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Export of RNA silencing from C. elegans tissues does not require the RNA channel SID-1.

Jose AM, Smith JJ, Hunter CP.

Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2283-8. doi: 10.1073/pnas.0809760106. Epub 2009 Jan 23.


Caenorhabditis elegans SID-2 is required for environmental RNA interference.

Winston WM, Sutherlin M, Wright AJ, Feinberg EH, Hunter CP.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10565-70. Epub 2007 Jun 11.


SID-5 is an endosome-associated protein required for efficient systemic RNAi in C. elegans.

Hinas A, Wright AJ, Hunter CP.

Curr Biol. 2012 Oct 23;22(20):1938-43. doi: 10.1016/j.cub.2012.08.020. Epub 2012 Sep 13.


SID-1 is a dsRNA-selective dsRNA-gated channel.

Shih JD, Hunter CP.

RNA. 2011 Jun;17(6):1057-65. doi: 10.1261/rna.2596511. Epub 2011 Apr 7.


Systemic RNA Interference Deficiency-1 (SID-1) Extracellular Domain Selectively Binds Long Double-stranded RNA and Is Required for RNA Transport by SID-1.

Li W, Koutmou KS, Leahy DJ, Li M.

J Biol Chem. 2015 Jul 31;290(31):18904-13. doi: 10.1074/jbc.M115.658864. Epub 2015 Jun 11.


The SID-1 double-stranded RNA transporter is not selective for dsRNA length.

Shih JD, Fitzgerald MC, Sutherlin M, Hunter CP.

RNA. 2009 Mar;15(3):384-90. doi: 10.1261/rna.1286409. Epub 2009 Jan 20.


The double-stranded RNA binding protein RDE-4 can act cell autonomously during feeding RNAi in C. elegans.

Raman P, Zaghab SM, Traver EC, Jose AM.

Nucleic Acids Res. 2017 Aug 21;45(14):8463-8473. doi: 10.1093/nar/gkx484.


Uptake of extracellular double-stranded RNA by SID-2.

McEwan DL, Weisman AS, Hunter CP.

Mol Cell. 2012 Sep 14;47(5):746-54. doi: 10.1016/j.molcel.2012.07.014. Epub 2012 Aug 16.


Systemic RNAi in C. elegans requires the putative transmembrane protein SID-1.

Winston WM, Molodowitch C, Hunter CP.

Science. 2002 Mar 29;295(5564):2456-9. Epub 2002 Feb 7.


Systemic RNAi in Caenorhabditis elegans.

Hunter CP, Winston WM, Molodowitch C, Feinberg EH, Shih J, Sutherlin M, Wright AJ, Fitzgerald MC.

Cold Spring Harb Symp Quant Biol. 2006;71:95-100. Review.


Conserved tyrosine kinase promotes the import of silencing RNA into Caenorhabditis elegans cells.

Jose AM, Kim YA, Leal-Ekman S, Hunter CP.

Proc Natl Acad Sci U S A. 2012 Sep 4;109(36):14520-5. doi: 10.1073/pnas.1201153109. Epub 2012 Aug 21.


Two classes of silencing RNAs move between Caenorhabditis elegans tissues.

Jose AM, Garcia GA, Hunter CP.

Nat Struct Mol Biol. 2011 Oct 9;18(11):1184-8. doi: 10.1038/nsmb.2134.


Enhanced neuronal RNAi in C. elegans using SID-1.

Calixto A, Chelur D, Topalidou I, Chen X, Chalfie M.

Nat Methods. 2010 Jul;7(7):554-9. doi: 10.1038/nmeth.1463. Epub 2010 May 30.


In C. elegans, high levels of dsRNA allow RNAi in the absence of RDE-4.

Habig JW, Aruscavage PJ, Bass BL.

PLoS One. 2008;3(12):e4052. doi: 10.1371/journal.pone.0004052. Epub 2008 Dec 29.


SID-1 protein of Caenorhabditis elegans mediates uptake of dsRNA into Bombyx cells.

Kobayashi I, Tsukioka H, K├┤moto N, Uchino K, Sezutsu H, Tamura T, Kusakabe T, Tomita S.

Insect Biochem Mol Biol. 2012 Feb;42(2):148-54. doi: 10.1016/j.ibmb.2011.11.007. Epub 2011 Dec 8.


Transport of dsRNA into cells by the transmembrane protein SID-1.

Feinberg EH, Hunter CP.

Science. 2003 Sep 12;301(5639):1545-7.


The role of RNA editing by ADARs in RNAi.

Knight SW, Bass BL.

Mol Cell. 2002 Oct;10(4):809-17.


SID-1 Domains Important for dsRNA Import in Caenorhabditis elegans.

Whangbo JS, Weisman AS, Chae J, Hunter CP.

G3 (Bethesda). 2017 Dec 4;7(12):3887-3899. doi: 10.1534/g3.117.300308.


The conserved SNARE SEC-22 localizes to late endosomes and negatively regulates RNA interference in Caenorhabditis elegans.

Zhao Y, Holmgren BT, Hinas A.

RNA. 2017 Mar;23(3):297-307. doi: 10.1261/rna.058438.116. Epub 2016 Dec 14.


Functional genomic analysis of RNA interference in C. elegans.

Kim JK, Gabel HW, Kamath RS, Tewari M, Pasquinelli A, Rual JF, Kennedy S, Dybbs M, Bertin N, Kaplan JM, Vidal M, Ruvkun G.

Science. 2005 May 20;308(5725):1164-7. Epub 2005 Mar 24.

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