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Items: 1 to 20 of 81

1.

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

Ju J, Li W, Yuan Q, Peters NR, Hoffmann FM, Rajski SR, Osada H, Shen B.

Org Lett. 2009 Apr 2;11(7):1639-42. doi: 10.1021/ol900293j.

2.

Characterization of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus unveiling new insights into dialkylmaleic anhydride and polyketide biosynthesis.

Li W, Ju J, Rajski SR, Osada H, Shen B.

J Biol Chem. 2008 Oct 17;283(42):28607-17. doi: 10.1074/jbc.M804279200. Epub 2008 Aug 15.

3.
5.

The selective inhibition of phosphatases by natural toxins: the anhydride domain of tautomycin is not a primary factor in controlling PP1/PP2A selectivity.

Liu W, Sheppeck JE 2nd, Colby DA, Huang HB, Nairn AC, Chamberlin AR.

Bioorg Med Chem Lett. 2003 May 5;13(9):1597-600.

PMID:
12699763
6.

Synthesis of [18,19,21,22-(13)C4]-labeled tautomycin as an NMR probe of protein phosphatase inhibitor.

Isobe M, Kurono M, Tsuboi K, Takai A.

Chem Asian J. 2007 Mar 5;2(3):377-85.

PMID:
17441173
8.

Protein phosphatase inhibitory activity of tautomycin photoaffinity probes evaluated at femto-molar level.

Sydnes MO, Kuse M, Kurono M, Shimomura A, Ohinata H, Takai A, Isobe M.

Bioorg Med Chem. 2008 Feb 15;16(4):1747-55. Epub 2007 Nov 17.

PMID:
18061458
9.

Antifungal activity of tautomycin and related compounds against Sclerotinia sclerotiorum.

Chen X, Zhu X, Ding Y, Shen Y.

J Antibiot (Tokyo). 2011 Aug;64(8):563-9. doi: 10.1038/ja.2011.55. Epub 2011 Jul 20.

PMID:
21772304
10.

Different moieties of tautomycin involved in protein phosphatase inhibition and induction of apoptosis.

Kawamura T, Matsuzawa S, Mizuno Y, Kikuchi K, Oikawa H, Oikawa M, Ubukata M, Ichihara A.

Biochem Pharmacol. 1998 Apr 1;55(7):995-1003.

PMID:
9605423
11.

Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

Luo Y, Li W, Ju J, Yuan Q, Peters NR, Hoffmann FM, Huang SX, Bugni TS, Rajski S, Osada H, Shen B.

J Am Chem Soc. 2010 May 19;132(19):6663-71. doi: 10.1021/ja9082446.

12.

Synthesis and stereochemistry of the terminal spiroketal domain of the phosphatase inhibitor dinophysistoxin-2.

Forsyth CJ, Wang C.

Bioorg Med Chem Lett. 2008 May 15;18(10):3043-6. doi: 10.1016/j.bmcl.2008.01.002. Epub 2008 Jan 8.

PMID:
18226903
13.

Tautomycin's interactions with protein phosphatase 1.

Sydnes MO, Isobe M.

Chem Asian J. 2010 Mar 1;5(3):410-20. doi: 10.1002/asia.200900394. Review.

PMID:
20013999
14.

The spiroketals containing a benzyloxymethyl moiety at C8 position showed the most potent apoptosis-inducing activity.

Mitsuhashi S, Shima H, Kawamura T, Kikuchi K, Oikawa M, Ichihara A, Oikawa H.

Bioorg Med Chem Lett. 1999 Jul 19;9(14):2007-12.

PMID:
10450971
15.

Total synthesis and confirmation of the revised structures of azaspiracid-2 and azaspiracid-3.

Nicolaou KC, Frederick MO, Petrovic G, Cole KP, Loizidou EZ.

Angew Chem Int Ed Engl. 2006 Apr 10;45(16):2609-15. No abstract available.

PMID:
16548033
16.

Stereoselective total synthesis of (-)-spirofungin A by utilising hydrogen-bond controlled spiroketalisation.

Lynch JE, Zanatta SD, White JM, Rizzacasa MA.

Chemistry. 2011 Jan 3;17(1):297-304. doi: 10.1002/chem.201002501. Epub 2010 Dec 10.

PMID:
21207625
17.

Reveromycins revealed: new polyketide spiroketals from Australian marine-derived and terrestrial Streptomyces spp. A case of natural products vs. artifacts.

Fremlin L, Farrugia M, Piggott AM, Khalil Z, Lacey E, Capon RJ.

Org Biomol Chem. 2011 Feb 21;9(4):1201-11. doi: 10.1039/c0ob00654h. Epub 2010 Dec 14.

PMID:
21152660
18.

Synthesis of the C1-C21 domain of azaspiracids-1 and -3.

Zhang Z, Ding Y, Xu J, Chen Y, Forsyth CJ.

Org Lett. 2013 May 17;15(10):2338-41. doi: 10.1021/ol400487e. Epub 2013 Apr 29.

PMID:
23627769
19.

Structure-activity relationship for FR901464: a versatile method for the conversion and preparation of biologically active biotinylated probes.

Motoyoshi H, Horigome M, Ishigami K, Yoshida T, Horinouchi S, Yoshida M, Watanabe H, Kitahara T.

Biosci Biotechnol Biochem. 2004 Oct;68(10):2178-82.

20.

A new model of the tautomycin-PP1 complex that is not analogous to the corresponding okadaic acid structure.

Colby DA, Liu W, Sheppeck JE, Huang HB, Nairn AC, Chamberlin AR.

Bioorg Med Chem Lett. 2003 May 5;13(9):1601-5.

PMID:
12699764

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