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Items: 1 to 20 of 114

1.

Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor.

Harris DM, Westerlaken I, Schipper D, van der Krogt ZA, Gombert AK, Sutherland J, Raamsdonk LM, van den Berg MA, Bovenberg RA, Pronk JT, Daran JM.

Metab Eng. 2009 Mar;11(2):125-37. doi: 10.1016/j.ymben.2008.12.003.

PMID:
19271269
2.

Expression of the transporter encoded by the cefT gene of Acremonium chrysogenum increases cephalosporin production in Penicillium chrysogenum.

Nijland JG, Kovalchuk A, van den Berg MA, Bovenberg RA, Driessen AJ.

Fungal Genet Biol. 2008 Oct;45(10):1415-21. doi: 10.1016/j.fgb.2008.07.008. Epub 2008 Jul 22.

PMID:
18691664
3.

Metabolic engineering of β-oxidation in Penicillium chrysogenum for improved semi-synthetic cephalosporin biosynthesis.

Veiga T, Gombert AK, Landes N, Verhoeven MD, Kiel JA, Krikken AM, Nijland JG, Touw H, Luttik MA, van der Toorn JC, Driessen AJ, Bovenberg RA, van den Berg MA, van der Klei IJ, Pronk JT, Daran JM.

Metab Eng. 2012 Jul;14(4):437-48. doi: 10.1016/j.ymben.2012.02.004. Epub 2012 Feb 22.

4.

Production of cephalosporin intermediates by feeding adipic acid to recombinant Penicillium chrysogenum strains expressing ring expansion activity.

Crawford L, Stepan AM, McAda PC, Rambosek JA, Conder MJ, Vinci VA, Reeves CD.

Biotechnology (N Y). 1995 Jan;13(1):58-62.

PMID:
9634750
6.
8.

Environmentally safe production of 7-aminodeacetoxycephalosporanic acid (7-ADCA) using recombinant strains of Acremonium chrysogenum.

Velasco J, Luis Adrio J, Angel Moreno M, Díez B, Soler G, Barredo JL.

Nat Biotechnol. 2000 Aug;18(8):857-61.

PMID:
10932155
10.

The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics.

Koetsier MJ, Gombert AK, Fekken S, Bovenberg RA, van den Berg MA, Kiel JA, Jekel PA, Janssen DB, Pronk JT, van der Klei IJ, Daran JM.

Fungal Genet Biol. 2010 Jan;47(1):33-42. doi: 10.1016/j.fgb.2009.10.003.

PMID:
19833221
12.
13.

Functional characterization of the oxaloacetase encoding gene and elimination of oxalate formation in the β-lactam producer Penicillium chrysogenum.

Gombert AK, Veiga T, Puig-Martinez M, Lamboo F, Nijland JG, Driessen AJ, Pronk JT, Daran JM.

Fungal Genet Biol. 2011 Aug;48(8):831-9. doi: 10.1016/j.fgb.2011.04.007. Epub 2011 Apr 29.

14.

New aspects of genes and enzymes for beta-lactam antibiotic biosynthesis.

Martín JF.

Appl Microbiol Biotechnol. 1998 Jul;50(1):1-15. Review.

PMID:
9720195
15.
16.

Novel genes involved in cephalosporin biosynthesis: the three-component isopenicillin N epimerase system.

Martín JF, Ullán RV, Casqueiro J.

Adv Biochem Eng Biotechnol. 2004;88:91-109. Review.

PMID:
15719553
17.

RNA-silencing in Penicillium chrysogenum and Acremonium chrysogenum: validation studies using beta-lactam genes expression.

Ullán RV, Godio RP, Teijeira F, Vaca I, García-Estrada C, Feltrer R, Kosalkova K, Martín JF.

J Microbiol Methods. 2008 Oct;75(2):209-18. doi: 10.1016/j.mimet.2008.06.001. Epub 2008 Jun 12.

PMID:
18590779
18.
19.

Transcriptional and bioinformatic analysis of the 56.8 kb DNA region amplified in tandem repeats containing the penicillin gene cluster in Penicillium chrysogenum.

Fierro F, García-Estrada C, Castillo NI, Rodríguez R, Velasco-Conde T, Martín JF.

Fungal Genet Biol. 2006 Sep;43(9):618-29. Epub 2006 May 18.

PMID:
16713314
20.

Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production.

Harris DM, van der Krogt ZA, Klaassen P, Raamsdonk LM, Hage S, van den Berg MA, Bovenberg RA, Pronk JT, Daran JM.

BMC Genomics. 2009 Feb 10;10:75. doi: 10.1186/1471-2164-10-75.

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