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Items: 1 to 20 of 54

1.

Winter temperature and UV are tightly linked to genetic changes in the p53 tumor suppressor pathway in Eastern Asia.

Shi H, Tan SJ, Zhong H, Hu W, Levine A, Xiao CJ, Peng Y, Qi XB, Shou WH, Ma RL, Li Y, Su B, Lu X.

Am J Hum Genet. 2009 Apr;84(4):534-41. doi: 10.1016/j.ajhg.2009.03.009. Epub 2009 Apr 2.

2.

Risk of MDM2 SNP309 alone or in combination with the p53 codon 72 polymorphism in acute myeloid leukemia.

Xiong X, Wang M, Wang L, Liu J, Zhao X, Tian Z, Wang J.

Leuk Res. 2009 Nov;33(11):1454-8. doi: 10.1016/j.leukres.2009.04.007. Epub 2009 May 6.

PMID:
19423162
3.

Haplotype structure and selection of the MDM2 oncogene in humans.

Atwal GS, Bond GL, Metsuyanim S, Papa M, Friedman E, Distelman-Menachem T, Ben Asher E, Lancet D, Ross DA, Sninsky J, White TJ, Levine AJ, Yarden R.

Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4524-9. Epub 2007 Mar 5.

4.

Mdm2 Snp309 G allele displays high frequency and inverse correlation with somatic P53 mutations in hepatocellular carcinoma.

Acun T, Terzioğlu-Kara E, Konu O, Ozturk M, Yakicier MC.

Mutat Res. 2010 Feb 3;684(1-2):106-8. doi: 10.1016/j.mrfmmm.2009.11.008. Epub 2009 Nov 30.

PMID:
19954744
5.

Natural selection and functional genetic variation in the p53 pathway.

Sucheston L, Witonsky DB, Hastings D, Yildiz O, Clark VJ, Di Rienzo A, Onel K.

Hum Mol Genet. 2011 Apr 15;20(8):1502-8. doi: 10.1093/hmg/ddr028. Epub 2011 Jan 25.

7.

Association of p53 codon 72 polymorphism and MDM2 SNP309 with clinical outcome of advanced nonsmall cell lung cancer.

Han JY, Lee GK, Jang DH, Lee SY, Lee JS.

Cancer. 2008 Aug 15;113(4):799-807. doi: 10.1002/cncr.23668.

8.

Lack of association of the TP53 Arg72Pro SNP and the MDM2 SNP309 with systemic lupus erythematosus in Caucasian, African American, and Asian children and adults.

Onel KB, Huo D, Hastings D, Fryer-Biggs J, Crow MK, Onel K.

Lupus. 2009 Jan;18(1):61-6. doi: 10.1177/0961203308094558.

9.

Polymorphisms of p53 codon 72 and MDM2 promoter 309 and the risk of endometrial cancer.

Nunobiki O, Ueda M, Yamamoto M, Toji E, Sato N, Izuma S, Okamoto Y, Torii K, Noda S.

Hum Cell. 2009 Nov;22(4):101-6. doi: 10.1111/j.1749-0774.2009.00075.x.

PMID:
19874399
10.

p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome.

Sotamaa K, Liyanarachchi S, Mecklin JP, Järvinen H, Aaltonen LA, Peltomäki P, de la Chapelle A.

Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6840-4.

11.

Association of breast cancer outcome with status of p53 and MDM2 SNP309.

Boersma BJ, Howe TM, Goodman JE, Yfantis HG, Lee DH, Chanock SJ, Ambs S.

J Natl Cancer Inst. 2006 Jul 5;98(13):911-9.

PMID:
16818855
12.

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients.

Schmidt MK, Tommiska J, Broeks A, van Leeuwen FE, Van't Veer LJ, Pharoah PD, Easton DF, Shah M, Humphreys M, Dörk T, Reincke SA, Fagerholm R, Blomqvist C, Nevanlinna H.

Breast Cancer Res. 2009;11(6):R89. doi: 10.1186/bcr2460. Epub 2009 Dec 18.

13.

A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells.

Hu W, Feng Z, Ma L, Wagner J, Rice JJ, Stolovitzky G, Levine AJ.

Cancer Res. 2007 Mar 15;67(6):2757-65.

14.

MDM2 SNP 309 and p53 codon 72 polymorphisms are associated with the outcome of oral carcinoma patients receiving postoperative irradiation.

Tu HF, Chen HW, Kao SY, Lin SC, Liu CJ, Chang KW.

Radiother Oncol. 2008 May;87(2):243-52. doi: 10.1016/j.radonc.2008.03.018. Epub 2008 Apr 16.

PMID:
18423915
15.

The impact of natural selection on an ABCC11 SNP determining earwax type.

Ohashi J, Naka I, Tsuchiya N.

Mol Biol Evol. 2011 Jan;28(1):849-57. doi: 10.1093/molbev/msq264. Epub 2010 Oct 11.

PMID:
20937735
16.

The significance of MDM2 SNP309 and p53 Arg72Pro in young women with breast cancer.

Lång A, Palmebäck Wegman P, Wingren S.

Oncol Rep. 2009 Sep;22(3):575-9.

PMID:
19639206
17.

[Genetic polymorphism in MDM2 is associated with susceptibility to colorectal cancer in a Chinese population].

Liu JN, Zhang XM, Guo YL, Sun T, Lin DX, Wen T.

Zhonghua Zhong Liu Za Zhi. 2008 May;30(5):335-8. Chinese.

PMID:
18953830
18.

MDM2 SNP309 G allele increases risk but the T allele is associated with earlier onset age of sporadic breast cancers in the Chinese population.

Lum SS, Chua HW, Li H, Li WF, Rao N, Wei J, Shao Z, Sabapathy K.

Carcinogenesis. 2008 Apr;29(4):754-61. doi: 10.1093/carcin/bgn024. Epub 2008 Feb 14.

PMID:
18281248
19.

p53 polymorphisms and haplotypes show distinct differences between major ethnic groups.

Själander A, Birgander R, Saha N, Beckman L, Beckman G.

Hum Hered. 1996 Jan-Feb;46(1):41-8.

PMID:
8825462
20.

Effects of MDM2, MDM4 and TP53 codon 72 polymorphisms on cancer risk in a cohort study of carriers of TP53 germline mutations.

Fang S, Krahe R, Lozano G, Han Y, Chen W, Post SM, Zhang B, Wilson CD, Bachinski LL, Strong LC, Amos CI.

PLoS One. 2010 May 26;5(5):e10813. doi: 10.1371/journal.pone.0010813.

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