Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 104

1.

Airway and lung pathology due to mucosal surface dehydration in {beta}-epithelial Na+ channel-overexpressing mice: role of TNF-{alpha} and IL-4R{alpha} signaling, influence of neonatal development, and limited efficacy of glucocorticoid treatment.

Livraghi A, Grubb BR, Hudson EJ, Wilkinson KJ, Sheehan JK, Mall MA, O'Neal WK, Boucher RC, Randell SH.

J Immunol. 2009 Apr 1;182(7):4357-67. doi: 10.4049/jimmunol.0802557.

2.

Development of chronic bronchitis and emphysema in beta-epithelial Na+ channel-overexpressing mice.

Mall MA, Harkema JR, Trojanek JB, Treis D, Livraghi A, Schubert S, Zhou Z, Kreda SM, Tilley SL, Hudson EJ, O'Neal WK, Boucher RC.

Am J Respir Crit Care Med. 2008 Apr 1;177(7):730-42. Epub 2007 Dec 13.

3.

Mucus clearance, MyD88-dependent and MyD88-independent immunity modulate lung susceptibility to spontaneous bacterial infection and inflammation.

Livraghi-Butrico A, Kelly EJ, Klem ER, Dang H, Wolfgang MC, Boucher RC, Randell SH, O'Neal WK.

Mucosal Immunol. 2012 Jul;5(4):397-408. doi: 10.1038/mi.2012.17. Epub 2012 Mar 14.

4.

Genetically determined heterogeneity of lung disease in a mouse model of airway mucus obstruction.

Livraghi-Butrico A, Grubb BR, Kelly EJ, Wilkinson KJ, Yang H, Geiser M, Randell SH, Boucher RC, O'Neal WK.

Physiol Genomics. 2012 Apr 15;44(8):470-84. doi: 10.1152/physiolgenomics.00185.2011. Epub 2012 Mar 6.

5.

Hypoxic epithelial necrosis triggers neutrophilic inflammation via IL-1 receptor signaling in cystic fibrosis lung disease.

Fritzsching B, Zhou-Suckow Z, Trojanek JB, Schubert SC, Schatterny J, Hirtz S, Agrawal R, Muley T, Kahn N, Sticht C, Gunkel N, Welte T, Randell SH, Länger F, Schnabel P, Herth FJ, Mall MA.

Am J Respir Crit Care Med. 2015 Apr 15;191(8):902-13. doi: 10.1164/rccm.201409-1610OC.

6.

Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration.

Saini Y, Dang H, Livraghi-Butrico A, Kelly EJ, Jones LC, O'Neal WK, Boucher RC.

BMC Genomics. 2014 Sep 10;15:726. doi: 10.1186/1471-2164-15-726.

7.

Impaired mucus clearance exacerbates allergen-induced type 2 airway inflammation in juvenile mice.

Fritzsching B, Hagner M, Dai L, Christochowitz S, Agrawal R, van Bodegom C, Schmidt S, Schatterny J, Hirtz S, Brown R, Goritzka M, Duerr J, Zhou-Suckow Z, Mall MA.

J Allergy Clin Immunol. 2017 Jul;140(1):190-203.e5. doi: 10.1016/j.jaci.2016.09.045. Epub 2016 Nov 16.

PMID:
27865862
8.

Neonatal Pulmonary Macrophage Depletion Coupled to Defective Mucus Clearance Increases Susceptibility to Pneumonia and Alters Pulmonary Immune Responses.

Saini Y, Wilkinson KJ, Terrell KA, Burns KA, Livraghi-Butrico A, Doerschuk CM, O'Neal WK, Boucher RC.

Am J Respir Cell Mol Biol. 2016 Feb;54(2):210-21. doi: 10.1165/rcmb.2014-0111OC.

9.

Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways.

Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR.

Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L469-80. doi: 10.1152/ajplung.00150.2012. Epub 2013 Feb 1.

10.

Lack of neutrophil elastase reduces inflammation, mucus hypersecretion, and emphysema, but not mucus obstruction, in mice with cystic fibrosis-like lung disease.

Gehrig S, Duerr J, Weitnauer M, Wagner CJ, Graeber SY, Schatterny J, Hirtz S, Belaaouaj A, Dalpke AH, Schultz C, Mall MA.

Am J Respir Crit Care Med. 2014 May 1;189(9):1082-92. doi: 10.1164/rccm.201311-1932OC.

PMID:
24678594
11.

CFTR regulates early pathogenesis of chronic obstructive lung disease in βENaC-overexpressing mice.

Johannesson B, Hirtz S, Schatterny J, Schultz C, Mall MA.

PLoS One. 2012;7(8):e44059. doi: 10.1371/journal.pone.0044059. Epub 2012 Aug 24.

12.

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

Livraghi-Butrico A, Grubb BR, Wilkinson KJ, Volmer AS, Burns KA, Evans CM, O'Neal WK, Boucher RC.

Mucosal Immunol. 2017 Mar;10(2):395-407. doi: 10.1038/mi.2016.63. Epub 2016 Jul 20.

13.

Hypertonic saline is effective in the prevention and treatment of mucus obstruction, but not airway inflammation, in mice with chronic obstructive lung disease.

Graeber SY, Zhou-Suckow Z, Schatterny J, Hirtz S, Boucher RC, Mall MA.

Am J Respir Cell Mol Biol. 2013 Sep;49(3):410-7. doi: 10.1165/rcmb.2013-0050OC. Erratum in: Am J Respir Cell Mol Biol. 2014 Apr;50(4):838.

14.

Airway mucus obstruction triggers macrophage activation and matrix metalloproteinase 12-dependent emphysema.

Trojanek JB, Cobos-Correa A, Diemer S, Kormann M, Schubert SC, Zhou-Suckow Z, Agrawal R, Duerr J, Wagner CJ, Schatterny J, Hirtz S, Sommerburg O, Hartl D, Schultz C, Mall MA.

Am J Respir Cell Mol Biol. 2014 Nov;51(5):709-20. doi: 10.1165/rcmb.2013-0407OC.

PMID:
24828142
15.

Effect of LysM+ macrophage depletion on lung pathology in mice with chronic bronchitis.

Saini Y, Lewis BW, Yu D, Dang H, Livraghi-Butrico A, Del Piero F, O'Neal WK, Boucher RC.

Physiol Rep. 2018 Apr;6(8):e13677. doi: 10.14814/phy2.13677.

16.

Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice.

Karras JG, Crosby JR, Guha M, Tung D, Miller DA, Gaarde WA, Geary RS, Monia BP, Gregory SA.

Am J Respir Cell Mol Biol. 2007 Mar;36(3):276-85. Epub 2006 Sep 21.

PMID:
16990616
17.

Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease.

Lewis BW, Sultana R, Sharma R, Noël A, Langohr I, Patial S, Penn AL, Saini Y.

J Immunol. 2017 Aug 1;199(3):1170-1183. doi: 10.4049/jimmunol.1700144. Epub 2017 Jun 30.

PMID:
28667160
18.

Role of Spdef in the Regulation of Muc5b Expression in the Airways of Naïve and Muco-obstructed Mice.

Chen G, Volmer AS, Wilkinson KJ, Deng Y, Jones LC, Yu D, Bustamante-Marin XM, Burns KA, Grubb BR, O'Neal WK, Livraghi-Butrico A, Boucher RC.

Am J Respir Cell Mol Biol. 2018 Mar 26. doi: 10.1165/rcmb.2017-0127OC. [Epub ahead of print]

PMID:
29579396
19.

Adoptive transfer of IL-4Rα+ macrophages is sufficient to enhance eosinophilic inflammation in a mouse model of allergic lung inflammation.

Ford AQ, Dasgupta P, Mikhailenko I, Smith EM, Noben-Trauth N, Keegan AD.

BMC Immunol. 2012 Jan 31;13:6. doi: 10.1186/1471-2172-13-6.

20.

Supplemental Content

Support Center