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Items: 1 to 20 of 266

1.

Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice.

Cheng HL, Vuong BQ, Basu U, Franklin A, Schwer B, Astarita J, Phan RT, Datta A, Manis J, Alt FW, Chaudhuri J.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2717-22. doi: 10.1073/pnas.0812304106. Epub 2009 Feb 5. Erratum in: Proc Natl Acad Sci U S A. 2013 Apr 2;110(14):5731.

2.

Role of activation-induced deaminase protein kinase A phosphorylation sites in Ig gene conversion and somatic hypermutation.

Chatterji M, Unniraman S, McBride KM, Schatz DG.

J Immunol. 2007 Oct 15;179(8):5274-80.

3.

The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation.

Basu U, Chaudhuri J, Alpert C, Dutt S, Ranganath S, Li G, Schrum JP, Manis JP, Alt FW.

Nature. 2005 Nov 24;438(7067):508-11. Epub 2005 Oct 26.

PMID:
16251902
4.

Evolution of phosphorylation-dependent regulation of activation-induced cytidine deaminase.

Basu U, Wang Y, Alt FW.

Mol Cell. 2008 Oct 24;32(2):285-91. doi: 10.1016/j.molcel.2008.08.019.

5.

The C-terminal region of activation-induced cytidine deaminase is responsible for a recombination function other than DNA cleavage in class switch recombination.

Doi T, Kato L, Ito S, Shinkura R, Wei M, Nagaoka H, Wang J, Honjo T.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2758-63. doi: 10.1073/pnas.0813253106. Epub 2009 Feb 6.

7.

HoxC4 binds to the promoter of the cytidine deaminase AID gene to induce AID expression, class-switch DNA recombination and somatic hypermutation.

Park SR, Zan H, Pal Z, Zhang J, Al-Qahtani A, Pone EJ, Xu Z, Mai T, Casali P.

Nat Immunol. 2009 May;10(5):540-50. doi: 10.1038/ni.1725. Epub 2009 Apr 12.

8.

Regulation of activation induced deaminase via phosphorylation.

Basu U, Chaudhuri J, Phan RT, Datta A, Alt FW.

Adv Exp Med Biol. 2007;596:129-37. Review.

PMID:
17338181
9.

Regulation of class switch recombination and somatic mutation by AID phosphorylation.

McBride KM, Gazumyan A, Woo EM, Schwickert TA, Chait BT, Nussenzweig MC.

J Exp Med. 2008 Oct 27;205(11):2585-94. doi: 10.1084/jem.20081319. Epub 2008 Oct 6.

10.

Evolution of the immunoglobulin heavy chain class switch recombination mechanism.

Chaudhuri J, Basu U, Zarrin A, Yan C, Franco S, Perlot T, Vuong B, Wang J, Phan RT, Datta A, Manis J, Alt FW.

Adv Immunol. 2007;94:157-214. Review.

PMID:
17560275
11.

AID dysregulation in lupus-prone MRL/Fas(lpr/lpr) mice increases class switch DNA recombination and promotes interchromosomal c-Myc/IgH loci translocations: modulation by HoxC4.

White CA, Seth Hawkins J, Pone EJ, Yu ES, Al-Qahtani A, Mai T, Zan H, Casali P.

Autoimmunity. 2011 Dec;44(8):585-98. doi: 10.3109/08916934.2011.577128. Epub 2011 May 18. Erratum in: Autoimmunity. 2011 Dec;44(8):664.

12.

Replication protein A interacts with AID to promote deamination of somatic hypermutation targets.

Chaudhuri J, Khuong C, Alt FW.

Nature. 2004 Aug 26;430(7003):992-8. Epub 2004 Jul 25.

14.

Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation.

McBride KM, Gazumyan A, Woo EM, Barreto VM, Robbiani DF, Chait BT, Nussenzweig MC.

Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8798-803. Epub 2006 May 24.

15.

Iron inhibits activation-induced cytidine deaminase enzymatic activity and modulates immunoglobulin class switch DNA recombination.

Li G, Pone EJ, Tran DC, Patel PJ, Dao L, Xu Z, Casali P.

J Biol Chem. 2012 Jun 15;287(25):21520-9. doi: 10.1074/jbc.M112.366732. Epub 2012 May 3.

16.

The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.

Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW.

Cell. 2011 Feb 4;144(3):353-63. doi: 10.1016/j.cell.2011.01.001. Epub 2011 Jan 20.

17.

Histone chaperone Spt6 is required for class switch recombination but not somatic hypermutation.

Okazaki IM, Okawa K, Kobayashi M, Yoshikawa K, Kawamoto S, Nagaoka H, Shinkura R, Kitawaki Y, Taniguchi H, Natsume T, Iemura S, Honjo T.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7920-5. doi: 10.1073/pnas.1104423108. Epub 2011 Apr 25.

18.

Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase.

Yousif AS, Stanlie A, Mondal S, Honjo T, Begum NA.

Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1016-24. doi: 10.1073/pnas.1402391111. Epub 2014 Mar 3.

19.

Separate domains of AID are required for somatic hypermutation and class-switch recombination.

Shinkura R, Ito S, Begum NA, Nagaoka H, Muramatsu M, Kinoshita K, Sakakibara Y, Hijikata H, Honjo T.

Nat Immunol. 2004 Jul;5(7):707-12. Epub 2004 Jun 13.

PMID:
15195091
20.

C-terminal region of activation-induced cytidine deaminase (AID) is required for efficient class switch recombination and gene conversion.

Sabouri S, Kobayashi M, Begum NA, Xu J, Hirota K, Honjo T.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2253-8. doi: 10.1073/pnas.1324057111. Epub 2014 Jan 27.

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