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Items: 1 to 20 of 91

1.

Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression.

Yoo BK, Emdad L, Su ZZ, Villanueva A, Chiang DY, Mukhopadhyay ND, Mills AS, Waxman S, Fisher RA, Llovet JM, Fisher PB, Sarkar D.

J Clin Invest. 2009 Mar;119(3):465-77. doi: 10.1172/JCI36460. Epub 2009 Feb 16.

2.

Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.

Srivastava J, Siddiq A, Emdad L, Santhekadur PK, Chen D, Gredler R, Shen XN, Robertson CL, Dumur CI, Hylemon PB, Mukhopadhyay ND, Bhere D, Shah K, Ahmad R, Giashuddin S, Stafflinger J, Subler MA, Windle JJ, Fisher PB, Sarkar D.

Hepatology. 2012 Nov;56(5):1782-91. doi: 10.1002/hep.25868.

3.

Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma.

Yoo BK, Emdad L, Gredler R, Fuller C, Dumur CI, Jones KH, Jackson-Cook C, Su ZZ, Chen D, Saxena UH, Hansen U, Fisher PB, Sarkar D.

Proc Natl Acad Sci U S A. 2010 May 4;107(18):8357-62. doi: 10.1073/pnas.1000374107. Epub 2010 Apr 19.

4.

Insulin-like growth factor-binding protein-7 functions as a potential tumor suppressor in hepatocellular carcinoma.

Chen D, Yoo BK, Santhekadur PK, Gredler R, Bhutia SK, Das SK, Fuller C, Su ZZ, Fisher PB, Sarkar D.

Clin Cancer Res. 2011 Nov 1;17(21):6693-701. doi: 10.1158/1078-0432.CCR-10-2774. Epub 2011 Sep 9.

5.

Astrocyte Elevated Gene-1 (AEG-1) Contributes to Non-thyroidal Illness Syndrome (NTIS) Associated with Hepatocellular Carcinoma (HCC).

Srivastava J, Robertson CL, Gredler R, Siddiq A, Rajasekaran D, Akiel MA, Emdad L, Mas V, Mukhopadhyay ND, Fisher PB, Sarkar D.

J Biol Chem. 2015 Jun 19;290(25):15549-58. doi: 10.1074/jbc.M115.649707. Epub 2015 May 5.

6.

Overexpression of astrocyte-elevated gene-1 is associated with ovarian cancer development and progression.

Zhou B, Yang J, Shu B, Liu K, Xue L, Su N, Liu J, Xi T.

Mol Med Rep. 2015 Apr;11(4):2981-90. doi: 10.3892/mmr.2014.3056. Epub 2014 Dec 5.

PMID:
25483832
7.

Myocyte enhancer factor 2C regulation of hepatocellular carcinoma via vascular endothelial growth factor and Wnt/β-catenin signaling.

Bai XL, Zhang Q, Ye LY, Liang F, Sun X, Chen Y, Hu QD, Fu QH, Su W, Chen Z, Zhuang ZP, Liang TB.

Oncogene. 2015 Jul 30;34(31):4089-97. doi: 10.1038/onc.2014.337. Epub 2014 Oct 20.

PMID:
25328135
8.

The emerging role of astrocyte-elevated gene-1 in hepatocellular carcinoma (Review).

Zhu HD, Liao JZ, He XX, Li PY.

Oncol Rep. 2015 Aug;34(2):539-46. doi: 10.3892/or.2015.4024. Epub 2015 May 29. Review.

PMID:
26035424
9.

Pivotal role of mTOR signaling in hepatocellular carcinoma.

Villanueva A, Chiang DY, Newell P, Peix J, Thung S, Alsinet C, Tovar V, Roayaie S, Minguez B, Sole M, Battiston C, Van Laarhoven S, Fiel MI, Di Feo A, Hoshida Y, Yea S, Toffanin S, Ramos A, Martignetti JA, Mazzaferro V, Bruix J, Waxman S, Schwartz M, Meyerson M, Friedman SL, Llovet JM.

Gastroenterology. 2008 Dec;135(6):1972-83, 1983.e1-11. doi: 10.1053/j.gastro.2008.08.008. Epub 2008 Aug 20.

10.

Tetraspanin 8 mediates AEG-1-induced invasion and metastasis in hepatocellular carcinoma cells.

Akiel MA, Santhekadur PK, Mendoza RG, Siddiq A, Fisher PB, Sarkar D.

FEBS Lett. 2016 Aug;590(16):2700-8. doi: 10.1002/1873-3468.12268. Epub 2016 Jul 21.

PMID:
27339400
11.

MicroRNA-375 targets AEG-1 in hepatocellular carcinoma and suppresses liver cancer cell growth in vitro and in vivo.

He XX, Chang Y, Meng FY, Wang MY, Xie QH, Tang F, Li PY, Song YH, Lin JS.

Oncogene. 2012 Jul 12;31(28):3357-69. doi: 10.1038/onc.2011.500. Epub 2011 Nov 7.

PMID:
22056881
12.

Tiam1 is associated with hepatocellular carcinoma metastasis.

Huang J, Ye X, Guan J, Chen B, Li Q, Zheng X, Liu L, Wang S, Ding Y, Ding Y, Chen L.

Int J Cancer. 2013 Jan 1;132(1):90-100. doi: 10.1002/ijc.27627. Epub 2012 May 29. Erratum in: Int J Cancer. 2015 Oct 15;137(8):E14. Int J Cancer. 2015 Oct 15;137(8):E16.

13.

EpCAM-positive hepatocellular carcinoma cells are tumor-initiating cells with stem/progenitor cell features.

Yamashita T, Ji J, Budhu A, Forgues M, Yang W, Wang HY, Jia H, Ye Q, Qin LX, Wauthier E, Reid LM, Minato H, Honda M, Kaneko S, Tang ZY, Wang XW.

Gastroenterology. 2009 Mar;136(3):1012-24. doi: 10.1053/j.gastro.2008.12.004. Epub 2008 Dec 6.

14.

NF-κB signaling relieves negative regulation by miR-194 in hepatocellular carcinoma by suppressing the transcription factor HNF-1α.

Bao C, Li Y, Huan L, Zhang Y, Zhao F, Wang Q, Liang L, Ding J, Liu L, Chen T, Li J, Yao M, Huang S, He X.

Sci Signal. 2015 Jul 28;8(387):ra75. doi: 10.1126/scisignal.aaa8441.

PMID:
26221053
15.

SOX1 functions as a tumor suppressor by antagonizing the WNT/β-catenin signaling pathway in hepatocellular carcinoma.

Tsao CM, Yan MD, Shih YL, Yu PN, Kuo CC, Lin WC, Li HJ, Lin YW.

Hepatology. 2012 Dec;56(6):2277-87. doi: 10.1002/hep.25933.

PMID:
22767186
16.

MiR-214 targets β-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.

Xia H, Ooi LL, Hui KM.

PLoS One. 2012;7(9):e44206. doi: 10.1371/journal.pone.0044206. Epub 2012 Sep 4. Erratum in: PLoS One. 2012;7(9). doi:10.1371/annotation/1be2a62e-45a1-4c13-9a8d-f265005a21e0.

17.

USP14 activation promotes tumor progression in hepatocellular carcinoma.

Huang G, Li L, Zhou W.

Oncol Rep. 2015 Dec;34(6):2917-24. doi: 10.3892/or.2015.4296. Epub 2015 Sep 21.

PMID:
26397990
18.

Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo.

Newell P, Toffanin S, Villanueva A, Chiang DY, Minguez B, Cabellos L, Savic R, Hoshida Y, Lim KH, Melgar-Lesmes P, Yea S, Peix J, Deniz K, Fiel MI, Thung S, Alsinet C, Tovar V, Mazzaferro V, Bruix J, Roayaie S, Schwartz M, Friedman SL, Llovet JM.

J Hepatol. 2009 Oct;51(4):725-33. doi: 10.1016/j.jhep.2009.03.028. Epub 2009 Jun 12.

19.

miR-139 regulates the proliferation and invasion of hepatocellular carcinoma through the WNT/TCF-4 pathway.

Gu W, Li X, Wang J.

Oncol Rep. 2014 Jan;31(1):397-404. doi: 10.3892/or.2013.2831. Epub 2013 Nov 1.

PMID:
24190507
20.

MiR-148b suppresses cell proliferation and invasion in hepatocellular carcinoma by targeting WNT1/β-catenin pathway.

Zhang JG, Shi Y, Hong DF, Song M, Huang D, Wang CY, Zhao G.

Sci Rep. 2015 Jan 28;5:8087. doi: 10.1038/srep08087.

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