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Items: 1 to 20 of 206

1.

NNZ-2566: a Gly-Pro-Glu analogue with neuroprotective efficacy in a rat model of acute focal stroke.

Bickerdike MJ, Thomas GB, Batchelor DC, Sirimanne ES, Leong W, Lin H, Sieg F, Wen J, Brimble MA, Harris PW, Gluckman PD.

J Neurol Sci. 2009 Mar 15;278(1-2):85-90. doi: 10.1016/j.jns.2008.12.003. Epub 2009 Jan 20.

PMID:
19157421
2.

SB 234551 selective ET(A) receptor antagonism: perfusion/diffusion MRI used to define treatable stroke model, time to treatment and mechanism of protection.

Legos JJ, Lenhard SC, Haimbach RE, Schaeffer TR, Bentley RG, McVey MJ, Chandra S, Irving EA, Andrew A Parsons, Barone FC.

Exp Neurol. 2008 Jul;212(1):53-62. doi: 10.1016/j.expneurol.2008.03.011. Epub 2008 Mar 25.

PMID:
18462720
3.

NNZ-2566, a glypromate analog, improves functional recovery and attenuates apoptosis and inflammation in a rat model of penetrating ballistic-type brain injury.

Lu XC, Chen RW, Yao C, Wei H, Yang X, Liao Z, Dave JR, Tortella FC.

J Neurotrauma. 2009 Jan;26(1):141-54. doi: 10.1089/neu.2008.0629.

PMID:
19119917
4.

Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats.

Guan J, Mathai S, Harris P, Wen JY, Zhang R, Brimble M, Gluckman P.

Neuropharmacology. 2007 Nov;53(6):749-62. Epub 2007 Aug 19.

PMID:
17904590
5.

NNZ-2566, a glypromate analog, attenuates brain ischemia-induced non-convulsive seizures in rats.

Lu XC, Si Y, Williams AJ, Hartings JA, Gryder D, Tortella FC.

J Cereb Blood Flow Metab. 2009 Dec;29(12):1924-32. doi: 10.1038/jcbfm.2009.109. Epub 2009 Jul 29.

PMID:
19638995
6.

NNZ-2566 treatment inhibits neuroinflammation and pro-inflammatory cytokine expression induced by experimental penetrating ballistic-like brain injury in rats.

Wei HH, Lu XC, Shear DA, Waghray A, Yao C, Tortella FC, Dave JR.

J Neuroinflammation. 2009 Aug 5;6:19. doi: 10.1186/1742-2094-6-19.

7.
8.

Neuroprotective effects of KCL-440, a new poly(ADP-ribose) polymerase inhibitor, in the rat middle cerebral artery occlusion model.

Ikeda Y, Hokamura K, Kawai T, Ishiyama J, Ishikawa K, Anraku T, Uno T, Umemura K.

Brain Res. 2005 Oct 26;1060(1-2):73-80. Epub 2005 Oct 3.

PMID:
16202986
9.
10.
11.

Delayed peripheral administration of a GPE analogue induces astrogliosis and angiogenesis and reduces inflammation and brain injury following hypoxia-ischemia in the neonatal rat.

Svedin P, Guan J, Mathai S, Zhang R, Wang X, Gustavsson M, Hagberg H, Mallard C.

Dev Neurosci. 2007;29(4-5):393-402.

PMID:
17762207
12.

Delayed post ischemic treatment with Rosiglitazone attenuates infarct volume, neurological deficits and neutrophilia after embolic stroke in rat.

Allahtavakoli M, Moloudi R, Arababadi MK, Shamsizadeh A, Javanmardi K.

Brain Res. 2009 May 19;1271:121-7. doi: 10.1016/j.brainres.2009.03.040. Epub 2009 Mar 28.

PMID:
19332033
13.

Glial growth factor 2 promotes functional recovery with treatment initiated up to 7 days after permanent focal ischemic stroke.

Iaci JF, Ganguly A, Finklestein SP, Parry TJ, Ren J, Saha S, Sietsma DK, Srinivas M, Vecchione AM, Caggiano AO.

Neuropharmacology. 2010 Dec;59(7-8):640-9. doi: 10.1016/j.neuropharm.2010.07.017. Epub 2010 Aug 4.

PMID:
20691195
14.
15.

Tanshinone IIB, a primary active constituent from Salvia miltiorrhza, exhibits neuro-protective activity in experimentally stroked rats.

Yu XY, Lin SG, Zhou ZW, Chen X, Liang J, Duan W, Yu XQ, Wen JY, Chowbay B, Li CG, Sheu FS, Chan E, Zhou SF.

Neurosci Lett. 2007 May 7;417(3):261-5. Epub 2007 Mar 12.

PMID:
17397998
16.

Mechanism of action for NNZ-2566 anti-inflammatory effects following PBBI involves upregulation of immunomodulator ATF3.

Cartagena CM, Phillips KL, Williams GL, Konopko M, Tortella FC, Dave JR, Schmid KE.

Neuromolecular Med. 2013 Sep;15(3):504-14. doi: 10.1007/s12017-013-8236-z. Epub 2013 Jun 14.

PMID:
23765588
17.

In vitro and in vivo neuroprotective effect and mechanisms of glabridin, a major active isoflavan from Glycyrrhiza glabra (licorice).

Yu XQ, Xue CC, Zhou ZW, Li CG, Du YM, Liang J, Zhou SF.

Life Sci. 2008 Jan 2;82(1-2):68-78. Epub 2007 Nov 7.

PMID:
18048062
18.

Selective antagonism of endothelin-A-receptors improves outcome in both head trauma and focal stroke in rat.

Barone FC, Ohlstein EH, Hunter AJ, Campbell CA, Hadingham SH, Parsons AA, Yang Y, Shohami E.

J Cardiovasc Pharmacol. 2000 Nov;36(5 Suppl 1):S357-61.

PMID:
11078420
19.

Neuroprotective effect of DAHK peptide in an occlusive model of permanent focal ischemia in rats.

Díaz-Ruíz A, Ríos C, Carvajal-Sotelo J, Ortiz-Plata A, Espino-Solis GP, Méndez-Armenta M, Montes S, Monroy-Noyola A.

Neurochem Res. 2010 Feb;35(2):343-7. doi: 10.1007/s11064-009-0060-3. Epub 2009 Sep 24.

PMID:
19777346
20.

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