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Items: 1 to 20 of 134

1.

Leptin exerts an anti-apoptotic effect on human dendritic cells via the PI3K-Akt signaling pathway.

Mattioli B, Giordani L, Quaranta MG, Viora M.

FEBS Lett. 2009 Apr 2;583(7):1102-6. doi: 10.1016/j.febslet.2009.02.029. Epub 2009 Feb 28.

2.

Leptin promotes differentiation and survival of human dendritic cells and licenses them for Th1 priming.

Mattioli B, Straface E, Quaranta MG, Giordani L, Viora M.

J Immunol. 2005 Jun 1;174(11):6820-8. Erratum in: J Immunol. 2005 Sep 1;175(5):3446.

3.

Catalpol inhibits apoptosis in hydrogen peroxide-induced endothelium by activating the PI3K/Akt signaling pathway and modulating expression of Bcl-2 and Bax.

Hu L, Sun Y, Hu J.

Eur J Pharmacol. 2010 Feb 25;628(1-3):155-63. doi: 10.1016/j.ejphar.2009.11.046. Epub 2009 Dec 3.

PMID:
19962976
4.

Human CD34-derived myeloid dendritic cell development requires intact phosphatidylinositol 3-kinase-protein kinase B-mammalian target of rapamycin signaling.

van de Laar L, Buitenhuis M, Wensveen FM, Janssen HL, Coffer PJ, Woltman AM.

J Immunol. 2010 Jun 15;184(12):6600-11. doi: 10.4049/jimmunol.0903089. Epub 2010 May 19.

5.
6.

Leptin induces IL-8 expression via leptin receptor, IRS-1, PI3K, Akt cascade and promotion of NF-kappaB/p300 binding in human synovial fibroblasts.

Tong KM, Shieh DC, Chen CP, Tzeng CY, Wang SP, Huang KC, Chiu YC, Fong YC, Tang CH.

Cell Signal. 2008 Aug;20(8):1478-88. doi: 10.1016/j.cellsig.2008.04.003. Epub 2008 Apr 15.

PMID:
18501560
7.

Leptin reduces gentamicin-induced apoptosis in rat renal tubular cells via the PI3K-Akt signaling pathway.

Chen YC, Chen CH, Hsu YH, Chen TH, Sue YM, Cheng CY, Chen TW.

Eur J Pharmacol. 2011 May 11;658(2-3):213-8. doi: 10.1016/j.ejphar.2011.02.025. Epub 2011 Mar 1.

PMID:
21371463
9.

Leptin induces CD40 expression through the activation of Akt in murine dendritic cells.

Lam QL, Zheng BJ, Jin DY, Cao X, Lu L.

J Biol Chem. 2007 Sep 21;282(38):27587-97. Epub 2007 Jul 27.

10.

15-HETE protects rat pulmonary arterial smooth muscle cells from apoptosis via the PI3K/Akt pathway.

Wang S, Wang Y, Jiang J, Wang R, Li L, Qiu Z, Wu H, Zhu D.

Prostaglandins Other Lipid Mediat. 2010 Feb;91(1-2):51-60. doi: 10.1016/j.prostaglandins.2009.12.007. Epub 2010 Jan 8.

PMID:
20060487
11.

Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL.

Zhande R, Karsan A.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2467-74. Epub 2007 Jan 19.

12.

Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death.

Kajiya M, Shiba H, Fujita T, Takeda K, Uchida Y, Kawaguchi H, Kitagawa M, Takata T, Kurihara H.

J Cell Physiol. 2009 Dec;221(3):696-706. doi: 10.1002/jcp.21909.

PMID:
19711359
13.

Cutting edge: Autocrine TGF-beta sustains default tolerogenesis by IDO-competent dendritic cells.

Belladonna ML, Volpi C, Bianchi R, Vacca C, Orabona C, Pallotta MT, Boon L, Gizzi S, Fioretti MC, Grohmann U, Puccetti P.

J Immunol. 2008 Oct 15;181(8):5194-8.

14.

Leptin stimulates alpha1(I) collagen expression in human hepatic stellate cells via the phosphatidylinositol 3-kinase/Akt signalling pathway.

Niu L, Wang X, Li J, Huang Y, Yang Z, Chen F, Ni H, Jin Y, Lu X, Cao Q.

Liver Int. 2007 Nov;27(9):1265-72.

PMID:
17919239
15.

Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt.

Liu B, Shi ZL, Feng J, Tao HM.

Cell Biol Int. 2008 May;32(5):494-501. Epub 2007 Nov 5.

PMID:
18078766
16.

Magnolol induces apoptosis via inhibiting the EGFR/PI3K/Akt signaling pathway in human prostate cancer cells.

Lee DH, Szczepanski MJ, Lee YJ.

J Cell Biochem. 2009 Apr 15;106(6):1113-22. doi: 10.1002/jcb.22098.

PMID:
19229860
17.

Distinct roles for the NF-kappaB1 and c-Rel transcription factors in the differentiation and survival of plasmacytoid and conventional dendritic cells activated by TLR-9 signals.

O'Keeffe M, Grumont RJ, Hochrein H, Fuchsberger M, Gugasyan R, Vremec D, Shortman K, Gerondakis S.

Blood. 2005 Nov 15;106(10):3457-64. Epub 2005 Jul 21.

18.

Parathyroid hormone-related protein induces cell survival in human renal cell carcinoma through the PI3K Akt pathway: evidence for a critical role for integrin-linked kinase and nuclear factor kappa B.

Agouni A, Sourbier C, Danilin S, Rothhut S, Lindner V, Jacqmin D, Helwig JJ, Lang H, Massfelder T.

Carcinogenesis. 2007 Sep;28(9):1893-901. Epub 2007 Apr 29.

PMID:
17468516
19.

Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway.

Kui L, Weiwei Z, Ling L, Daikun H, Guoming Z, Linuo Z, Renming H.

Regul Pept. 2009 Jun 5;155(1-3):62-9. doi: 10.1016/j.regpep.2009.03.003. Epub 2009 Mar 14.

PMID:
19289146
20.

Phosphatidylinositol-3-phosphate kinase pathway activation protects leukemic large granular lymphocytes from undergoing homeostatic apoptosis.

Schade AE, Powers JJ, Wlodarski MW, Maciejewski JP.

Blood. 2006 Jun 15;107(12):4834-40. Epub 2006 Feb 16.

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