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Items: 1 to 20 of 96

1.

Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature.

Charafe-Jauffret E, Ginestier C, Iovino F, Wicinski J, Cervera N, Finetti P, Hur MH, Diebel ME, Monville F, Dutcher J, Brown M, Viens P, Xerri L, Bertucci F, Stassi G, Dontu G, Birnbaum D, Wicha MS.

Cancer Res. 2009 Feb 15;69(4):1302-13. doi: 10.1158/0008-5472.CAN-08-2741. Epub 2009 Feb 3.

2.

Aldehyde dehydrogenase activity of breast cancer stem cells is primarily due to isoform ALDH1A3 and its expression is predictive of metastasis.

Marcato P, Dean CA, Pan D, Araslanova R, Gillis M, Joshi M, Helyer L, Pan L, Leidal A, Gujar S, Giacomantonio CA, Lee PW.

Stem Cells. 2011 Jan;29(1):32-45. doi: 10.1002/stem.563.

3.

The expression of stem cell protein Piwil2 and piR-932 in breast cancer.

Zhang H, Ren Y, Xu H, Pang D, Duan C, Liu C.

Surg Oncol. 2013 Dec;22(4):217-23. doi: 10.1016/j.suronc.2013.07.001. Epub 2013 Aug 27.

PMID:
23992744
4.

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer.

Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, Esterni B, Houvenaeghel G, Extra JM, Bertucci F, Jacquemier J, Xerri L, Dontu G, Stassi G, Xiao Y, Barsky SH, Birnbaum D, Viens P, Wicha MS.

Clin Cancer Res. 2010 Jan 1;16(1):45-55. doi: 10.1158/1078-0432.CCR-09-1630. Epub 2009 Dec 22.

5.

Phenotypic characterization of mammosphere-forming cells from the human MA-11 breast carcinoma cell line.

Rappa G, Lorico A.

Exp Cell Res. 2010 May 15;316(9):1576-86. doi: 10.1016/j.yexcr.2010.01.012. Epub 2010 Jan 11.

6.

Essential role of aldehyde dehydrogenase 1A3 for the maintenance of non-small cell lung cancer stem cells is associated with the STAT3 pathway.

Shao C, Sullivan JP, Girard L, Augustyn A, Yenerall P, Rodriguez-Canales J, Liu H, Behrens C, Shay JW, Wistuba II, Minna JD.

Clin Cancer Res. 2014 Aug 1;20(15):4154-66. doi: 10.1158/1078-0432.CCR-13-3292. Epub 2014 Jun 6.

7.

HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion.

Korkaya H, Paulson A, Iovino F, Wicha MS.

Oncogene. 2008 Oct 16;27(47):6120-30. doi: 10.1038/onc.2008.207. Epub 2008 Jun 30.

8.

Gene expression profiles of prostate cancer stem cells isolated by aldehyde dehydrogenase activity assay.

Nishida S, Hirohashi Y, Torigoe T, Kitamura H, Takahashi A, Masumori N, Tsukamoto T, Sato N.

J Urol. 2012 Jul;188(1):294-9. doi: 10.1016/j.juro.2012.02.2555. Epub 2012 May 16.

PMID:
22608744
9.

CXCR1 blockade selectively targets human breast cancer stem cells in vitro and in xenografts.

Ginestier C, Liu S, Diebel ME, Korkaya H, Luo M, Brown M, Wicinski J, Cabaud O, Charafe-Jauffret E, Birnbaum D, Guan JL, Dontu G, Wicha MS.

J Clin Invest. 2010 Feb;120(2):485-97. doi: 10.1172/JCI39397. Epub 2010 Jan 4.

10.

Single-cell analysis reveals a stem-cell program in human metastatic breast cancer cells.

Lawson DA, Bhakta NR, Kessenbrock K, Prummel KD, Yu Y, Takai K, Zhou A, Eyob H, Balakrishnan S, Wang CY, Yaswen P, Goga A, Werb Z.

Nature. 2015 Oct 1;526(7571):131-5. doi: 10.1038/nature15260. Epub 2015 Sep 23.

11.

Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells.

Lin JJ, Huang CS, Yu J, Liao GS, Lien HC, Hung JT, Lin RJ, Chou FP, Yeh KT, Yu AL.

Breast Cancer Res. 2014 Mar 26;16(2):R29. doi: 10.1186/bcr3631.

12.

Breast cancer stem-like cells are inhibited by a non-toxic aryl hydrocarbon receptor agonist.

Prud'homme GJ, Glinka Y, Toulina A, Ace O, Subramaniam V, Jothy S.

PLoS One. 2010 Nov 3;5(11):e13831. doi: 10.1371/journal.pone.0013831.

13.

Oestrogen increases the activity of oestrogen receptor negative breast cancer stem cells through paracrine EGFR and Notch signalling.

Harrison H, Simões BM, Rogerson L, Howell SJ, Landberg G, Clarke RB.

Breast Cancer Res. 2013 Mar 8;15(2):R21. doi: 10.1186/bcr3396.

14.

Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation.

Louie E, Nik S, Chen JS, Schmidt M, Song B, Pacson C, Chen XF, Park S, Ju J, Chen EI.

Breast Cancer Res. 2010;12(6):R94. doi: 10.1186/bcr2773. Epub 2010 Nov 10.

15.

Tumor initiating but differentiated luminal-like breast cancer cells are highly invasive in the absence of basal-like activity.

Kim J, Villadsen R, Sørlie T, Fogh L, Grønlund SZ, Fridriksdottir AJ, Kuhn I, Rank F, Wielenga VT, Solvang H, Edwards PA, Børresen-Dale AL, Rønnov-Jessen L, Bissell MJ, Petersen OW.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6124-9. doi: 10.1073/pnas.1203203109. Epub 2012 Mar 27.

16.

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.

Croker AK, Goodale D, Chu J, Postenka C, Hedley BD, Hess DA, Allan AL.

J Cell Mol Med. 2009 Aug;13(8B):2236-52. doi: 10.1111/j.1582-4934.2008.00455.x. Epub 2008 Aug 4.

17.

Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.

Li Y, Zhang T, Korkaya H, Liu S, Lee HF, Newman B, Yu Y, Clouthier SG, Schwartz SJ, Wicha MS, Sun D.

Clin Cancer Res. 2010 May 1;16(9):2580-90. doi: 10.1158/1078-0432.CCR-09-2937. Epub 2010 Apr 13.

18.

Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.

Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.

Biochem Biophys Res Commun. 2013 Sep 13;439(1):96-102. doi: 10.1016/j.bbrc.2013.08.021. Epub 2013 Aug 13.

PMID:
23954638
19.

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.

Farnie G, Sotgia F, Lisanti MP.

Oncotarget. 2015 Oct 13;6(31):30472-86. doi: 10.18632/oncotarget.5401.

20.

ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program.

Charafe-Jauffret E, Ginestier C, Bertucci F, Cabaud O, Wicinski J, Finetti P, Josselin E, Adelaide J, Nguyen TT, Monville F, Jacquemier J, Thomassin-Piana J, Pinna G, Jalaguier A, Lambaudie E, Houvenaeghel G, Xerri L, Harel-Bellan A, Chaffanet M, Viens P, Birnbaum D.

Cancer Res. 2013 Dec 15;73(24):7290-300. doi: 10.1158/0008-5472.CAN-12-4704. Epub 2013 Oct 18.

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