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Items: 1 to 20 of 374

1.

Assessing the metabolic competence of sandwich-cultured mouse primary hepatocytes.

Mathijs K, Kienhuis AS, Brauers KJ, Jennen DG, Lahoz A, Kleinjans JC, van Delft JH.

Drug Metab Dispos. 2009 Jun;37(6):1305-11. doi: 10.1124/dmd.108.025775.

2.

A sandwich-cultured rat hepatocyte system with increased metabolic competence evaluated by gene expression profiling.

Kienhuis AS, Wortelboer HM, Maas WJ, van Herwijnen M, Kleinjans JC, van Delft JH, Stierum RH.

Toxicol In Vitro. 2007 Aug;21(5):892-901.

PMID:
17336492
3.

Effects of L-proline on phase I and phase II xenobiotic biotransformation capacities of rat and human hepatocytes in long-term collagen gel cultures.

Beken S, De Smet K, Depreter M, Roels F, Vercruysse A, Rogiers V.

Altern Lab Anim. 2001 Jan-Feb;29(1):35-53.

4.
5.

The suitability of hepatocyte culture models to study various aspects of drug metabolism.

Nussler AK, Wang A, Neuhaus P, Fischer J, Yuan J, Liu L, Zeilinger K, Gerlach J, Arnold PJ, Albrecht W.

ALTEX. 2001;18(2):91-101.

PMID:
11378681
6.

Comparison of coumarin-induced toxicity between sandwich-cultured primary rat hepatocytes and rats in vivo: a toxicogenomics approach.

Kienhuis AS, Wortelboer HM, Hoflack JC, Moonen EJ, Kleinjans JC, van Ommen B, van Delft JH, Stierum RH.

Drug Metab Dispos. 2006 Dec;34(12):2083-90.

7.
8.

Collagen type I gel cultures of adult rat hepatocytes as a screening induction model for cytochrome P450-dependent enzymes.

De Smet K, Cavin C, Vercruysse A, Rogiers V.

Altern Lab Anim. 2001 Mar-Apr;29(2):179-92.

9.

Primary rat hepatocytes as in vitro system for gene expression studies: comparison of sandwich, Matrigel and 2D cultures.

Schug M, Heise T, Bauer A, Storm D, Blaszkewicz M, Bedawy E, Brulport M, Geppert B, Hermes M, Föllmann W, Rapp K, Maccoux L, Schormann W, Appel KE, Oberemm A, Gundert-Remy U, Hengstler JG.

Arch Toxicol. 2008 Dec;82(12):923-31. doi: 10.1007/s00204-008-0375-x.

PMID:
18987846
10.

Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.

Tuschl G, Hrach J, Walter Y, Hewitt PG, Mueller SO.

Chem Biol Interact. 2009 Sep 14;181(1):124-37. doi: 10.1016/j.cbi.2009.05.015.

PMID:
19482013
11.

Evaluation of the effect of culture configuration on morphology, survival time, antioxidant status and metabolic capacities of cultured rat hepatocytes.

Richert L, Binda D, Hamilton G, Viollon-Abadie C, Alexandre E, Bigot-Lasserre D, Bars R, Coassolo P, LeCluyse E.

Toxicol In Vitro. 2002 Feb;16(1):89-99.

PMID:
11812644
13.
14.

Temporal gene expression analysis of monolayer cultured rat hepatocytes.

Baker TK, Carfagna MA, Gao H, Dow ER, Li Q, Searfoss GH, Ryan TP.

Chem Res Toxicol. 2001 Sep;14(9):1218-31.

PMID:
11559036
15.

Network analysis of primary hepatocyte dedifferentiation using a shotgun proteomics approach.

Rowe C, Goldring CE, Kitteringham NR, Jenkins RE, Lane BS, Sanderson C, Elliott V, Platt V, Metcalfe P, Park BK.

J Proteome Res. 2010 May 7;9(5):2658-68. doi: 10.1021/pr1001687. Erratum in: J Proteome Res. 2010 Aug 6;9(8):4313-4.

PMID:
20373825
17.

Constitutive and inducible expression of CYP enzymes in immortal hepatocytes derived from SV40 transgenic mice.

Donato MT, Klocke R, Castell JV, Stenzel K, Paul D, Gómez-Lechón MJ.

Xenobiotica. 2003 May;33(5):459-73.

PMID:
12746103
18.

Human hepatocyte--a model for toxicological studies. Functional and biochemical characterization.

Modrianský M, Ulrichová J, Bachleda P, Anzenbacher P, Anzenbacherová E, Walterová D, Simánek V.

Gen Physiol Biophys. 2000 Jun;19(2):223-35.

PMID:
11156444
19.
20.

Interspecies difference in liver-specific functions and biotransformation of testosterone of primary rat, porcine and human hepatocyte in an organotypical sandwich culture.

Langsch A, Giri S, Acikgöz A, Jasmund I, Frericks B, Bader A.

Toxicol Lett. 2009 Aug 10;188(3):173-9. doi: 10.1016/j.toxlet.2009.03.022.

PMID:
19428196
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