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Items: 1 to 20 of 126

1.

Systems-level interactions between insulin-EGF networks amplify mitogenic signaling.

Borisov N, Aksamitiene E, Kiyatkin A, Legewie S, Berkhout J, Maiwald T, Kaimachnikov NP, Timmer J, Hoek JB, Kholodenko BN.

Mol Syst Biol. 2009;5:256. doi: 10.1038/msb.2009.19. Epub 2009 Apr 7.

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A critical role for phosphoinositide 3-kinase upstream of Gab1 and SHP2 in the activation of ras and mitogen-activated protein kinases by epidermal growth factor.

Yart A, Laffargue M, Mayeux P, Chretien S, Peres C, Tonks N, Roche S, Payrastre B, Chap H, Raynal P.

J Biol Chem. 2001 Mar 23;276(12):8856-64. Epub 2000 Dec 27.

6.

Roles of Gab1 and SHP2 in paxillin tyrosine dephosphorylation and Src activation in response to epidermal growth factor.

Ren Y, Meng S, Mei L, Zhao ZJ, Jove R, Wu J.

J Biol Chem. 2004 Feb 27;279(9):8497-505. Epub 2003 Dec 8.

7.

The involvement of the docking protein Gab1 in mitogenic signalling induced by EGF and HGF in rat hepatocytes.

Aasrum M, Ødegård J, Sandnes D, Christoffersen T.

Biochim Biophys Acta. 2013 Dec;1833(12):3286-3294. doi: 10.1016/j.bbamcr.2013.10.004. Epub 2013 Oct 12.

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EGFR-activated Src family kinases maintain GAB1-SHP2 complexes distal from EGFR.

Furcht CM, Buonato JM, Lazzara MJ.

Sci Signal. 2015 May 12;8(376):ra46. doi: 10.1126/scisignal.2005697.

PMID:
25969544
14.

ERK negatively regulates the epidermal growth factor-mediated interaction of Gab1 and the phosphatidylinositol 3-kinase.

Yu CF, Liu ZX, Cantley LG.

J Biol Chem. 2002 May 31;277(22):19382-8. Epub 2002 Mar 14.

15.

Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF.

Saito T, Okada S, Ohshima K, Yamada E, Sato M, Uehara Y, Shimizu H, Pessin JE, Mori M.

Endocrinology. 2004 Sep;145(9):4232-43. Epub 2004 Jun 10.

PMID:
15192046
18.

Participation of both Gab1 and Gab2 in the activation of the ERK/MAPK pathway by epidermal growth factor.

Meng S, Chen Z, Munoz-Antonia T, Wu J.

Biochem J. 2005 Oct 1;391(Pt 1):143-51.

20.

Regulation of the mitogen-activated protein kinase signaling pathway by SHP2.

Cunnick JM, Meng S, Ren Y, Desponts C, Wang HG, Djeu JY, Wu J.

J Biol Chem. 2002 Mar 15;277(11):9498-504. Epub 2002 Jan 4.

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