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Items: 1 to 20 of 392

1.

Atg5 regulates phenethyl isothiocyanate-induced autophagic and apoptotic cell death in human prostate cancer cells.

Bommareddy A, Hahm ER, Xiao D, Powolny AA, Fisher AL, Jiang Y, Singh SV.

Cancer Res. 2009 Apr 15;69(8):3704-12. doi: 10.1158/0008-5472.CAN-08-4344. Epub 2009 Mar 31.

2.

Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells.

Xiao D, Powolny AA, Moura MB, Kelley EE, Bommareddy A, Kim SH, Hahm ER, Normolle D, Van Houten B, Singh SV.

J Biol Chem. 2010 Aug 20;285(34):26558-69. doi: 10.1074/jbc.M109.063255. Epub 2010 Jun 22.

4.

Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells.

Herman-Antosiewicz A, Johnson DE, Singh SV.

Cancer Res. 2006 Jun 1;66(11):5828-35.

5.

Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells.

Hu H, Chai Y, Wang L, Zhang J, Lee HJ, Kim SH, Lü J.

Mol Cancer Ther. 2009 Oct;8(10):2833-43. doi: 10.1158/1535-7163.MCT-09-0288.

6.

Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling.

Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, Huang C, Wei Y.

Autophagy. 2011 Sep;7(9):966-78. Epub 2011 Sep 1.

PMID:
21610320
8.
9.

Chemopreventative potential of the cruciferous vegetable constituent phenethyl isothiocyanate in a mouse model of prostate cancer.

Powolny AA, Bommareddy A, Hahm ER, Normolle DP, Beumer JH, Nelson JB, Singh SV.

J Natl Cancer Inst. 2011 Apr 6;103(7):571-84. doi: 10.1093/jnci/djr029. Epub 2011 Feb 17.

10.

p66Shc is indispensable for phenethyl isothiocyanate-induced apoptosis in human prostate cancer cells.

Xiao D, Singh SV.

Cancer Res. 2010 Apr 15;70(8):3150-8. doi: 10.1158/0008-5472.CAN-09-4451. Epub 2010 Mar 30.

11.

Mammalian target of rapamycin regulates isoliquiritigenin-induced autophagic and apoptotic cell death in adenoid cystic carcinoma cells.

Chen G, Hu X, Zhang W, Xu N, Wang FQ, Jia J, Zhang WF, Sun ZJ, Zhao YF.

Apoptosis. 2012 Jan;17(1):90-101. doi: 10.1007/s10495-011-0658-1.

PMID:
21956714
12.

Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.

Xiao D, Bommareddy A, Kim SH, Sehrawat A, Hahm ER, Singh SV.

PLoS One. 2012;7(3):e32597. doi: 10.1371/journal.pone.0032597. Epub 2012 Mar 22.

13.

Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration.

Kim SH, Sehrawat A, Sakao K, Hahm ER, Singh SV.

PLoS One. 2011;6(10):e26615. doi: 10.1371/journal.pone.0026615. Epub 2011 Oct 24.

14.

Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.

Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.

Carcinogenesis. 2006 Nov;27(11):2223-34. Epub 2006 Jun 13.

PMID:
16774948
15.

Bim contributes to phenethyl isothiocyanate-induced apoptosis in breast cancer cells.

Hahm ER, Singh SV.

Mol Carcinog. 2012 Jun;51(6):465-74. doi: 10.1002/mc.20811. Epub 2011 Jul 7.

16.

Benzyl isothiocyanate induces protective autophagy in human prostate cancer cells via inhibition of mTOR signaling.

Lin JF, Tsai TF, Liao PC, Lin YH, Lin YC, Chen HE, Chou KY, Hwang TI.

Carcinogenesis. 2013 Feb;34(2):406-14. doi: 10.1093/carcin/bgs359. Epub 2012 Nov 21.

PMID:
23172666
17.

Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo.

Sakao K, Desineni S, Hahm ER, Singh SV.

Prostate. 2012 Jul 1;72(10):1104-16. doi: 10.1002/pros.22457. Epub 2011 Dec 7.

18.

Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo.

Xiao D, Singh SV.

Pharm Res. 2010 Apr;27(4):722-31. doi: 10.1007/s11095-010-0079-9. Epub 2010 Feb 25.

19.

Inhibition of EGFR signaling in human prostate cancer PC-3 cells by combination treatment with beta-phenylethyl isothiocyanate and curcumin.

Kim JH, Xu C, Keum YS, Reddy B, Conney A, Kong AN.

Carcinogenesis. 2006 Mar;27(3):475-82. Epub 2005 Nov 19.

PMID:
16299382
20.

Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate.

Wang LG, Liu XM, Chiao JW.

Carcinogenesis. 2006 Oct;27(10):2124-32. Epub 2006 May 16. Erratum in: Carcinogenesis. 2007 Mar;28(3):767.

PMID:
16704988

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