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Items: 1 to 20 of 1838

1.

c-Met confers protection against chronic liver tissue damage and fibrosis progression after bile duct ligation in mice.

Giebeler A, Boekschoten MV, Klein C, Borowiak M, Birchmeier C, Gassler N, Wasmuth HE, Müller M, Trautwein C, Streetz KL.

Gastroenterology. 2009 Jul;137(1):297-308, 308.e1-4. doi: 10.1053/j.gastro.2009.01.068. Epub 2009 Feb 5.

PMID:
19208365
2.

Antinecrotic and antiapoptotic effects of hepatocyte growth factor on cholestatic hepatitis in a mouse model of bile-obstructive diseases.

Li Z, Mizuno S, Nakamura T.

Am J Physiol Gastrointest Liver Physiol. 2007 Feb;292(2):G639-46. Epub 2006 Oct 26.

3.

Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

Canbay A, Higuchi H, Bronk SF, Taniai M, Sebo TJ, Gores GJ.

Gastroenterology. 2002 Oct;123(4):1323-30.

PMID:
12360492
4.

Transcriptional profiling after bile duct ligation identifies PAI-1 as a contributor to cholestatic injury in mice.

Wang H, Vohra BP, Zhang Y, Heuckeroth RO.

Hepatology. 2005 Nov;42(5):1099-108.

PMID:
16250054
6.

Relationship between the proliferative capability of hepatocytes and the intrahepatic expression of hepatocyte growth factor and c-Met in the course of cirrhosis development in rats.

Inoue H, Yokoyama F, Kita Y, Yoshiji H, Tsujimoto T, Deguchi A, Nakai S, Morishita A, Uchida N, Masaki T, Watanabe S, Kuriyama S.

Int J Mol Med. 2006 May;17(5):857-64.

PMID:
16596271
7.

Hepatocyte specific deletion of c-Met leads to the development of severe non-alcoholic steatohepatitis in mice.

Kroy DC, Schumacher F, Ramadori P, Hatting M, Bergheim I, Gassler N, Boekschoten MV, Müller M, Streetz KL, Trautwein C.

J Hepatol. 2014 Oct;61(4):883-90. doi: 10.1016/j.jhep.2014.05.019. Epub 2014 May 15.

PMID:
24845607
8.

Hepatocyte-specific Smad7 expression attenuates TGF-beta-mediated fibrogenesis and protects against liver damage.

Dooley S, Hamzavi J, Ciuclan L, Godoy P, Ilkavets I, Ehnert S, Ueberham E, Gebhardt R, Kanzler S, Geier A, Breitkopf K, Weng H, Mertens PR.

Gastroenterology. 2008 Aug;135(2):642-59. doi: 10.1053/j.gastro.2008.04.038. Epub 2008 May 15.

9.

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury.

Tamaki N, Hatano E, Taura K, Tada M, Kodama Y, Nitta T, Iwaisako K, Seo S, Nakajima A, Ikai I, Uemoto S.

Am J Physiol Gastrointest Liver Physiol. 2008 Feb;294(2):G498-505. doi: 10.1152/ajpgi.00482.2007. Epub 2008 Jan 3.

10.

Lack of hepatic c-Met and gp130 expression is associated with an impaired antibacterial response and higher lethality after bile duct ligation.

Giebeler A, Brandenburg LO, Kaldenbach M, Erschfeld S, Wasmuth H, Wruck C, Trautwein C, Streetz KL.

Lab Invest. 2012 Dec;92(12):1726-37. doi: 10.1038/labinvest.2012.122. Epub 2012 Sep 17.

11.

Acute obstructive cholangiopathy in interleukin-6 deficient mice: compensation by leukemia inhibitory factor (LIF) suggests importance of gp-130 signaling in the ductular reaction.

Liu Z, Sakamoto T, Yokomuro S, Ezure T, Subbotin V, Murase N, Contrucci S, Demetris AJ.

Liver. 2000 Apr;20(2):114-24.

PMID:
10847479
12.

Involvement of STAT3-regulated hepatic soluble factors in attenuation of stellate cell activity and liver fibrogenesis in mice.

Shigekawa M, Takehara T, Kodama T, Hikita H, Shimizu S, Li W, Miyagi T, Hosui A, Tatsumi T, Ishida H, Kanto T, Hiramatsu N, Hayashi N.

Biochem Biophys Res Commun. 2011 Mar 25;406(4):614-20. doi: 10.1016/j.bbrc.2011.02.105. Epub 2011 Feb 26.

PMID:
21356197
13.

Chronic bile duct obstruction induces changes in plasma and hepatic levels of cytokines and nitric oxide in the rat.

Fernández-Martínez E, Pérez-Alvarez V, Tsutsumi V, Shibayama M, Muriel P.

Exp Toxicol Pathol. 2006 Aug;58(1):49-58. Epub 2006 Apr 17.

PMID:
16617007
14.

The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse.

Canbay A, Feldstein A, Baskin-Bey E, Bronk SF, Gores GJ.

J Pharmacol Exp Ther. 2004 Mar;308(3):1191-6. Epub 2003 Nov 14.

15.

c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model.

Boost KA, Kim HJ, Engl T, Oppermann E, Jonas D, Oertl A, Blaheta RA.

Int J Mol Med. 2006 Mar;17(3):475-82.

PMID:
16465395
16.

Platelet-derived growth factor isoform expression in carbon tetrachloride-induced chronic liver injury.

Borkham-Kamphorst E, Kovalenko E, van Roeyen CR, Gassler N, Bomble M, Ostendorf T, Floege J, Gressner AM, Weiskirchen R.

Lab Invest. 2008 Oct;88(10):1090-100. doi: 10.1038/labinvest.2008.71. Epub 2008 Jul 28.

17.

Adenoviral CCN3/NOV gene transfer fails to mitigate liver fibrosis in an experimental bile duct ligation model because of hepatocyte apoptosis.

Borkham-Kamphorst E, Huss S, Van de Leur E, Haas U, Weiskirchen R.

Liver Int. 2012 Oct;32(9):1342-53. doi: 10.1111/j.1478-3231.2012.02837.x. Epub 2012 Jun 15.

PMID:
22698069
18.

Potent antioxidant role of pirfenidone in experimental cirrhosis.

Salazar-Montes A, Ruiz-Corro L, López-Reyes A, Castrejón-Gómez E, Armendáriz-Borunda J.

Eur J Pharmacol. 2008 Oct 24;595(1-3):69-77. doi: 10.1016/j.ejphar.2008.06.110. Epub 2008 Jul 9.

PMID:
18652820
19.

Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury.

Beraza N, Lüdde T, Assmus U, Roskams T, Vander Borght S, Trautwein C.

Gastroenterology. 2007 Jun;132(7):2504-17. Epub 2007 Apr 6.

PMID:
17570222
20.

Hepatocyte growth factor twenty years on: Much more than a growth factor.

Nakamura T, Sakai K, Nakamura T, Matsumoto K.

J Gastroenterol Hepatol. 2011 Jan;26 Suppl 1:188-202. doi: 10.1111/j.1440-1746.2010.06549.x. Review.

PMID:
21199531

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