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Items: 1 to 20 of 103

1.

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis.

Adorno M, Cordenonsi M, Montagner M, Dupont S, Wong C, Hann B, Solari A, Bobisse S, Rondina MB, Guzzardo V, Parenti AR, Rosato A, Bicciato S, Balmain A, Piccolo S.

Cell. 2009 Apr 3;137(1):87-98. doi: 10.1016/j.cell.2009.01.039.

2.

beta-tting on p63 as a metastatic suppressor.

Clohessy JG, Pandolfi PP.

Cell. 2009 Apr 3;137(1):28-30. doi: 10.1016/j.cell.2009.03.028.

3.

Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair.

Marine JC, Berx G.

Breast Cancer Res. 2009;11(4):304. doi: 10.1186/bcr2337. Epub 2009 Jul 27.

4.

Pro-metastasis function of TGFbeta mediated by the Smad pathway.

Kang Y.

J Cell Biochem. 2006 Aug 15;98(6):1380-90. Review.

PMID:
16598746
5.

Loss of p63 leads to increased cell migration and up-regulation of genes involved in invasion and metastasis.

Barbieri CE, Tang LJ, Brown KA, Pietenpol JA.

Cancer Res. 2006 Aug 1;66(15):7589-97.

6.

B-MYB is required for recovery from the DNA damage-induced G2 checkpoint in p53 mutant cells.

Mannefeld M, Klassen E, Gaubatz S.

Cancer Res. 2009 May 1;69(9):4073-80. doi: 10.1158/0008-5472.CAN-08-4156. Epub 2009 Apr 21.

7.

p53 and TGF-beta in development: prelude to tumor suppression?

Whitman M, McKeon F.

Cell. 2003 May 2;113(3):275-6.

8.

The p53-homologue p63 may promote thyroid cancer progression.

Malaguarnera R, Mandarino A, Mazzon E, Vella V, Gangemi P, Vancheri C, Vigneri P, Aloisi A, Vigneri R, Frasca F.

Endocr Relat Cancer. 2005 Dec;12(4):953-71.

9.
10.

Does TP53 mutation promote ovarian cancer metastasis to omentum by regulating lipid metabolism?

Hu J, Liu Z, Wang X.

Med Hypotheses. 2013 Oct;81(4):515-20. doi: 10.1016/j.mehy.2013.06.009. Epub 2013 Jul 20.

PMID:
23880140
11.

p53 and ΔNp63α Coregulate the Transcriptional and Cellular Response to TGFβ and BMP Signals.

Balboni AL, Cherukuri P, Ung M, DeCastro AJ, Cheng C, DiRenzo J.

Mol Cancer Res. 2015 Apr;13(4):732-42. doi: 10.1158/1541-7786.MCR-14-0152-T. Epub 2015 Feb 19.

12.

Inhibiting breast cancer progression by exploiting TGFbeta signaling.

Baxley SE, Serra R.

Curr Drug Targets. 2010 Sep;11(9):1089-102. Review.

PMID:
20545612
13.

p63: oncogene or tumor suppressor?

Mills AA.

Curr Opin Genet Dev. 2006 Feb;16(1):38-44. Epub 2005 Dec 15. Review.

PMID:
16359856
14.

Expression of Ki-67, p53 and p63 proteins in keratocyst odontogenic tumours: an immunohistochemical study.

Gurgel CA, Ramos EA, Azevedo RA, Sarmento VA, da Silva Carvalho AM, dos Santos JN.

J Mol Histol. 2008 Jun;39(3):311-6. doi: 10.1007/s10735-008-9167-0. Epub 2008 Feb 7.

PMID:
18256893
15.

p63 consensus DNA-binding site: identification, analysis and application into a p63MH algorithm.

Perez CA, Ott J, Mays DJ, Pietenpol JA.

Oncogene. 2007 Nov 15;26(52):7363-70. Epub 2007 Jun 11.

PMID:
17563751
16.

P53, p63 and Ki-67 assessment in HPV-induced cervical neoplasia.

Vasilescu F, Ceauşu M, Tănase C, Stănculescu R, Vlădescu T, Ceauşu Z.

Rom J Morphol Embryol. 2009;50(3):357-61.

17.

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.

Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, Ambs S, Sharma S, Wakefield LM, Meltzer PS, Lal A.

Oncogene. 2015 Feb 26;34(9):1094-104. doi: 10.1038/onc.2014.46. Epub 2014 Mar 24.

18.

Mediator MED15 modulates transforming growth factor beta (TGFβ)/Smad signaling and breast cancer cell metastasis.

Zhao M, Yang X, Fu Y, Wang H, Ning Y, Yan J, Chen YG, Wang G.

J Mol Cell Biol. 2013 Feb;5(1):57-60. doi: 10.1093/jmcb/mjs054. Epub 2012 Sep 26. No abstract available.

PMID:
23014762
19.

Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes.

Guo J, Canaff L, Rajadurai CV, Fils-Aimé N, Tian J, Dai M, Korah J, Villatoro M, Park M, Ali S, Lebrun JJ.

Breast Cancer Res. 2014 Dec 13;16(6):476. doi: 10.1186/s13058-014-0476-9.

20.

Tumor suppressor p53 restricts Ras stimulation of RhoA and cancer cell motility.

Xia M, Land H.

Nat Struct Mol Biol. 2007 Mar;14(3):215-23. Epub 2007 Feb 18.

PMID:
17310253

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