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Items: 1 to 20 of 116

1.

Blockade of Dickkopf (DKK)-1 induces fusion of sacroiliac joints.

Uderhardt S, Diarra D, Katzenbeisser J, David JP, Zwerina J, Richards W, Kronke G, Schett G.

Ann Rheum Dis. 2010 Mar;69(3):592-7. doi: 10.1136/ard.2008.102046. Epub 2009 Mar 19.

PMID:
19304568
2.

Interleukin 6 is not a crucial regulator in an animal model of tumour necrosis factor-mediated bilateral sacroiliitis.

Hayer S, Niederreiter B, Nagelreiter I, Smolen J, Redlich K.

Ann Rheum Dis. 2010 Jul;69(7):1403-6. doi: 10.1136/ard.2010.129148. Epub 2010 May 24.

PMID:
20498200
3.

Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction.

Zwerina J, Hayer S, Tohidast-Akrad M, Bergmeister H, Redlich K, Feige U, Dunstan C, Kollias G, Steiner G, Smolen J, Schett G.

Arthritis Rheum. 2004 Jan;50(1):277-90.

4.

R-spondin 1 protects against inflammatory bone damage during murine arthritis by modulating the Wnt pathway.

Krönke G, Uderhardt S, Kim KA, Stock M, Scholtysek C, Zaiss MM, Surmann-Schmitt C, Luther J, Katzenbeisser J, David JP, Abdollahi-Roodsaz S, Tran K, Bright JM, Binnerts ME, Akhmetshina A, Böhm C, Distler JH, Joosten LA, Schett G, Abo A.

Arthritis Rheum. 2010 Aug;62(8):2303-12. doi: 10.1002/art.27496.

5.
6.

Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints.

Polzer K, Baeten D, Soleiman A, Distler J, Gerlag DM, Tak PP, Schett G, Zwerina J.

Ann Rheum Dis. 2008 Nov;67(11):1610-6. doi: 10.1136/ard.2007.083394. Epub 2008 Jan 3.

PMID:
18174217
7.

Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction.

Zwerina J, Hayer S, Redlich K, Bobacz K, Kollias G, Smolen JS, Schett G.

Arthritis Rheum. 2006 Feb;54(2):463-72.

8.

Evidence that Dkk-1 is dysfunctional in ankylosing spondylitis.

Daoussis D, Liossis SN, Solomou EE, Tsanaktsi A, Bounia K, Karampetsou M, Yiannopoulos G, Andonopoulos AP.

Arthritis Rheum. 2010 Jan;62(1):150-8. doi: 10.1002/art.27231.

10.

Dickkopf-1 is a master regulator of joint remodeling.

Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G.

Nat Med. 2007 Feb;13(2):156-63. Epub 2007 Jan 21.

PMID:
17237793
11.

Effect of tumour necrosis factor-α inhibitor on serum level of dickkopf-1 protein and bone morphogenetic protein-7 in ankylosing spondylitis patients with high disease activity.

Korkosz M, Gąsowski J, Leszczyński P, Pawlak-Buś K, Jeka S, Siedlar M, Grodzicki T.

Scand J Rheumatol. 2014;43(1):43-8. doi: 10.3109/03009742.2013.805241. Epub 2013 Sep 8.

PMID:
24447112
12.

Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target.

Boettger MK, Hensellek S, Richter F, Gajda M, Stöckigt R, von Banchet GS, Bräuer R, Schaible HG.

Arthritis Rheum. 2008 Aug;58(8):2368-78. doi: 10.1002/art.23608.

14.

Treatment with anti-gamma-glutamyl transpeptidase antibody attenuates osteolysis in collagen-induced arthritis mice.

Ishizuka Y, Moriwaki S, Kawahara-Hanaoka M, Uemura Y, Serizawa I, Miyauchi M, Shibata S, Kanaya T, Takata T, Taniguchi N, Niida S.

J Bone Miner Res. 2007 Dec;22(12):1933-42.

15.

Aberrant chondrocyte hypertrophy and activation of β-catenin signaling precede joint ankylosis in ank/ank mice.

Las Heras F, Pritzker KP, So A, Tsui HW, Chiu B, Inman RD, Tsui FW.

J Rheumatol. 2012 Mar;39(3):583-93. doi: 10.3899/jrheum.110971. Epub 2012 Feb 1.

PMID:
22298904
16.

Tumor necrosis factor prevents alendronate-induced osteoclast apoptosis in vivo by stimulating Bcl-xL expression through Ets-2.

Zhang Q, Badell IR, Schwarz EM, Boulukos KE, Yao Z, Boyce BF, Xing L.

Arthritis Rheum. 2005 Sep;52(9):2708-18.

17.

Remission of collagen-induced arthritis is associated with high levels of transforming growth factor-beta expression in the joint.

Marinova-Mutafchieva L, Gabay C, Funa K, Williams RO.

Clin Exp Immunol. 2006 Nov;146(2):287-93.

18.

Computed tomography guided intra-articular injection of etanercept in the sacroiliac joint is an effective mode of treatment of ankylosing spondylitis.

Cui Y, Xiao Z, Shuxia W, Zhenjun Z, Hengguo Z, Liangyi F, Weicheng G, Li L, Guangfeng Z, Yunzhen S, Guangfu D.

Scand J Rheumatol. 2010 May;39(3):229-32. doi: 10.3109/03009740903313613.

PMID:
20109079
19.

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses.

Fujimoto M, Serada S, Mihara M, Uchiyama Y, Yoshida H, Koike N, Ohsugi Y, Nishikawa T, Ripley B, Kimura A, Kishimoto T, Naka T.

Arthritis Rheum. 2008 Dec;58(12):3710-9. doi: 10.1002/art.24126.

20.

The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal stem cell niche.

Aicher A, Kollet O, Heeschen C, Liebner S, Urbich C, Ihling C, Orlandi A, Lapidot T, Zeiher AM, Dimmeler S.

Circ Res. 2008 Oct 10;103(8):796-803. doi: 10.1161/CIRCRESAHA.107.172718. Epub 2008 Sep 5.

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