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Items: 1 to 20 of 120

1.

Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathway.

Patterson VL, Damrau C, Paudyal A, Reeve B, Grimes DT, Stewart ME, Williams DJ, Siggers P, Greenfield A, Murdoch JN.

Hum Mol Genet. 2009 May 15;18(10):1719-39. doi: 10.1093/hmg/ddp075. Epub 2009 Feb 17.

2.

Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling.

Norman RX, Ko HW, Huang V, Eun CM, Abler LL, Zhang Z, Sun X, Eggenschwiler JT.

Hum Mol Genet. 2009 May 15;18(10):1740-54. doi: 10.1093/hmg/ddp113. Epub 2009 Mar 12.

3.

Tulp3 is a critical repressor of mouse hedgehog signaling.

Cameron DA, Pennimpede T, Petkovich M.

Dev Dyn. 2009 May;238(5):1140-9. doi: 10.1002/dvdy.21926.

4.

G-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.

Hwang SH, Mukhopadhyay S.

Birth Defects Res A Clin Mol Teratol. 2015 Jan;103(1):12-9. doi: 10.1002/bdra.23267. Epub 2014 Jun 11.

PMID:
24917297
5.

Cadherin-7 enhances Sonic Hedgehog signalling by preventing Gli3 repressor formation during neural tube patterning.

Kawano R, Ohta K, Lupo G.

Open Biol. 2017 Dec;7(12). pii: 170225. doi: 10.1098/rsob.170225.

6.

Preaxial polydactyly caused by Gli3 haploinsufficiency is rescued by Zic3 loss of function in mice.

Quinn ME, Haaning A, Ware SM.

Hum Mol Genet. 2012 Apr 15;21(8):1888-96. doi: 10.1093/hmg/dds002. Epub 2012 Jan 10.

7.

Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling.

Christopher KJ, Wang B, Kong Y, Weatherbee SD.

Dev Biol. 2012 Aug 15;368(2):382-92. doi: 10.1016/j.ydbio.2012.06.008. Epub 2012 Jun 12.

8.

Ventral neural patterning in the absence of a Shh activity gradient from the floorplate.

Iulianella A, Sakai D, Kurosaka H, Trainor PA.

Dev Dyn. 2018 Jan;247(1):170-184. doi: 10.1002/dvdy.24590. Epub 2017 Oct 17.

9.

Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.

Wong RL, Wlodarczyk BJ, Min KS, Scott ML, Kartiko S, Yu W, Merriweather MY, Vogel P, Zambrowicz BP, Finnell RH.

Hum Mol Genet. 2008 Feb 15;17(4):587-601. Epub 2007 Nov 13.

PMID:
18003640
10.

Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway.

Eggenschwiler JT, Espinoza E, Anderson KV.

Nature. 2001 Jul 12;412(6843):194-8.

PMID:
11449277
11.

Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.

Tuson M, He M, Anderson KV.

Development. 2011 Nov;138(22):4921-30. doi: 10.1242/dev.070805. Epub 2011 Oct 17.

12.

Spop regulates Gli3 activity and Shh signaling in dorsoventral patterning of the mouse spinal cord.

Cai H, Liu A.

Dev Biol. 2017 Dec 1;432(1):72-85. doi: 10.1016/j.ydbio.2017.04.002. Epub 2017 Apr 12.

13.

Wnt won the war: antagonistic role of Wnt over Shh controls dorso-ventral patterning of the vertebrate neural tube.

Ulloa F, Martí E.

Dev Dyn. 2010 Jan;239(1):69-76. doi: 10.1002/dvdy.22058. Review.

14.

Differential requirement of SUFU in tissue development discovered in a hypomorphic mouse model.

Hoelzl MA, Heby-Henricson K, Gerling M, Dias JM, Kuiper RV, Trünkle C, Bergström Å, Ericson J, Toftgård R, Teglund S.

Dev Biol. 2017 Sep 1;429(1):132-146. doi: 10.1016/j.ydbio.2017.06.037. Epub 2017 Jul 5.

15.

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components.

Qin J, Lin Y, Norman RX, Ko HW, Eggenschwiler JT.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1456-61. doi: 10.1073/pnas.1011410108. Epub 2011 Jan 5.

16.

Direct functional consequences of ZRS enhancer mutation combine with secondary long range SHH signalling effects to cause preaxial polydactyly.

Johnson EJ, Neely DM, Dunn IC, Davey MG.

Dev Biol. 2014 Aug 15;392(2):209-20. doi: 10.1016/j.ydbio.2014.05.025. Epub 2014 Jun 5.

17.

Wnt canonical pathway restricts graded Shh/Gli patterning activity through the regulation of Gli3 expression.

Alvarez-Medina R, Cayuso J, Okubo T, Takada S, Martí E.

Development. 2008 Jan;135(2):237-47. Epub 2007 Dec 5.

18.

GATA6 is a crucial regulator of Shh in the limb bud.

Kozhemyakina E, Ionescu A, Lassar AB.

PLoS Genet. 2014 Jan;10(1):e1004072. doi: 10.1371/journal.pgen.1004072. Epub 2014 Jan 9.

19.

Mouse Gli1 mutants are viable but have defects in SHH signaling in combination with a Gli2 mutation.

Park HL, Bai C, Platt KA, Matise MP, Beeghly A, Hui CC, Nakashima M, Joyner AL.

Development. 2000 Apr;127(8):1593-605.

20.

Neogenin regulates Sonic Hedgehog pathway activity during digit patterning.

Hong M, Schachter KA, Jiang G, Krauss RS.

Dev Dyn. 2012 Mar;241(3):627-37. doi: 10.1002/dvdy.23745.

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