Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 160


The DNA-damage effector checkpoint kinase 1 is essential for chromosome segregation and cytokinesis.

Peddibhotla S, Lam MH, Gonzalez-Rimbau M, Rosen JM.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5159-64. doi: 10.1073/pnas.0806671106. Epub 2009 Mar 16.


Chking and executing cell division to prevent genomic instability.

Peddibhotla S, Rosen JM.

Cell Cycle. 2009 Aug;8(15):2339-42. Epub 2009 Aug 3.


Context-dependent cell cycle checkpoint abrogation by a novel kinase inhibitor.

Massey AJ, Borgognoni J, Bentley C, Foloppe N, Fiumana A, Walmsley L.

PLoS One. 2010 Oct 18;5(10):e13123. doi: 10.1371/journal.pone.0013123.


DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint.

Huang X, Tran T, Zhang L, Hatcher R, Zhang P.

Proc Natl Acad Sci U S A. 2005 Jan 25;102(4):1065-70. Epub 2005 Jan 13.


Exercising restraints: role of Chk1 in regulating the onset and progression of unperturbed mitosis in vertebrate cells.

Zachos G, Gillespie DA.

Cell Cycle. 2007 Apr 1;6(7):810-3. Epub 2007 Apr 22. Review.


Chk1 is required for spindle checkpoint function.

Zachos G, Black EJ, Walker M, Scott MT, Vagnarelli P, Earnshaw WC, Gillespie DA.

Dev Cell. 2007 Feb;12(2):247-60.


Mitotic kinases: the key to duplication, segregation, and cytokinesis errors, chromosomal instability, and oncogenesis.

Li JJ, Li SA.

Pharmacol Ther. 2006 Sep;111(3):974-84. Epub 2006 Apr 17. Review.


Checkpoint kinase 1 (Chk1) is required for mitotic progression through negative regulation of polo-like kinase 1 (Plk1).

Tang J, Erikson RL, Liu X.

Proc Natl Acad Sci U S A. 2006 Aug 8;103(32):11964-9. Epub 2006 Jul 27.


DNA replication stress in CHK1-depleted tumour cells triggers premature (S-phase) mitosis through inappropriate activation of Aurora kinase B.

Zuazua-Villar P, Rodriguez R, Gagou ME, Eyers PA, Meuth M.

Cell Death Dis. 2014 May 22;5:e1253. doi: 10.1038/cddis.2014.231.


Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1).

Trakala M, Fernández-Miranda G, Pérez de Castro I, Heeschen C, Malumbres M.

Cell Cycle. 2013 Apr 1;12(7):1030-41. doi: 10.4161/cc.24004. Epub 2013 Feb 21.


A role for Chk2 in DNA damage induced mitotic delays in human colorectal cancer cells.

Varmark H, Kwak S, Theurkauf WE.

Cell Cycle. 2010 Jan 15;9(2):312-20. Epub 2010 Jan 23.


DNA damage control: regulation and functions of checkpoint kinase 1.

Smits VA, Gillespie DA.

FEBS J. 2015 Oct;282(19):3681-92. doi: 10.1111/febs.13387. Epub 2015 Aug 13. Review.


Chk1: a double agent in cell cycle checkpoints.

Yu H.

Dev Cell. 2007 Feb;12(2):167-8.


RPA phosphorylation facilitates mitotic exit in response to mitotic DNA damage.

Anantha RW, Sokolova E, Borowiec JA.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12903-8. doi: 10.1073/pnas.0803001105. Epub 2008 Aug 22.


ATR and a Chk1-Aurora B pathway coordinate postmitotic genome surveillance with cytokinetic abscission.

Mackay DR, Ullman KS.

Mol Biol Cell. 2015 Jun 15;26(12):2217-26. doi: 10.1091/mbc.E14-11-1563. Epub 2015 Apr 22.


Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

Morrow CJ, Tighe A, Johnson VL, Scott MI, Ditchfield C, Taylor SS.

J Cell Sci. 2005 Aug 15;118(Pt 16):3639-52. Epub 2005 Jul 26.


Chk1-Mad2 interaction: a crosslink between the DNA damage checkpoint and the mitotic spindle checkpoint.

Chilà R, Celenza C, Lupi M, Damia G, Carrassa L.

Cell Cycle. 2013 Apr 1;12(7):1083-90. doi: 10.4161/cc.24090. Epub 2013 Mar 1.


Phosphatase inhibitor-2 balances protein phosphatase 1 and aurora B kinase for chromosome segregation and cytokinesis in human retinal epithelial cells.

Wang W, Stukenberg PT, Brautigan DL.

Mol Biol Cell. 2008 Nov;19(11):4852-62. doi: 10.1091/mbc.E08-05-0460. Epub 2008 Aug 20.

Supplemental Content

Support Center