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Items: 1 to 20 of 92

1.

JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.

Santaguida M, Schepers K, King B, Sabnis AJ, Forsberg EC, Attema JL, Braun BS, Passegué E.

Cancer Cell. 2009 Apr 7;15(4):341-52. doi: 10.1016/j.ccr.2009.02.016.

2.

JunB deficiency leads to a myeloproliferative disorder arising from hematopoietic stem cells.

Passegué E, Wagner EF, Weissman IL.

Cell. 2004 Oct 29;119(3):431-43.

3.

Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease.

Khandanpour C, Kosan C, Gaudreau MC, Dührsen U, Hébert J, Zeng H, Möröy T.

Stem Cells. 2011 Feb;29(2):376-85. doi: 10.1002/stem.575.

4.

Essential role of Jun family transcription factors in PU.1 knockdown-induced leukemic stem cells.

Steidl U, Rosenbauer F, Verhaak RG, Gu X, Ebralidze A, Otu HH, Klippel S, Steidl C, Bruns I, Costa DB, Wagner K, Aivado M, Kobbe G, Valk PJ, Passegué E, Libermann TA, Delwel R, Tenen DG.

Nat Genet. 2006 Nov;38(11):1269-77.

PMID:
17041602
5.

Pbx1 regulates self-renewal of long-term hematopoietic stem cells by maintaining their quiescence.

Ficara F, Murphy MJ, Lin M, Cleary ML.

Cell Stem Cell. 2008 May 8;2(5):484-96. doi: 10.1016/j.stem.2008.03.004.

6.

Divergent effects of supraphysiologic Notch signals on leukemia stem cells and hematopoietic stem cells.

Chiang MY, Shestova O, Xu L, Aster JC, Pear WS.

Blood. 2013 Feb 7;121(6):905-17. doi: 10.1182/blood-2012-03-416503.

7.

The Src homology 2 protein Shb promotes cell cycle progression in murine hematopoietic stem cells by regulation of focal adhesion kinase activity.

Gustafsson K, Heffner G, Wenzel PL, Curran M, Grawé J, McKinney-Freeman SL, Daley GQ, Welsh M.

Exp Cell Res. 2013 Jul 15;319(12):1852-64. doi: 10.1016/j.yexcr.2013.03.020.

PMID:
23528453
8.

Inflammation-mediated notch signaling skews fanconi anemia hematopoietic stem cell differentiation.

Du W, Amarachintha S, Sipple J, Schick J, Steinbrecher K, Pang Q.

J Immunol. 2013 Sep 1;191(5):2806-17. doi: 10.4049/jimmunol.1203474.

9.

The SKI proto-oncogene enhances the in vivo repopulation of hematopoietic stem cells and causes myeloproliferative disease.

Singbrant S, Wall M, Moody J, Karlsson G, Chalk AM, Liddicoat B, Russell MR, Walkley CR, Karlsson S.

Haematologica. 2014 Apr;99(4):647-55. doi: 10.3324/haematol.2013.093971.

10.

[Loss of junB expression causes a myeloproliferative syndrome resembling chronic myeloid leukemia].

Jochum W, Passegue E, Wagner EF.

Verh Dtsch Ges Pathol. 1999;83:216-7. German.

PMID:
10714213
11.

Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects.

Fleenor CJ, Rozhok AI, Zaberezhnyy V, Mathew D, Kim J, Tan AC, Bernstein ID, DeGregori J.

Stem Cells. 2015 Apr;33(4):1345-58. doi: 10.1002/stem.1936.

12.

Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic stem cell exhaustion and development of a myeloproliferative disorder in aging mice.

Singh KP, Bennett JA, Casado FL, Walrath JL, Welle SL, Gasiewicz TA.

Stem Cells Dev. 2014 Jan 15;23(2):95-106. doi: 10.1089/scd.2013.0346.

13.

TGF-beta signaling-deficient hematopoietic stem cells have normal self-renewal and regenerative ability in vivo despite increased proliferative capacity in vitro.

Larsson J, Blank U, Helgadottir H, Björnsson JM, Ehinger M, Goumans MJ, Fan X, Levéen P, Karlsson S.

Blood. 2003 Nov 1;102(9):3129-35.

14.

Selective activation of STAT5 unveils its role in stem cell self-renewal in normal and leukemic hematopoiesis.

Kato Y, Iwama A, Tadokoro Y, Shimoda K, Minoguchi M, Akira S, Tanaka M, Miyajima A, Kitamura T, Nakauchi H.

J Exp Med. 2005 Jul 4;202(1):169-79.

15.

Cell-intrinsic in vivo requirement for the E47-p21 pathway in long-term hematopoietic stem cells.

Santos PM, Ding Y, Borghesi L.

J Immunol. 2014 Jan 1;192(1):160-8. doi: 10.4049/jimmunol.1302502.

16.
17.

Murine hematopoietic stem cells and multipotent progenitors express truncated intracellular form of c-kit receptor.

Zayas J, Spassov DS, Nachtman RG, Jurecic R.

Stem Cells Dev. 2008 Apr;17(2):343-53. doi: 10.1089/scd.2007.0101.

18.

Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.

Butler JM, Nolan DJ, Vertes EL, Varnum-Finney B, Kobayashi H, Hooper AT, Seandel M, Shido K, White IA, Kobayashi M, Witte L, May C, Shawber C, Kimura Y, Kitajewski J, Rosenwaks Z, Bernstein ID, Rafii S.

Cell Stem Cell. 2010 Mar 5;6(3):251-64. doi: 10.1016/j.stem.2010.02.001.

19.

E47 regulates hematopoietic stem cell proliferation and energetics but not myeloid lineage restriction.

Yang Q, Esplin B, Borghesi L.

Blood. 2011 Mar 31;117(13):3529-38. doi: 10.1182/blood-2010-07-297689.

20.

Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.

Naramura M, Nandwani N, Gu H, Band V, Band H.

Proc Natl Acad Sci U S A. 2010 Sep 14;107(37):16274-9. doi: 10.1073/pnas.1007575107.

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