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Items: 1 to 20 of 96

1.

Cartilage proteoglycan aggrecan epitopes induce proinflammatory autoreactive T-cell responses in rheumatoid arthritis and osteoarthritis.

de Jong H, Berlo SE, Hombrink P, Otten HG, van Eden W, Lafeber FP, Heurkens AH, Bijlsma JW, Glant TT, Prakken BJ.

Ann Rheum Dis. 2010 Jan;69(1):255-62. doi: 10.1136/ard.2008.103978.

PMID:
19213744
2.

Immune Recognition of Citrullinated Proteoglycan Aggrecan Epitopes in Mice with Proteoglycan-Induced Arthritis and in Patients with Rheumatoid Arthritis.

Markovics A, Ocskó T, Katz RS, Buzás EI, Glant TT, Mikecz K.

PLoS One. 2016 Jul 28;11(7):e0160284. doi: 10.1371/journal.pone.0160284. eCollection 2016.

3.

Predominant cellular immune response to the cartilage autoantigenic G1 aggrecan in ankylosing spondylitis and rheumatoid arthritis.

Zou J, Zhang Y, Thiel A, Rudwaleit M, Shi SL, Radbruch A, Poole R, Braun J, Sieper J.

Rheumatology (Oxford). 2003 Jul;42(7):846-55. Epub 2003 Feb 28.

PMID:
12730543
4.

The role of citrullination of an immunodominant proteoglycan (PG) aggrecan T cell epitope in BALB/c mice with PG-induced arthritis.

Misják P, Bősze S, Horváti K, Pásztói M, Pálóczi K, Holub MC, Szakács F, Aradi B, György B, Szabó TG, Nagy G, Glant TT, Mikecz K, Falus A, Buzás EI.

Immunol Lett. 2013 Apr;152(1):25-31. doi: 10.1016/j.imlet.2013.03.005. Epub 2013 Apr 8.

PMID:
23578666
5.
6.

Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan.

Hanyecz A, Bárdos T, Berlo SE, Buzás E, Nesterovitch AB, Mikecz K, Glant TT.

Arthritis Rheum. 2003 Oct;48(10):2959-73.

7.

The influence of MHC class II molecules containing the rheumatoid arthritis shared epitope on the immune response to aggrecan G1 and its peptides.

Brintnell W, Bell DA, Hill JA, Jevnikar AM, Sette A, Sidney J, Doege K, Cairns E.

Scand J Immunol. 2007 May;65(5):444-52.

8.

Selection of self-reactive peptides within human aggrecan by use of a HLA-DRB1*0401 peptide binding motif.

Boots AM, Verheijden GF, Schöningh R, van Staveren CJ, Bos E, Elewaut D, de Keyser F, Veys E, Joosten I, Rijnders AW.

J Autoimmun. 1997 Dec;10(6):569-78.

PMID:
9451596
9.

Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.

Glant TT, Radacs M, Nagyeri G, Olasz K, Laszlo A, Boldizsar F, Hegyi A, Finnegan A, Mikecz K.

Arthritis Rheum. 2011 May;63(5):1312-21. doi: 10.1002/art.30261.

10.

Response of Th17 cells to a citrullinated arthritogenic aggrecan peptide in patients with rheumatoid arthritis.

von Delwig A, Locke J, Robinson JH, Ng WF.

Arthritis Rheum. 2010 Jan;62(1):143-9. doi: 10.1002/art.25064.

11.

Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis.

de Jong H, Lafeber FF, de Jager W, Haverkamp MH, Kuis W, Bijlsma JW, Prakken BJ, Albani S.

Arthritis Rheum. 2009 Jul;60(7):1966-76. doi: 10.1002/art.24656.

12.

Characterization and Localization of Citrullinated Proteoglycan Aggrecan in Human Articular Cartilage.

Glant TT, Ocsko T, Markovics A, Szekanecz Z, Katz RS, Rauch TA, Mikecz K.

PLoS One. 2016 Mar 4;11(3):e0150784. doi: 10.1371/journal.pone.0150784. eCollection 2016.

13.

Cellular immunity to the G1 domain of cartilage proteoglycan aggrecan is enhanced in patients with rheumatoid arthritis but only after removal of keratan sulfate.

Guerassimov A, Zhang Y, Banerjee S, Cartman A, Leroux JY, Rosenberg LC, Esdaile J, Fitzcharles MA, Poole AR.

Arthritis Rheum. 1998 Jun;41(6):1019-25.

PMID:
9627011
14.

Progressive polyarthritis induced in BALB/c mice by aggrecan from normal and osteoarthritic human cartilage.

Glant TT, Cs-Szabó G, Nagase H, Jacobs JJ, Mikecz K.

Arthritis Rheum. 1998 Jun;41(6):1007-18.

PMID:
9627010
15.

Human cartilage aggrecan CS1 region contains cryptic T-cell recognition sites.

Goodacre JA, Middleton S, Lynn S, Ross DA, Pearson J.

Immunology. 1993 Apr;78(4):586-91.

16.

Molecular manipulation with the arthritogenic epitopes of the G1 domain of human cartilage proteoglycan aggrecan.

Murad YM, Szabó Z, Ludányi K, Glant TT.

Clin Exp Immunol. 2005 Nov;142(2):303-11.

17.

Cellular immunity to cartilage aggrecan core protein in patients with rheumatoid arthritis and non-arthritic controls.

Goodstone NJ, Doran MC, Hobbs RN, Butler RC, Dixey JJ, Ashton BA.

Ann Rheum Dis. 1996 Jan;55(1):40-6.

18.

Identification of self-epitopes recognized by T cells in rheumatoid arthritis demonstrates matrix metalloproteinases as a novel T cell target.

ter Steege J, Vianen M, van Bilsen J, Bijlsma J, Lafeber F, Wauben M.

J Rheumatol. 2003 Jun;30(6):1147-56.

PMID:
12784383
19.

T-cell recognition of differentially tolerated epitopes of cartilage proteoglycan aggrecan in arthritis.

Buzás EI, Végvári A, Murad YM, Finnegan A, Mikecz K, Glant TT.

Cell Immunol. 2005 Jun;235(2):98-108. Epub 2005 Sep 23.

PMID:
16185673
20.

Prevention and reversal of cartilage degradation in rheumatoid arthritis by interleukin-10 and interleukin-4.

van Roon JA, van Roy JL, Gmelig-Meyling FH, Lafeber FP, Bijlsma JW.

Arthritis Rheum. 1996 May;39(5):829-35.

PMID:
8639180

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