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Items: 1 to 20 of 173

1.

The SCF Slimb ubiquitin ligase regulates Plk4/Sak levels to block centriole reduplication.

Rogers GC, Rusan NM, Roberts DM, Peifer M, Rogers SL.

J Cell Biol. 2009 Jan 26;184(2):225-39. doi: 10.1083/jcb.200808049.

2.

The SCF/Slimb ubiquitin ligase limits centrosome amplification through degradation of SAK/PLK4.

Cunha-Ferreira I, Rodrigues-Martins A, Bento I, Riparbelli M, Zhang W, Laue E, Callaini G, Glover DM, Bettencourt-Dias M.

Curr Biol. 2009 Jan 13;19(1):43-9. doi: 10.1016/j.cub.2008.11.037. Epub 2008 Dec 11.

3.

Polo-like kinase 4 autodestructs by generating its Slimb-binding phosphodegron.

Klebba JE, Buster DW, Nguyen AL, Swatkoski S, Gucek M, Rusan NM, Rogers GC.

Curr Biol. 2013 Nov 18;23(22):2255-61. doi: 10.1016/j.cub.2013.09.019. Epub 2013 Oct 31.

4.

Regulation of autophosphorylation controls PLK4 self-destruction and centriole number.

Cunha-Ferreira I, Bento I, Pimenta-Marques A, Jana SC, Lince-Faria M, Duarte P, Borrego-Pinto J, Gilberto S, Amado T, Brito D, Rodrigues-Martins A, Debski J, Dzhindzhev N, Bettencourt-Dias M.

Curr Biol. 2013 Nov 18;23(22):2245-54. doi: 10.1016/j.cub.2013.09.037. Epub 2013 Oct 31.

5.

Asterless Reduction during Spermiogenesis Is Regulated by Plk4 and Is Essential for Zygote Development in Drosophila.

Khire A, Vizuet AA, Davila E, Avidor-Reiss T.

Curr Biol. 2015 Nov 16;25(22):2956-63. doi: 10.1016/j.cub.2015.09.045. Epub 2015 Oct 17.

6.

The C. elegans F-box proteins LIN-23 and SEL-10 antagonize centrosome duplication by regulating ZYG-1 levels.

Peel N, Dougherty M, Goeres J, Liu Y, O'Connell KF.

J Cell Sci. 2012 Aug 1;125(Pt 15):3535-44. Epub 2012 May 23.

7.

Cullin 1 functions as a centrosomal suppressor of centriole multiplication by regulating polo-like kinase 4 protein levels.

Korzeniewski N, Zheng L, Cuevas R, Parry J, Chatterjee P, Anderton B, Duensing A, Münger K, Duensing S.

Cancer Res. 2009 Aug 15;69(16):6668-75. doi: 10.1158/0008-5472.CAN-09-1284.

8.

The E3 ubiquitin ligase Mib1 regulates Plk4 and centriole biogenesis.

Čajánek L, Glatter T, Nigg EA.

J Cell Sci. 2015 May 1;128(9):1674-82. doi: 10.1242/jcs.166496. Epub 2015 Mar 20.

9.

Cep152 interacts with Plk4 and is required for centriole duplication.

Hatch EM, Kulukian A, Holland AJ, Cleveland DW, Stearns T.

J Cell Biol. 2010 Nov 15;191(4):721-9. doi: 10.1083/jcb.201006049. Epub 2010 Nov 8.

10.
11.

Components of an SCF ubiquitin ligase localize to the centrosome and regulate the centrosome duplication cycle.

Freed E, Lacey KR, Huie P, Lyapina SA, Deshaies RJ, Stearns T, Jackson PK.

Genes Dev. 1999 Sep 1;13(17):2242-57.

12.

The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication.

Puklowski A, Homsi Y, Keller D, May M, Chauhan S, Kossatz U, Grünwald V, Kubicka S, Pich A, Manns MP, Hoffmann I, Gönczy P, Malek NP.

Nat Cell Biol. 2011 Jul 3;13(8):1004-9. doi: 10.1038/ncb2282.

PMID:
21725316
13.

Two Polo-like kinase 4 binding domains in Asterless perform distinct roles in regulating kinase stability.

Klebba JE, Galletta BJ, Nye J, Plevock KM, Buster DW, Hollingsworth NA, Slep KC, Rusan NM, Rogers GC.

J Cell Biol. 2015 Feb 16;208(4):401-14. doi: 10.1083/jcb.201410105.

14.

Human Cep192 and Cep152 cooperate in Plk4 recruitment and centriole duplication.

Sonnen KF, Gabryjonczyk AM, Anselm E, Stierhof YD, Nigg EA.

J Cell Sci. 2013 Jul 15;126(Pt 14):3223-33. doi: 10.1242/jcs.129502. Epub 2013 May 2.

15.

A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning.

Wong JJ, Li S, Lim EK, Wang Y, Wang C, Zhang H, Kirilly D, Wu C, Liou YC, Wang H, Yu F.

PLoS Biol. 2013 Sep;11(9):e1001657. doi: 10.1371/journal.pbio.1001657. Epub 2013 Sep 17.

16.

Crumbs promotes expanded recognition and degradation by the SCF(Slimb/β-TrCP) ubiquitin ligase.

Ribeiro P, Holder M, Frith D, Snijders AP, Tapon N.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1980-9. doi: 10.1073/pnas.1315508111. Epub 2014 Apr 28.

17.

The SCF ubiquitin ligase protein slimb regulates centrosome duplication in Drosophila.

Wojcik EJ, Glover DM, Hays TS.

Curr Biol. 2000 Sep 21;10(18):1131-4.

18.

The Protein Phosphatase 2A regulatory subunit Twins stabilizes Plk4 to induce centriole amplification.

Brownlee CW, Klebba JE, Buster DW, Rogers GC.

J Cell Biol. 2011 Oct 17;195(2):231-43. doi: 10.1083/jcb.201107086. Epub 2011 Oct 10.

19.

Asterless is a scaffold for the onset of centriole assembly.

Dzhindzhev NS, Yu QD, Weiskopf K, Tzolovsky G, Cunha-Ferreira I, Riparbelli M, Rodrigues-Martins A, Bettencourt-Dias M, Callaini G, Glover DM.

Nature. 2010 Oct 7;467(7316):714-8. doi: 10.1038/nature09445. Epub 2010 Sep 19.

PMID:
20852615
20.

The SCFSlimb E3 ligase complex regulates asymmetric division to inhibit neuroblast overgrowth.

Li S, Wang C, Sandanaraj E, Aw SS, Koe CT, Wong JJ, Yu F, Ang BT, Tang C, Wang H.

EMBO Rep. 2014 Feb;15(2):165-74. doi: 10.1002/embr.201337966. Epub 2014 Jan 10.

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