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Items: 1 to 20 of 478


Mucosal vaccination with a multicomponent adenovirus-vectored vaccine protects against Streptococcus pneumoniae infection in the lung.

Arévalo MT, Xu Q, Paton JC, Hollingshead SK, Pichichero ME, Briles DE, Girgis N, Zeng M.

FEMS Immunol Med Microbiol. 2009 Apr;55(3):346-51. doi: 10.1111/j.1574-695X.2008.00518.x.


Protection against Pneumococcal colonization and fatal pneumonia by a trivalent conjugate of a fusion protein with the cell wall polysaccharide.

Lu YJ, Forte S, Thompson CM, Anderson PW, Malley R.

Infect Immun. 2009 May;77(5):2076-83. doi: 10.1128/IAI.01554-08. Epub 2009 Mar 2.


Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A.

Oliveira ML, Arêas AP, Campos IB, Monedero V, Perez-Martínez G, Miyaji EN, Leite LC, Aires KA, Lee Ho P.

Microbes Infect. 2006 Apr;8(4):1016-24.


PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae.

Miyaji EN, Dias WO, Gamberini M, Gebara VC, Schenkman RP, Wild J, Riedl P, Reimann J, Schirmbeck R, Leite LC.

Vaccine. 2001 Dec 12;20(5-6):805-12.


Immunizations with pneumococcal surface protein A and pneumolysin are protective against pneumonia in a murine model of pulmonary infection with Streptococcus pneumoniae.

Briles DE, Hollingshead SK, Paton JC, Ades EW, Novak L, van Ginkel FW, Benjamin WH Jr.

J Infect Dis. 2003 Aug 1;188(3):339-48. Epub 2003 Jul 14.


Mucosal delivery of a pneumococcal vaccine using Lactococcus lactis affords protection against respiratory infection.

Hanniffy SB, Carter AT, Hitchin E, Wells JM.

J Infect Dis. 2007 Jan 15;195(2):185-93. Epub 2006 Dec 4.


PspA family fusion proteins delivered by attenuated Salmonella enterica serovar Typhimurium extend and enhance protection against Streptococcus pneumoniae.

Xin W, Li Y, Mo H, Roland KL, Curtiss R 3rd.

Infect Immun. 2009 Oct;77(10):4518-28. doi: 10.1128/IAI.00486-09. Epub 2009 Aug 17.


Protective Immune Responses Elicited by Fusion Protein Containing PsaA and PspA Fragments.

Lu J, Sun T, Wang D, Dong Y, Xu M, Hou H, Kong FT, Liang C, Gu T, Chen P, Sun S, Lv X, Jiang C, Kong W, Wu Y.

Immunol Invest. 2015;44(5):482-96. doi: 10.3109/08820139.2015.1037956.


Characterization of the antibody response elicited by immunization with pneumococcal surface protein A (PspA) as recombinant protein or DNA vaccine and analysis of protection against an intranasal lethal challenge with Streptococcus pneumoniae.

Vadesilho CF, Ferreira DM, Moreno AT, Chavez-Olortegui C, Machado de Avila RA, Oliveira ML, Ho PL, Miyaji EN.

Microb Pathog. 2012 Nov-Dec;53(5-6):243-9. doi: 10.1016/j.micpath.2012.08.007. Epub 2012 Sep 7.


A protein-based pneumococcal vaccine protects rhesus macaques from pneumonia after experimental infection with Streptococcus pneumoniae.

Denoël P, Philipp MT, Doyle L, Martin D, Carletti G, Poolman JT.

Vaccine. 2011 Jul 26;29(33):5495-501. doi: 10.1016/j.vaccine.2011.05.051. Epub 2011 May 30.


Immune responses to recombinant pneumococcal PsaA antigen delivered by a live attenuated Salmonella vaccine.

Wang S, Li Y, Shi H, Scarpellini G, Torres-Escobar A, Roland KL, Curtiss R 3rd.

Infect Immun. 2010 Jul;78(7):3258-71. doi: 10.1128/IAI.00176-10. Epub 2010 May 17.


Novel mucosal vaccines generated by genetic conjugation of heterologous proteins to pneumolysin (PLY) from Streptococcus pneumoniae.

Douce G, Ross K, Cowan G, Ma J, Mitchell TJ.

Vaccine. 2010 Apr 19;28(18):3231-7. doi: 10.1016/j.vaccine.2010.02.014. Epub 2010 Feb 24.


Intranasal vaccination with chitosan-DNA nanoparticles expressing pneumococcal surface antigen a protects mice against nasopharyngeal colonization by Streptococcus pneumoniae.

Xu J, Dai W, Wang Z, Chen B, Li Z, Fan X.

Clin Vaccine Immunol. 2011 Jan;18(1):75-81. doi: 10.1128/CVI.00263-10. Epub 2010 Nov 3.


The potential for using protein vaccines to protect against otitis media caused by Streptococcus pneumoniae.

Briles DE, Hollingshead SK, Nabors GS, Paton JC, Brooks-Walter A.

Vaccine. 2000 Dec 8;19 Suppl 1:S87-95. Review.


Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge.

Campos IB, Darrieux M, Ferreira DM, Miyaji EN, Silva DA, Arêas AP, Aires KA, Leite LC, Ho PL, Oliveira ML.

Microbes Infect. 2008 Apr;10(5):481-8. doi: 10.1016/j.micinf.2008.01.007.


Enhanced immunogenicity of pneumococcal surface adhesin A by genetic fusion to cytokines and evaluation of protective immunity in mice.

Gor DO, Ding X, Li Q, Schreiber JR, Dubinsky M, Greenspan NS.

Infect Immun. 2002 Oct;70(10):5589-95.


Intranasal immunization with recombinant PspA fused with a flagellin enhances cross-protective immunity against Streptococcus pneumoniae infection in mice.

Nguyen CT, Kim SY, Kim MS, Lee SE, Rhee JH.

Vaccine. 2011 Aug 5;29(34):5731-9. doi: 10.1016/j.vaccine.2011.05.095. Epub 2011 Jun 13.


Immunization with a combination of three pneumococcal proteins confers additive and broad protection against Streptococcus pneumoniae Infections in Mice.

Wu K, Zhang X, Shi J, Li N, Li D, Luo M, Cao J, Yin N, Wang H, Xu W, He Y, Yin Y.

Infect Immun. 2010 Mar;78(3):1276-83. doi: 10.1128/IAI.00473-09. Epub 2009 Dec 28.


Mucosal immunization with an unadjuvanted vaccine that targets Streptococcus pneumoniae PspA to human Fcγ receptor type I protects against pneumococcal infection through complement- and lactoferrin-mediated bactericidal activity.

Bitsaktsis C, Iglesias BV, Li Y, Colino J, Snapper CM, Hollingshead SK, Pham G, Gosselin DR, Gosselin EJ.

Infect Immun. 2012 Mar;80(3):1166-80. doi: 10.1128/IAI.05511-11. Epub 2011 Dec 12.


DNA vaccines based on genetically detoxified derivatives of pneumolysin fail to protect mice against challenge with Streptococcus pneumoniae.

Ferreira DM, Arêas AP, Darrieux M, Leite LC, Miyaji EN.

FEMS Immunol Med Microbiol. 2006 Mar;46(2):291-7.

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