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Items: 1 to 20 of 108

1.

Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Assmann A, Ueki K, Winnay JN, Kadowaki T, Kulkarni RN.

Mol Cell Biol. 2009 Jun;29(11):3219-28. doi: 10.1128/MCB.01489-08. Epub 2009 Mar 9.

2.

High glucose induces suppression of insulin signalling and apoptosis via upregulation of endogenous IL-1beta and suppressor of cytokine signalling-1 in mouse pancreatic beta cells.

Venieratos PD, Drossopoulou GI, Kapodistria KD, Tsilibary EC, Kitsiou PV.

Cell Signal. 2010 May;22(5):791-800. doi: 10.1016/j.cellsig.2010.01.003. Epub 2010 Jan 11.

PMID:
20067833
3.

Genetic analysis of type-1 insulin-like growth factor receptor signaling through insulin receptor substrate-1 and -2 in pancreatic beta cells.

Xuan S, Szabolcs M, Cinti F, Perincheri S, Accili D, Efstratiadis A.

J Biol Chem. 2010 Dec 24;285(52):41044-50. doi: 10.1074/jbc.M110.144790. Epub 2010 Oct 14.

4.

Glucose Induces Mouse β-Cell Proliferation via IRS2, MTOR, and Cyclin D2 but Not the Insulin Receptor.

Stamateris RE, Sharma RB, Kong Y, Ebrahimpour P, Panday D, Ranganath P, Zou B, Levitt H, Parambil NA, O'Donnell CP, García-Ocaña A, Alonso LC.

Diabetes. 2016 Apr;65(4):981-95. doi: 10.2337/db15-0529. Epub 2016 Jan 6.

5.

Glucose and fatty acids synergize to promote B-cell apoptosis through activation of glycogen synthase kinase 3β independent of JNK activation.

Tanabe K, Liu Y, Hasan SD, Martinez SC, Cras-Méneur C, Welling CM, Bernal-Mizrachi E, Tanizawa Y, Rhodes CJ, Zmuda E, Hai T, Abumrad NA, Permutt MA.

PLoS One. 2011 Apr 26;6(4):e18146. doi: 10.1371/journal.pone.0018146.

6.

Nuclear Export of FoxO1 Is Associated with ERK Signaling in β-Cells Lacking Insulin Receptors.

Mezza T, Shirakawa J, Martinez R, Hu J, Giaccari A, Kulkarni RN.

J Biol Chem. 2016 Oct 7;291(41):21485-21495. Epub 2016 Aug 17.

7.

Role of the TSC1-TSC2 complex in the integration of insulin and glucose signaling involved in pancreatic beta-cell proliferation.

Bartolomé A, Guillén C, Benito M.

Endocrinology. 2010 Jul;151(7):3084-94. doi: 10.1210/en.2010-0048. Epub 2010 Apr 28.

PMID:
20427478
8.

Differential mitogenic signaling in insulin receptor-deficient fetal pancreatic beta-cells.

Guillen C, Navarro P, Robledo M, Valverde AM, Benito M.

Endocrinology. 2006 Apr;147(4):1959-68. Epub 2006 Jan 5.

9.

Metformin-mediated growth inhibition involves suppression of the IGF-I receptor signalling pathway in human pancreatic cancer cells.

Karnevi E, Said K, Andersson R, Rosendahl AH.

BMC Cancer. 2013 May 10;13:235. doi: 10.1186/1471-2407-13-235.

10.

Nitric oxide mediates the survival action of IGF-1 and insulin in pancreatic beta cells.

Cahuana GM, Tejedo JR, Hmadcha A, Ramírez R, Cuesta AL, Soria B, Martin F, Bedoya FJ.

Cell Signal. 2008 Feb;20(2):301-10. Epub 2007 Oct 12.

PMID:
18023142
12.

Effect of zinc on regulation of insulin-like growth factor signaling in human androgen-independent prostate cancer cells.

Banudevi S, Senthilkumar K, Sharmila G, Arunkumar R, Vijayababu MR, Arunakaran J.

Clin Chim Acta. 2010 Feb;411(3-4):172-8. doi: 10.1016/j.cca.2009.10.023. Epub 2009 Nov 11.

PMID:
19913001
13.

Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.

Martinez SC, Cras-Méneur C, Bernal-Mizrachi E, Permutt MA.

Diabetes. 2006 Jun;55(6):1581-91.

14.

Activation of the insulin-like growth factor 1 signaling pathway by the antiapoptotic agents aurintricarboxylic acid and evans blue.

Beery R, Haimsohn M, Wertheim N, Hemi R, Nir U, Karasik A, Kanety H, Geier A.

Endocrinology. 2001 Jul;142(7):3098-107.

PMID:
11416032
15.

Palmitate affects insulin receptor phosphorylation and intracellular insulin signal in a pancreatic alpha-cell line.

Piro S, Maniscalchi ET, Monello A, Pandini G, Mascali LG, Rabuazzo AM, Purrello F.

Endocrinology. 2010 Sep;151(9):4197-206. doi: 10.1210/en.2009-1472. Epub 2010 Jun 23.

PMID:
20573722
16.

Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells.

D'Alessandris C, Andreozzi F, Federici M, Cardellini M, Brunetti A, Ranalli M, Del Guerra S, Lauro D, Del Prato S, Marchetti P, Lauro R, Sesti G.

FASEB J. 2004 Jun;18(9):959-61. Epub 2004 Apr 1.

PMID:
15059979
17.

EGF regulates survivin stability through the Raf-1/ERK pathway in insulin-secreting pancreatic β-cells.

Wang H, Gambosova K, Cooper ZA, Holloway MP, Kassai A, Izquierdo D, Cleveland K, Boney CM, Altura RA.

BMC Mol Biol. 2010 Aug 31;11:66. doi: 10.1186/1471-2199-11-66.

20.

PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.

Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.

Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3687-98. doi: 10.1167/iovs.07-1455. Epub 2008 Apr 17.

PMID:
18421086

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