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Items: 1 to 20 of 96

1.

ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus [corrected].

Castle JC, Hara Y, Raymond CK, Garrett-Engele P, Ohwaki K, Kan Z, Kusunoki J, Johnson JM.

PLoS One. 2009;4(2):e4369. doi: 10.1371/journal.pone.0004369. Epub 2009 Feb 3. Erratum in: PLoS One. 2009; 4(2) doi:10.1371/annotation/c921dfce-9702-4632-abbe-f13d62fdfde0.

2.

Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms.

Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ.

J Biol Chem. 1997 Apr 18;272(16):10669-77.

3.

Acetyl-CoA carboxylases 1 and 2 show distinct expression patterns in rats and humans and alterations in obesity and diabetes.

Kreuz S, Schoelch C, Thomas L, Rist W, Rippmann JF, Neubauer H.

Diabetes Metab Res Rev. 2009 Sep;25(6):577-86. doi: 10.1002/dmrr.997.

PMID:
19618481
4.

Expression, purification, and characterization of human acetyl-CoA carboxylase 2.

Kim KW, Yamane H, Zondlo J, Busby J, Wang M.

Protein Expr Purif. 2007 May;53(1):16-23. Epub 2006 Dec 9.

PMID:
17223360
5.

Hepatic de novo lipogenesis is present in liver-specific ACC1-deficient mice.

Harada N, Oda Z, Hara Y, Fujinami K, Okawa M, Ohbuchi K, Yonemoto M, Ikeda Y, Ohwaki K, Aragane K, Tamai Y, Kusunoki J.

Mol Cell Biol. 2007 Mar;27(5):1881-8. Epub 2007 Jan 8. Erratum in: Mol Cell Biol. 2007 May;27(9):3556.

6.

Isozyme-nonselective N-substituted bipiperidylcarboxamide acetyl-CoA carboxylase inhibitors reduce tissue malonyl-CoA concentrations, inhibit fatty acid synthesis, and increase fatty acid oxidation in cultured cells and in experimental animals.

Harwood HJ Jr, Petras SF, Shelly LD, Zaccaro LM, Perry DA, Makowski MR, Hargrove DM, Martin KA, Tracey WR, Chapman JG, Magee WP, Dalvie DK, Soliman VF, Martin WH, Mularski CJ, Eisenbeis SA.

J Biol Chem. 2003 Sep 26;278(39):37099-111. Epub 2003 Jul 3.

7.

The regulation of acetyl-CoA carboxylase--a potential target for the action of hypolipidemic agents.

Munday MR, Hemingway CJ.

Adv Enzyme Regul. 1999;39:205-34. Review.

PMID:
10470374
8.

Hormonal regulation of acetyl-CoA carboxylase isoenzyme gene transcription.

Zhao LF, Iwasaki Y, Zhe W, Nishiyama M, Taguchi T, Tsugita M, Kambayashi M, Hashimoto K, Terada Y.

Endocr J. 2010;57(4):317-24. Epub 2010 Feb 7.

9.

Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal.

Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z, Wakil SJ.

Proc Natl Acad Sci U S A. 2005 Aug 23;102(34):12011-6. Epub 2005 Aug 15.

10.

Molecular characterization and tissue-specific expression of the acetyl-CoA carboxylase α gene from Grass carp, Ctenopharyngodon idella.

Cheng HL, Ji NJ, Peng YX, Shen X, Xu JH, Dong ZG, Wu CC.

Gene. 2011 Nov 1;487(1):46-51. doi: 10.1016/j.gene.2011.07.027. Epub 2011 Aug 2.

PMID:
21839155
11.

The subcellular localization of acetyl-CoA carboxylase 2.

Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G, Wakil SJ.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1444-9.

12.

Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism.

Hasslacher M, Ivessa AS, Paltauf F, Kohlwein SD.

J Biol Chem. 1993 May 25;268(15):10946-52.

13.

Expression of genes regulating malonyl-CoA in human skeletal muscle.

Pender C, Trentadue AR, Pories WJ, Dohm GL, Houmard JA, Youngren JF.

J Cell Biochem. 2006 Oct 15;99(3):860-7.

PMID:
16721829
14.

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2.

Abu-Elheiga L, Matzuk MM, Abo-Hashema KA, Wakil SJ.

Science. 2001 Mar 30;291(5513):2613-6.

15.

Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis.

Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, Kordari P, Chirala SS, Heird WC, Wakil SJ.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8552-7. Epub 2006 May 22.

16.

Acetyl-CoA carboxylase-a as a novel target for cancer therapy.

Wang C, Rajput S, Watabe K, Liao DF, Cao D.

Front Biosci (Schol Ed). 2010 Jan 1;2:515-26. Review.

PMID:
20036965
17.

Differential activation of recombinant human acetyl-CoA carboxylases 1 and 2 by citrate.

Locke GA, Cheng D, Witmer MR, Tamura JK, Haque T, Carney RF, Rendina AR, Marcinkeviciene J.

Arch Biochem Biophys. 2008 Jul 1;475(1):72-9. doi: 10.1016/j.abb.2008.04.011. Epub 2008 Apr 18.

PMID:
18455495
19.

Synthesis and structure-activity relationships of N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1- methylprop-2-ynyl}carboxy derivatives as selective acetyl-CoA carboxylase 2 inhibitors.

Gu YG, Weitzberg M, Clark RF, Xu X, Li Q, Zhang T, Hansen TM, Liu G, Xin Z, Wang X, Wang R, McNally T, Zinker BA, Frevert EU, Camp HS, Beutel BA, Sham HL.

J Med Chem. 2006 Jun 29;49(13):3770-3. Erratum in: J Med Chem. 2006 Aug 10;49(16):5028. Zinker, Bradley A [added]; Frevert, Ernst U [added]; Camp, Heidi [corrected to Camp, Heidi S].

PMID:
16789734
20.

Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2.

Savage DB, Choi CS, Samuel VT, Liu ZX, Zhang D, Wang A, Zhang XM, Cline GW, Yu XX, Geisler JG, Bhanot S, Monia BP, Shulman GI.

J Clin Invest. 2006 Mar;116(3):817-24. Epub 2006 Feb 16.

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