kaufer D, Friedman A.

J Neurosci. 2009 Aug 26;29(34):10588-99. doi: 10.1523/JNEUROSCI.2323-09.2009.

11.

Are you in or out? Leukocyte, ion, and neurotransmitter permeability across the epileptic blood-brain barrier.

Janigro D.

Epilepsia. 2012 Jun;53 Suppl 1:26-34. doi: 10.1111/j.1528-1167.2012.03472.x. Review.

12.

Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury.

Shlosberg D, Benifla M, Kaufer D, Friedman A.

Nat Rev Neurol. 2010 Jul;6(7):393-403. doi: 10.1038/nrneurol.2010.74. Epub 2010 Jun 15. Review.

13.

Age-dependent vascular changes induced by status epilepticus in rat forebrain: implications for epileptogenesis.

Marcon J, Gagliardi B, Balosso S, Maroso M, Noé F, Morin M, Lerner-Natoli M, Vezzani A, Ravizza T.

Neurobiol Dis. 2009 Apr;34(1):121-32.

PMID:
19320047
14.

Breaching the blood-brain barrier as a gate to psychiatric disorder.

Shalev H, Serlin Y, Friedman A.

Cardiovasc Psychiatry Neurol. 2009;2009:278531. doi: 10.1155/2009/278531. Epub 2009 Aug 27.

15.

Blood-brain barrier dysfunction, seizures and epilepsy.

van Vliet EA, Aronica E, Gorter JA.

Semin Cell Dev Biol. 2015 Feb;38:26-34. doi: 10.1016/j.semcdb.2014.10.003. Epub 2014 Nov 6. Review.

PMID:
25444846
16.

Cliniconeuropathologic correlations show astroglial albumin storage as a common factor in epileptogenic vascular lesions.

Raabe A, Schmitz AK, Pernhorst K, Grote A, von der Brelie C, Urbach H, Friedman A, Becker AJ, Elger CE, Niehusmann P.

Epilepsia. 2012 Mar;53(3):539-48. doi: 10.1111/j.1528-1167.2012.03405.x.

17.

Should losartan be administered following brain injury?

Friedman A, Bar-Klein G, Serlin Y, Parmet Y, Heinemann U, Kaufer D.

Expert Rev Neurother. 2014 Dec;14(12):1365-75. doi: 10.1586/14737175.2014.972945. Epub 2014 Oct 27. Review.

PMID:
25346269
18.

Focal astrocyte loss is followed by microvascular damage, with subsequent repair of the blood-brain barrier in the apparent absence of direct astrocytic contact.

Willis CL, Nolan CC, Reith SN, Lister T, Prior MJ, Guerin CJ, Mavroudis G, Ray DE.

Glia. 2004 Mar;45(4):325-37.

PMID:
14966864
19.

The angiotensin II type I receptor antagonist losartan retards amygdala kindling-induced epileptogenesis.

Nozaki T, Ura H, Takumi I, Kobayashi S, Maru E, Morita A.

Brain Res. 2018 May 19. pii: S0006-8993(18)30284-1. doi: 10.1016/j.brainres.2018.05.027. [Epub ahead of print]

PMID:
29787768
20.

[Inflammation, angiogenesis and epilepsy].

Lerner-Natoli M.

Biol Aujourdhui. 2011;205(1):33-41. doi: 10.1051/jbio/2011004. Epub 2011 Apr 19. Review. French.

PMID:
21501573

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