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Items: 1 to 20 of 268

1.

A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.

Luallen RJ, Fu H, Agrawal-Gamse C, Mboudjeka I, Huang W, Lee FH, Wang LX, Doms RW, Geng Y.

J Virol. 2009 May;83(10):4861-70. doi: 10.1128/JVI.02537-08. Epub 2009 Mar 4.

2.

An engineered Saccharomyces cerevisiae strain binds the broadly neutralizing human immunodeficiency virus type 1 antibody 2G12 and elicits mannose-specific gp120-binding antibodies.

Luallen RJ, Lin J, Fu H, Cai KK, Agrawal C, Mboudjeka I, Lee FH, Montefiori D, Smith DF, Doms RW, Geng Y.

J Virol. 2008 Jul;82(13):6447-57. doi: 10.1128/JVI.00412-08. Epub 2008 Apr 23.

3.

Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans.

Agrawal-Gamse C, Luallen RJ, Liu B, Fu H, Lee FH, Geng Y, Doms RW.

J Virol. 2011 Jan;85(1):470-80. doi: 10.1128/JVI.01349-10. Epub 2010 Oct 20.

4.

Identification of the optimal DC-SIGN binding site on human immunodeficiency virus type 1 gp120.

Hong PW, Nguyen S, Young S, Su SV, Lee B.

J Virol. 2007 Aug;81(15):8325-36. Epub 2007 May 23.

5.

The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of alpha1-->2 mannose residues on the outer face of gp120.

Scanlan CN, Pantophlet R, Wormald MR, Ollmann Saphire E, Stanfield R, Wilson IA, Katinger H, Dwek RA, Rudd PM, Burton DR.

J Virol. 2002 Jul;76(14):7306-21.

6.

Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strains.

Luallen RJ, Agrawal-Gamse C, Fu H, Smith DF, Doms RW, Geng Y.

Glycobiology. 2010 Mar;20(3):280-6. doi: 10.1093/glycob/cwp184. Epub 2009 Nov 17.

8.

A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120.

Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR.

J Virol. 2008 Jul;82(13):6359-68. doi: 10.1128/JVI.00293-08. Epub 2008 Apr 23.

9.

Antibodies elicited by yeast glycoproteins recognize HIV-1 virions and potently neutralize virions with high mannose N-glycans.

Zhang H, Fu H, Luallen RJ, Liu B, Lee FH, Doms RW, Geng Y.

Vaccine. 2015 Sep 22;33(39):5140-7. doi: 10.1016/j.vaccine.2015.08.012. Epub 2015 Aug 13.

10.

The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

Sanders RW, Venturi M, Schiffner L, Kalyanaraman R, Katinger H, Lloyd KO, Kwong PD, Moore JP.

J Virol. 2002 Jul;76(14):7293-305.

11.

Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN.

Wang SK, Liang PH, Astronomo RD, Hsu TL, Hsieh SL, Burton DR, Wong CH.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3690-5. doi: 10.1073/pnas.0712326105. Epub 2008 Feb 29.

12.

Inhibition of HIV Env binding to cellular receptors by monoclonal antibody 2G12 as probed by Fc-tagged gp120.

Binley JM, Ngo-Abdalla S, Moore P, Bobardt M, Chatterji U, Gallay P, Burton DR, Wilson IA, Elder JH, de Parseval A.

Retrovirology. 2006 Jul 3;3:39. Erratum in: Retrovirology. 2007;4:23.

13.

Actinohivin, a broadly neutralizing prokaryotic lectin, inhibits HIV-1 infection by specifically targeting high-mannose-type glycans on the gp120 envelope.

Hoorelbeke B, Huskens D, Férir G, François KO, Takahashi A, Van Laethem K, Schols D, Tanaka H, Balzarini J.

Antimicrob Agents Chemother. 2010 Aug;54(8):3287-301. doi: 10.1128/AAC.00254-10. Epub 2010 May 24.

14.

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1.

Trkola A, Purtscher M, Muster T, Ballaun C, Buchacher A, Sullivan N, Srinivasan K, Sodroski J, Moore JP, Katinger H.

J Virol. 1996 Feb;70(2):1100-8.

15.

Gold nanoparticles coated with oligomannosides of HIV-1 glycoprotein gp120 mimic the carbohydrate epitope of antibody 2G12.

Marradi M, Di Gianvincenzo P, Enríquez-Navas PM, Martínez-Ávila OM, Chiodo F, Yuste E, Angulo J, Penadés S.

J Mol Biol. 2011 Jul 29;410(5):798-810. doi: 10.1016/j.jmb.2011.03.042. Epub 2011 Mar 25.

PMID:
21440555
16.

Concanavalin A binding to HIV envelope protein is less sensitive to mutations in glycosylation sites than monoclonal antibody 2G12.

Pashov A, MacLeod S, Saha R, Perry M, VanCott TC, Kieber-Emmons T.

Glycobiology. 2005 Oct;15(10):994-1001. Epub 2005 May 25.

PMID:
15917430
17.

Efficient capture of antibody neutralized HIV-1 by cells expressing DC-SIGN and transfer to CD4+ T lymphocytes.

van Montfort T, Nabatov AA, Geijtenbeek TB, Pollakis G, Paxton WA.

J Immunol. 2007 Mar 1;178(5):3177-85.

18.
20.

Identification of the DC-SIGN-interactive domains on the envelope glycoprotein of HIV-1 CRF07_BC.

Liao CF, Wang SF, Lin YT, Ho DD, Chen YM.

AIDS Res Hum Retroviruses. 2011 Aug;27(8):831-9. doi: 10.1089/AID.2010.0215. Epub 2011 Jan 17.

PMID:
21142800

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