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Items: 1 to 20 of 97

1.

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2.

Friedman MS, Oyserman SM, Hankenson KD.

J Biol Chem. 2009 May 22;284(21):14117-25. doi: 10.1074/jbc.M808337200. Epub 2009 Feb 12.

2.

Dkk1-induced inhibition of Wnt signaling in osteoblast differentiation is an underlying mechanism of bone loss in multiple myeloma.

Qiang YW, Barlogie B, Rudikoff S, Shaughnessy JD Jr.

Bone. 2008 Apr;42(4):669-80. doi: 10.1016/j.bone.2007.12.006. Epub 2007 Dec 27.

PMID:
18294945
3.

Bortezomib induces osteoblast differentiation via Wnt-independent activation of beta-catenin/TCF signaling.

Qiang YW, Hu B, Chen Y, Zhong Y, Shi B, Barlogie B, Shaughnessy JD Jr.

Blood. 2009 Apr 30;113(18):4319-30. doi: 10.1182/blood-2008-08-174300. Epub 2009 Feb 4.

4.

FHL2 mediates dexamethasone-induced mesenchymal cell differentiation into osteoblasts by activating Wnt/beta-catenin signaling-dependent Runx2 expression.

Hamidouche Z, Haÿ E, Vaudin P, Charbord P, Schüle R, Marie PJ, Fromigué O.

FASEB J. 2008 Nov;22(11):3813-22. doi: 10.1096/fj.08-106302. Epub 2008 Jul 24.

PMID:
18653765
5.

LGR4 acts as a key receptor for R-spondin 2 to promote osteogenesis through Wnt signaling pathway.

Zhu C, Zheng XF, Yang YH, Li B, Wang YR, Jiang SD, Jiang LS.

Cell Signal. 2016 Aug;28(8):989-1000. doi: 10.1016/j.cellsig.2016.04.010. Epub 2016 Apr 29.

PMID:
27140682
6.

Differentiation-inducing factor-1 alters canonical Wnt signaling and suppresses alkaline phosphatase expression in osteoblast-like cell lines.

Matsuzaki E, Takahashi-Yanaga F, Miwa Y, Hirata M, Watanabe Y, Sato N, Morimoto S, Hirofuji T, Maeda K, Sasaguri T.

J Bone Miner Res. 2006 Aug;21(8):1307-16.

7.

Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts.

Zhang R, Oyajobi BO, Harris SE, Chen D, Tsao C, Deng HW, Zhao M.

Bone. 2013 Jan;52(1):145-56. doi: 10.1016/j.bone.2012.09.029. Epub 2012 Sep 29.

8.

R-spondin 2 facilitates differentiation of proliferating chondrocytes into hypertrophic chondrocytes by enhancing Wnt/β-catenin signaling in endochondral ossification.

Takegami Y, Ohkawara B, Ito M, Masuda A, Nakashima H, Ishiguro N, Ohno K.

Biochem Biophys Res Commun. 2016 Apr 22;473(1):255-264. doi: 10.1016/j.bbrc.2016.03.089. Epub 2016 Mar 22.

PMID:
27012200
9.

ATP and UTP stimulate bone morphogenetic protein-2,-4 and -5 gene expression and mineralization by rat primary osteoblasts involving PI3K/AKT pathway.

Ayala-Peña VB, Scolaro LA, Santillán GE.

Exp Cell Res. 2013 Aug 1;319(13):2028-36. doi: 10.1016/j.yexcr.2013.05.006. Epub 2013 May 23.

PMID:
23707969
10.

Postnatal ablation of osteoblast Smad4 enhances proliferative responses to canonical Wnt signaling through interactions with β-catenin.

Salazar VS, Zarkadis N, Huang L, Watkins M, Kading J, Bonar S, Norris J, Mbalaviele G, Civitelli R.

J Cell Sci. 2013 Dec 15;126(Pt 24):5598-609. doi: 10.1242/jcs.132233. Epub 2013 Oct 7.

11.

Lithium chloride attenuates BMP-2 signaling and inhibits osteogenic differentiation through a novel WNT/GSK3- independent mechanism.

Li J, Khavandgar Z, Lin SH, Murshed M.

Bone. 2011 Feb;48(2):321-31. doi: 10.1016/j.bone.2010.09.033. Epub 2010 Oct 12.

PMID:
20932949
12.

Bmp Induces Osteoblast Differentiation through both Smad4 and mTORC1 Signaling.

Karner CM, Lee SY, Long F.

Mol Cell Biol. 2017 Feb 1;37(4). pii: e00253-16. doi: 10.1128/MCB.00253-16. Print 2017 Feb 15.

13.

COMP-Ang1, a chimeric form of Angiopoietin 1, enhances BMP2-induced osteoblast differentiation and bone formation.

Jeong BC, Kim HJ, Bae IH, Lee KN, Lee KY, Oh WM, Kim SH, Kang IC, Lee SE, Koh GY, Kim KK, Koh JT.

Bone. 2010 Feb;46(2):479-86. doi: 10.1016/j.bone.2009.09.019. Epub 2009 Sep 25.

PMID:
19782780
14.

Beta-catenin signaling plays a disparate role in different phases of fracture repair: implications for therapy to improve bone healing.

Chen Y, Whetstone HC, Lin AC, Nadesan P, Wei Q, Poon R, Alman BA.

PLoS Med. 2007 Jul 31;4(7):e249.

15.

Betulinic acid stimulates the differentiation and mineralization of osteoblastic MC3T3-E1 cells: involvement of BMP/Runx2 and beta-catenin signals.

Lo YC, Chang YH, Wei BL, Huang YL, Chiou WF.

J Agric Food Chem. 2010 Jun 9;58(11):6643-9. doi: 10.1021/jf904158k.

PMID:
20443623
16.

R-spondins are newly recognized players in osteoarthritis that regulate Wnt signaling in osteoblasts.

Abed É, Chan TF, Delalandre A, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

Arthritis Rheum. 2011 Dec;63(12):3865-75. doi: 10.1002/art.30625.

17.

N-cadherin interacts with axin and LRP5 to negatively regulate Wnt/beta-catenin signaling, osteoblast function, and bone formation.

Haÿ E, Laplantine E, Geoffroy V, Frain M, Kohler T, Müller R, Marie PJ.

Mol Cell Biol. 2009 Feb;29(4):953-64. doi: 10.1128/MCB.00349-08. Epub 2008 Dec 15.

18.

Stretch-induced inhibition of Wnt/beta-catenin signaling in mineralizing osteoblasts.

Jansen JH, Eijken M, Jahr H, Chiba H, Verhaar JA, van Leeuwen JP, Weinans H.

J Orthop Res. 2010 Mar;28(3):390-6. doi: 10.1002/jor.20991.

19.

Osthole stimulates osteoblast differentiation and bone formation by activation of beta-catenin-BMP signaling.

Tang DZ, Hou W, Zhou Q, Zhang M, Holz J, Sheu TJ, Li TF, Cheng SD, Shi Q, Harris SE, Chen D, Wang YJ.

J Bone Miner Res. 2010 Jun;25(6):1234-45. doi: 10.1002/jbmr.21.

20.

Conserved regulatory motifs in osteogenic gene promoters integrate cooperative effects of canonical Wnt and BMP pathways.

Rodríguez-Carballo E, Ulsamer A, Susperregui AR, Manzanares-Céspedes C, Sánchez-García E, Bartrons R, Rosa JL, Ventura F.

J Bone Miner Res. 2011 Apr;26(4):718-29. doi: 10.1002/jbmr.260.

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