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Items: 1 to 20 of 106

1.

MinK-dependent internalization of the IKs potassium channel.

Xu X, Kanda VA, Choi E, Panaghie G, Roepke TK, Gaeta SA, Christini DJ, Lerner DJ, Abbott GW.

Cardiovasc Res. 2009 Jun 1;82(3):430-8. doi: 10.1093/cvr/cvp047. Epub 2009 Feb 7.

2.

Protein kinase C downregulates I(Ks) by stimulating KCNQ1-KCNE1 potassium channel endocytosis.

Kanda VA, Purtell K, Abbott GW.

Heart Rhythm. 2011 Oct;8(10):1641-7. doi: 10.1016/j.hrthm.2011.04.034. Epub 2011 May 10.

3.

Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2.

Jiang M, Xu X, Wang Y, Toyoda F, Liu XS, Zhang M, Robinson RB, Tseng GN.

J Biol Chem. 2009 Jun 12;284(24):16452-62. doi: 10.1074/jbc.M808262200. Epub 2009 Apr 16.

4.

The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes.

Panaghie G, Abbott GW.

J Gen Physiol. 2007 Feb;129(2):121-33. Epub 2007 Jan 16.

5.

Adult Ventricular Myocytes Segregate KCNQ1 and KCNE1 to Keep the IKs Amplitude in Check Until When Larger IKs Is Needed.

Jiang M, Wang Y, Tseng GN.

Circ Arrhythm Electrophysiol. 2017 Jun;10(6). pii: e005084. doi: 10.1161/CIRCEP.117.005084.

6.

Interaction of KCNE subunits with the KCNQ1 K+ channel pore.

Panaghie G, Tai KK, Abbott GW.

J Physiol. 2006 Feb 1;570(Pt 3):455-67. Epub 2005 Nov 24.

7.

[Ca2+]i elevation and oxidative stress induce KCNQ1 protein translocation from the cytosol to the cell surface and increase slow delayed rectifier (IKs) in cardiac myocytes.

Wang Y, Zankov DP, Jiang M, Zhang M, Henderson SC, Tseng GN.

J Biol Chem. 2013 Dec 6;288(49):35358-71. doi: 10.1074/jbc.M113.504746. Epub 2013 Oct 18.

8.

MinK: a double-hearted partner in cardiac repolarization.

van Ginneken AC.

Cardiovasc Res. 2009 Jun 1;82(3):390-1. doi: 10.1093/cvr/cvp112. Epub 2009 Apr 7. No abstract available.

PMID:
19351739
10.

BACE1 modulates gating of KCNQ1 (Kv7.1) and cardiac delayed rectifier KCNQ1/KCNE1 (IKs).

Agsten M, Hessler S, Lehnert S, Volk T, Rittger A, Hartmann S, Raab C, Kim DY, Groemer TW, Schwake M, Alzheimer C, Huth T.

J Mol Cell Cardiol. 2015 Dec;89(Pt B):335-48. doi: 10.1016/j.yjmcc.2015.10.006. Epub 2015 Oct 8.

PMID:
26454161
11.

LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.

Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM.

Cardiovasc Res. 2014 Dec 1;104(3):501-11. doi: 10.1093/cvr/cvu231. Epub 2014 Oct 24.

12.

Transcripts of Kv7.1 and MinK channels and slow delayed rectifier K+ current (IKs) are expressed in zebrafish (Danio rerio) heart.

Abramochkin DV, Hassinen M, Vornanen M.

Pflugers Arch. 2018 Dec;470(12):1753-1764. doi: 10.1007/s00424-018-2193-1. Epub 2018 Aug 16.

PMID:
30116893
13.

Protein kinase C epsilon mediates the inhibition of angiotensin II on the slowly activating delayed-rectifier potassium current through channel phosphorylation.

Gou X, Wang W, Zou S, Qi Y, Xu Y.

J Mol Cell Cardiol. 2018 Mar;116:165-174. doi: 10.1016/j.yjmcc.2018.02.010. Epub 2018 Feb 13.

PMID:
29452158
14.

Modulation of functional properties of KCNQ1 channel by association of KCNE1 and KCNE2.

Toyoda F, Ueyama H, Ding WG, Matsuura H.

Biochem Biophys Res Commun. 2006 Jun 9;344(3):814-20. Epub 2006 Apr 19.

PMID:
16631607
15.

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels.

Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M.

Proc Natl Acad Sci U S A. 2013 May 21;110(21):8732-7. doi: 10.1073/pnas.1300684110. Epub 2013 May 6.

16.

Long-QT mutation p.K557E-Kv7.1: dominant-negative suppression of IKs, but preserved cAMP-dependent up-regulation.

Spätjens RL, Bébarová M, Seyen SR, Lentink V, Jongbloed RJ, Arens YH, Heijman J, Volders PG.

Cardiovasc Res. 2014 Oct 1;104(1):216-25. doi: 10.1093/cvr/cvu191. Epub 2014 Aug 18.

PMID:
25139741
17.

Rb+ efflux through functional activation of cardiac KCNQ1/minK channels by the benzodiazepine R-L3 (L-364,373).

Jow F, Tseng E, Maddox T, Shen R, Kowal D, Dunlop J, Mekonnen B, Wang K.

Assay Drug Dev Technol. 2006 Aug;4(4):443-50.

PMID:
16945016
18.

SUMOylation determines the voltage required to activate cardiac IKs channels.

Xiong D, Li T, Dai H, Arena AF, Plant LD, Goldstein SAN.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6686-E6694. doi: 10.1073/pnas.1706267114. Epub 2017 Jul 25.

19.
20.

IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules.

Nicolas CS, Park KH, El Harchi A, Camonis J, Kass RS, Escande D, Mérot J, Loussouarn G, Le Bouffant F, Baró I.

Cardiovasc Res. 2008 Aug 1;79(3):427-35. doi: 10.1093/cvr/cvn085. Epub 2008 Apr 5.

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