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Items: 1 to 20 of 945

1.

rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population.

Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Mar;104(3):665-72. doi: 10.1038/ajg.2008.65. Epub 2009 Feb 3.

PMID:
19262523
2.

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

Glas J, Konrad A, Schmechel S, Dambacher J, Seiderer J, Schroff F, Wetzke M, Roeske D, Török HP, Tonenchi L, Pfennig S, Haller D, Griga T, Klein W, Epplen JT, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Mussack T, Folwaczny M, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2008 Mar;103(3):682-91. Epub 2007 Dec 20.

PMID:
18162085
3.

Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease.

Török HP, Glas J, Endres I, Tonenchi L, Teshome MY, Wetzke M, Klein W, Lohse P, Ochsenkühn T, Folwaczny M, Göke B, Folwaczny C, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1723-33. doi: 10.1038/ajg.2009.184. Epub 2009 May 19.

PMID:
19455129
4.

Confirmation of association of IRGM and NCF4 with ileal Crohn's disease in a population-based cohort.

Roberts RL, Hollis-Moffatt JE, Gearry RB, Kennedy MA, Barclay ML, Merriman TR.

Genes Immun. 2008 Sep;9(6):561-5. doi: 10.1038/gene.2008.49. Epub 2008 Jun 26.

PMID:
18580884
5.

Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD.

Seiderer J, Elben I, Diegelmann J, Glas J, Stallhofer J, Tillack C, Pfennig S, Jürgens M, Schmechel S, Konrad A, Göke B, Ochsenkühn T, Müller-Myhsok B, Lohse P, Brand S.

Inflamm Bowel Dis. 2008 Apr;14(4):437-45.

PMID:
18088064
6.

Contribution of the novel inflammatory bowel disease gene IL23R to disease susceptibility and phenotype.

Cummings JR, Ahmad T, Geremia A, Beckly J, Cooney R, Hancock L, Pathan S, Guo C, Cardon LR, Jewell DP.

Inflamm Bowel Dis. 2007 Sep;13(9):1063-8.

PMID:
17508420
7.

Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease.

Glas J, Stallhofer J, Ripke S, Wetzke M, Pfennig S, Klein W, Epplen JT, Griga T, Schiemann U, Lacher M, Koletzko S, Folwaczny M, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Brand S.

Am J Gastroenterol. 2009 Jul;104(7):1737-44. doi: 10.1038/ajg.2009.163. Epub 2009 May 19.

PMID:
19455118
8.

Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population.

Lappalainen M, Halme L, Turunen U, Saavalainen P, Einarsdottir E, Färkkilä M, Kontula K, Paavola-Sakki P.

Inflamm Bowel Dis. 2008 Aug;14(8):1118-24. doi: 10.1002/ibd.20431.

PMID:
18338763
9.

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

Glas J, Seiderer J, Wetzke M, Konrad A, Török HP, Schmechel S, Tonenchi L, Grassl C, Dambacher J, Pfennig S, Maier K, Griga T, Klein W, Epplen JT, Schiemann U, Folwaczny C, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Folwaczny M, Mussack T, Brand S.

PLoS One. 2007 Sep 5;2(9):e819.

10.

NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in Canadian children and young adults.

Amre DK, Mack DR, Israel D, Krupoves A, Costea I, Lambrette P, Grimard G, Dong J, Levy E.

Inflamm Bowel Dis. 2012 Mar;18(3):529-35. doi: 10.1002/ibd.21708. Epub 2011 Apr 6.

PMID:
21472827
11.

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.

Waller S, Tremelling M, Bredin F, Godfrey L, Howson J, Parkes M.

Gut. 2006 Jun;55(6):809-14. Epub 2005 Dec 16.

12.

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

Weersma RK, Zhou L, Nolte IM, van der Steege G, van Dullemen HM, Oosterom E, Bok L, Peppelenbosch MP, Faber KN, Kleibeuker JH, Dijkstra G.

Inflamm Bowel Dis. 2008 Dec;14(12):1615-22. doi: 10.1002/ibd.20610.

PMID:
18668679
13.

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background.

Glas J, Wagner J, Seiderer J, Olszak T, Wetzke M, Beigel F, Tillack C, Stallhofer J, Friedrich M, Steib C, Göke B, Ochsenkühn T, Karbalai N, Diegelmann J, Czamara D, Brand S.

PLoS One. 2012;7(3):e33682. doi: 10.1371/journal.pone.0033682. Epub 2012 Mar 21.

14.

DLG5 variants in inflammatory bowel disease.

Büning C, Geerdts L, Fiedler T, Gentz E, Pitre G, Reuter W, Luck W, Buhner S, Molnar T, Nagy F, Lonovics J, Dignass A, Landt O, Nickel R, Genschel J, Lochs H, Schmidt HH, Witt H.

Am J Gastroenterol. 2006 Apr;101(4):786-92. Epub 2006 Feb 22.

PMID:
16494592
15.

Linking genetic susceptibility to Crohn's disease with Th17 cell function: IL-22 serum levels are increased in Crohn's disease and correlate with disease activity and IL23R genotype status.

Schmechel S, Konrad A, Diegelmann J, Glas J, Wetzke M, Paschos E, Lohse P, Göke B, Brand S.

Inflamm Bowel Dis. 2008 Feb;14(2):204-12.

PMID:
18022867
16.

Association of NOD2/CARD15 variants with Crohn's disease in a Greek population.

Gazouli M, Zacharatos P, Mantzaris GJ, Barbatis C, Ikonomopoulos I, Archimandritis AJ, Lukas JC, Papalambros E, Gorgoulis V.

Eur J Gastroenterol Hepatol. 2004 Nov;16(11):1177-82.

PMID:
15489579
17.

Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease.

Tosa M, Negoro K, Kinouchi Y, Abe H, Nomura E, Takagi S, Aihara H, Oomori S, Sugimura M, Takahashi K, Hiwatashi N, Takahashi S, Shimosegawa T.

Scand J Gastroenterol. 2006 Jan;41(1):48-53.

PMID:
16373276
18.

Association between genetic variants in myosin IXB and Crohn's disease.

Cooney R, Cummings JR, Pathan S, Beckly J, Geremia A, Hancock L, Guo C, Morris A, Jewell DP.

Inflamm Bowel Dis. 2009 Jul;15(7):1014-21. doi: 10.1002/ibd.20885.

PMID:
19235913
19.

Positive association of genetic variants in the upstream region of NKX2-3 with Crohn's disease in Japanese patients.

Yamazaki K, Takahashi A, Takazoe M, Kubo M, Onouchi Y, Fujino A, Kamatani N, Nakamura Y, Hata A.

Gut. 2009 Feb;58(2):228-32. doi: 10.1136/gut.2007.140764. Epub 2008 Oct 20.

PMID:
18936107
20.

Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.

Büning C, Schmidt HH, Molnar T, De Jong DJ, Fiedler T, Bühner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Büttner J, Lochs H, Witt H.

Aliment Pharmacol Ther. 2007 Oct 1;26(7):1025-33.

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