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Items: 1 to 20 of 139

1.

Association between genes of Disrupted in schizophrenia 1 (DISC1) interactors and schizophrenia supports the role of the DISC1 pathway in the etiology of major mental illnesses.

Tomppo L, Hennah W, Lahermo P, Loukola A, Tuulio-Henriksson A, Suvisaari J, Partonen T, Ekelund J, Lönnqvist J, Peltonen L.

Biol Psychiatry. 2009 Jun 15;65(12):1055-62. doi: 10.1016/j.biopsych.2009.01.014. Epub 2009 Feb 28.

2.

Families with the risk allele of DISC1 reveal a link between schizophrenia and another component of the same molecular pathway, NDE1.

Hennah W, Tomppo L, Hiekkalinna T, Palo OM, Kilpinen H, Ekelund J, Tuulio-Henriksson A, Silander K, Partonen T, Paunio T, Terwilliger JD, Lönnqvist J, Peltonen L.

Hum Mol Genet. 2007 Mar 1;16(5):453-62. Epub 2006 Dec 21.

PMID:
17185386
3.

Elucidating the relationship between DISC1, NDEL1 and NDE1 and the risk for schizophrenia: evidence of epistasis and competitive binding.

Burdick KE, Kamiya A, Hodgkinson CA, Lencz T, DeRosse P, Ishizuka K, Elashvili S, Arai H, Goldman D, Sawa A, Malhotra AK.

Hum Mol Genet. 2008 Aug 15;17(16):2462-73. doi: 10.1093/hmg/ddn146. Epub 2008 May 10.

4.

Haplotype transmission analysis provides evidence of association for DISC1 to schizophrenia and suggests sex-dependent effects.

Hennah W, Varilo T, Kestilä M, Paunio T, Arajärvi R, Haukka J, Parker A, Martin R, Levitzky S, Partonen T, Meyer J, Lönnqvist J, Peltonen L, Ekelund J.

Hum Mol Genet. 2003 Dec 1;12(23):3151-9. Epub 2003 Oct 7.

PMID:
14532331
5.

Evidence for association between Disrupted-in-Schizophrenia 1 (DISC1) gene polymorphisms and autism in Chinese Han population: a family-based association study.

Zheng F, Wang L, Jia M, Yue W, Ruan Y, Lu T, Liu J, Li J, Zhang D.

Behav Brain Funct. 2011 May 15;7:14. doi: 10.1186/1744-9081-7-14.

6.

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.

Palo OM, Antila M, Silander K, Hennah W, Kilpinen H, Soronen P, Tuulio-Henriksson A, Kieseppä T, Partonen T, Lönnqvist J, Peltonen L, Paunio T.

Hum Mol Genet. 2007 Oct 15;16(20):2517-28. Epub 2007 Aug 2.

PMID:
17673452
7.

Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory.

Cannon TD, Hennah W, van Erp TG, Thompson PM, Lonnqvist J, Huttunen M, Gasperoni T, Tuulio-Henriksson A, Pirkola T, Toga AW, Kaprio J, Mazziotta J, Peltonen L.

Arch Gen Psychiatry. 2005 Nov;62(11):1205-13.

PMID:
16275808
8.

Association of DISC1 with autism and Asperger syndrome.

Kilpinen H, Ylisaukko-Oja T, Hennah W, Palo OM, Varilo T, Vanhala R, Nieminen-von Wendt T, von Wendt L, Paunio T, Peltonen L.

Mol Psychiatry. 2008 Feb;13(2):187-96. Epub 2007 Jun 19.

PMID:
17579608
9.

A haplotype within the DISC1 gene is associated with visual memory functions in families with a high density of schizophrenia.

Hennah W, Tuulio-Henriksson A, Paunio T, Ekelund J, Varilo T, Partonen T, Cannon TD, Lönnqvist J, Peltonen L.

Mol Psychiatry. 2005 Dec;10(12):1097-103.

PMID:
16103888
10.

Evidence of statistical epistasis between DISC1, CIT and NDEL1 impacting risk for schizophrenia: biological validation with functional neuroimaging.

Nicodemus KK, Callicott JH, Higier RG, Luna A, Nixon DC, Lipska BK, Vakkalanka R, Giegling I, Rujescu D, St Clair D, Muglia P, Shugart YY, Weinberger DR.

Hum Genet. 2010 Apr;127(4):441-52. doi: 10.1007/s00439-009-0782-y. Erratum in: Hum Genet. 2010 Apr;127(4):453-4.

PMID:
20084519
11.

A single nucleotide polymorphism fine mapping study of chromosome 1q42.1 reveals the vulnerability genes for schizophrenia, GNPAT and DISC1: Association with impairment of sustained attention.

Liu YL, Fann CS, Liu CM, Chen WJ, Wu JY, Hung SI, Chen CH, Jou YS, Liu SK, Hwang TJ, Hsieh MH, Ouyang WC, Chan HY, Chen JJ, Yang WC, Lin CY, Lee SF, Hwu HG.

Biol Psychiatry. 2006 Sep 15;60(6):554-62.

PMID:
16997000
12.

Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.

Millar JK, Mackie S, Clapcote SJ, Murdoch H, Pickard BS, Christie S, Muir WJ, Blackwood DH, Roder JC, Houslay MD, Porteous DJ.

J Physiol. 2007 Oct 15;584(Pt 2):401-5. Epub 2007 Sep 6. Review.

13.

An interaction between NDE1 and high birth weight increases schizophrenia susceptibility.

Wegelius A, Pankakoski M, Tomppo L, Lehto U, Lönnqvist J, Suvisaari J, Paunio T, Hennah W.

Psychiatry Res. 2015 Dec 15;230(2):194-9. doi: 10.1016/j.psychres.2015.08.038. Epub 2015 Sep 1.

14.

Association of variants in DISC1 with psychosis-related traits in a large population cohort.

Tomppo L, Hennah W, Miettunen J, Järvelin MR, Veijola J, Ripatti S, Lahermo P, Lichtermann D, Peltonen L, Ekelund J.

Arch Gen Psychiatry. 2009 Feb;66(2):134-41. doi: 10.1001/archgenpsychiatry.2008.524.

15.

Association studies and gene expression analyses of the DISC1-interacting molecules, pericentrin 2 (PCNT2) and DISC1-binding zinc finger protein (DBZ), with schizophrenia and with bipolar disorder.

Anitha A, Nakamura K, Yamada K, Iwayama Y, Toyota T, Takei N, Iwata Y, Suzuki K, Sekine Y, Matsuzaki H, Kawai M, Thanseem I, Miyoshi K, Katayama T, Matsuzaki S, Baba K, Honda A, Hattori T, Shimizu S, Kumamoto N, Kikuchi M, Tohyama M, Yoshikawa T, Mori N.

Am J Med Genet B Neuropsychiatr Genet. 2009 Oct 5;150B(7):967-76. doi: 10.1002/ajmg.b.30926.

PMID:
19191256
16.

DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder.

Hennah W, Thomson P, McQuillin A, Bass N, Loukola A, Anjorin A, Blackwood D, Curtis D, Deary IJ, Harris SE, Isometsä ET, Lawrence J, Lönnqvist J, Muir W, Palotie A, Partonen T, Paunio T, Pylkkö E, Robinson M, Soronen P, Suominen K, Suvisaari J, Thirumalai S, St Clair D, Gurling H, Peltonen L, Porteous D.

Mol Psychiatry. 2009 Sep;14(9):865-73. doi: 10.1038/mp.2008.22. Epub 2008 Mar 4.

PMID:
18317464
17.

The DISC locus in psychiatric illness.

Chubb JE, Bradshaw NJ, Soares DC, Porteous DJ, Millar JK.

Mol Psychiatry. 2008 Jan;13(1):36-64. Epub 2007 Oct 2. Review.

PMID:
17912248
18.

Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

Hodgkinson CA, Goldman D, Jaeger J, Persaud S, Kane JM, Lipsky RH, Malhotra AK.

Am J Hum Genet. 2004 Nov;75(5):862-72. Epub 2004 Sep 22.

19.

Disrupted in schizophrenia 1 genotype and positive symptoms in schizophrenia.

DeRosse P, Hodgkinson CA, Lencz T, Burdick KE, Kane JM, Goldman D, Malhotra AK.

Biol Psychiatry. 2007 May 15;61(10):1208-10. Epub 2006 Oct 19.

PMID:
17054920
20.

Association between a disrupted-in-schizophrenia 1 (DISC1) single nucleotide polymorphism and schizophrenia in a combined Scandinavian case-control sample.

Saetre P, Agartz I, De Franciscis A, Lundmark P, Djurovic S, Kähler A, Andreassen OA, Jakobsen KD, Rasmussen HB, Werge T, Hall H, Terenius L, Jönsson EG.

Schizophr Res. 2008 Dec;106(2-3):237-41. doi: 10.1016/j.schres.2008.08.024. Epub 2008 Sep 24.

PMID:
18818052

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