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19154412,16723135,20647322,17516523,19654198,22151736,15223062,22030472,19889459,18840303,19836302,15904464,28724766,21332943,11807819,23475215,14574331,11237801,24389072,17015761,2146511,26550829,7772727,15147371,14729650,9357968,21219540,12870125,7774883,22763862,29845702,15449906,16014972,15788694,26077361,23733874,18808681,15161436,15157363,18477226,11186302,16532031,9770420,11159527,16235837,15181578,7690819,19657093,15129647,33410215,17230416,11485622,11302729,1630039,16388491,16146533,28011931,17457906,21509627,15494269,17875523,16778109,21402546,18027201,17223152,33524072,30666755,12910250,16155605,17051489,8638605,15332282,8152305,23888327,10438066,25703103,12854182,21208912,11971181,20219542,2786375,25612920,16242045,15551352,19951176,10233407,31438973,9808547,16308315,16943297,11000233,27893842,19188090,2794753,21704832,19453978,29444188,10551737,17935163,28035765,1449245,15871724,17205512,26289727,3264588,8895686,15147354,32453758,26063164,8246453,11601202,16805820,36081501,11027480,19165640,17900259,1373677,32311478,18071306,7959369,18830259,27105228,15047798,10942623,2532262,21244576,8101138,8728941,15747250,15478065,32918495,1373197,12072501,11342446,28866351,18178833,26251144,26134467,11861261,19206063,8820984,9137687,12073776,15289015,18639344,6152761,17140451,15692773,16076945,15569983,1418377,1767511,2795893,27795529,30787019,35315593,22111594,22507774,8874198,21205081,16512894,17258259,10025895,18552504,20525891,16052518,17233845,15846376,34073995,34907908,12032888,11861837,16603536,8763995,17006333,15225370,16474078,24196073,27250643,16110759,17384582,1984476,22735080,16585963,2593243,9026591,17083040,1660325,3180135,14603340,17133550,16155611,16112347,12584320,25281470,25320371,19751276,9820553,17086610,19570078,16883437,8411653,27795537,17973821,17715223,8245871,21800110,11080819,22453915,7512153,26296091,16897651,36177005,18300056,16155610,17352246,17962369,11505462,24416335,11426548,17950728,24727323,15854229,15882466,17523951,15679726,16048490,17255766,19386541,17588676,19374191,16540180,15771684,33771974,16271772,26316613,15656804,20219918,21720136,27776189,15930259,18027200,19493466,17620653,19447144,8691635,16091751,2179598,17696273,35687761,17886750,7537726,16912225,11426490,31642546,1355347,8801227,1996321,9835961,15743528,16042687,24791004,19578238,11468172,23349737,17765943,26381999,17237568,19264779,15617250,8449826,8130758,7668218,15329447,1540409,19159569,17028113,7496941,21483764,9215657,36730466,8366575,27034390,17487354,19400555,12685318,8502784,18346935,24739247,15621800,26745069,18712809,32009059,30652238,19152396,11734593,30914196,15753054,34685494,16740321,17884099,24316494,18173359,8416192,15727651,17622792,21645921,17479090,3000305,16155599,19245164,2786036,17587535,23538341,19694316,19306994,2492759,23383601,15902707,8152275,15149509,33798232,19261691,26631889,2630570,15964976,15739027,8797698,11404513,19490981,9973953,28978842,26666715,17929633,15292059,7760898,16271075,35458481,18339896,18516870,12857570,19290030,19242375,1547882,18577047,9426684,20591480,27210082,25590596,19099485,16256162,20976566,26981740,7938825,21044233,36181532,31344159,17696205,18094326,22969761,15692511,2696327,12637723,21909275,1289635,18377598,24724415,16061975,16925902,31616431,8811055,19134004,21969188,17183844,30562867,2971638,19533685,23464580,21311101,10835933,16630222,32196559,15619907,25840916,10322301,17977605,18455282,32952946,18456423,18023035,10632660,16534449,26696625,25604902,2116232,9851098,8496796,16628590,16155600,23289207,22973265,18031387,18558491,24434991,24628073,19076337,18691810,28340877,1849420,19136196,15370657,32793179,18689716,8389871,17923274,18081707,8468116,9672631,18842429,11963182,2585904,21971218,2903262,30032036,19047782,17284327,8165911,1421724,16555510,18544058,27169444,21792554,2809387,17028221,10708067,17102773,19018147,17951212,18692433,23962110,28811663,8100486,18814252,6607372,19037751,3243524,15770802,22730536,12353317,16440739,19143887,3018320,20432970,7474853,18954748,2502513,15632212,18992771,21971219,18477134,33091125,17976676,27215229,17132683,17448657,27651025,11984586,7727876,8603007,19115968,29615991,32367127,8826916,19106589,26693362,2741453,21720743,18355363,2593240,32884522,18377607,18680397,2787427,22191057,23292237,18302660,18623934,19151234,18980174,18941745,18637865,18544688,17994057,19599667[uid]

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Impaired Tax-specific T-cell responses with insufficient control of HTLV-1 in a subgroup of individuals at asymptomatic and smoldering stages.

Shimizu Y, Takamori A, Utsunomiya A, Kurimura M, Yamano Y, Hishizawa M, Hasegawa A, Kondo F, Kurihara K, Harashima N, Watanabe T, Okamura J, Masuda T, Kannagi M. Shimizu Y, et al. Cancer Sci. 2009 Mar;100(3):481-9. doi: 10.1111/j.1349-7006.2008.01054.x. Epub 2008 Dec 16. Cancer Sci. 2009. PMID: 19154412 Free article.

Human T-cell leukemia virus type-I (HTLV-I)-specific T-cell responses detected using three-divided glutathione-S-transferase (GST)-Tax fusion proteins.

Kurihara K, Shimizu Y, Takamori A, Harashima N, Noji M, Masuda T, Utsunomiya A, Okamura J, Kannagi M. Kurihara K, et al. J Immunol Methods. 2006 Jun 30;313(1-2):61-73. doi: 10.1016/j.jim.2006.03.013. Epub 2006 May 4. J Immunol Methods. 2006. PMID: 16723135

Single-cell analysis of T-cell receptor repertoire of HTLV-1 Tax-specific cytotoxic T cells in allogeneic transplant recipients with adult T-cell leukemia/lymphoma.

Tanaka Y, Nakasone H, Yamazaki R, Sato K, Sato M, Terasako K, Kimura S, Okuda S, Kako S, Oshima K, Tanihara A, Nishida J, Yoshikawa T, Nakatsura T, Sugiyama H, Kanda Y. Tanaka Y, et al. Cancer Res. 2010 Aug 1;70(15):6181-92. doi: 10.1158/0008-5472.CAN-10-0678. Epub 2010 Jul 20. Cancer Res. 2010. PMID: 20647322

Anti-HTLV-1 tax antibody and tax-specific cytotoxic T lymphocyte are associated with a reduction in HTLV-1 proviral load in asymptomatic carriers.

Akimoto M, Kozako T, Sawada T, Matsushita K, Ozaki A, Hamada H, Kawada H, Yoshimitsu M, Tokunaga M, Haraguchi K, Uozumi K, Arima N, Tei C. Akimoto M, et al. J Med Virol. 2007 Jul;79(7):977-86. doi: 10.1002/jmv.20807. J Med Virol. 2007. PMID: 17516523

Induction of IL-10- and IFN-gamma-producing T-cell responses by autoreactive T-cells expressing human T-cell leukemia virus type I Tax.

Takatsuka N, Hasegawa A, Takamori A, Shimizu Y, Kato H, Ohashi T, Amagasa T, Masuda T, Kannagi M. Takatsuka N, et al. Int Immunol. 2009 Sep;21(9):1089-100. doi: 10.1093/intimm/dxp074. Epub 2009 Aug 4. Int Immunol. 2009. PMID: 19654198

Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers.

Takamori A, Hasegawa A, Utsunomiya A, Maeda Y, Yamano Y, Masuda M, Shimizu Y, Tamai Y, Sasada A, Zeng N, Choi I, Uike N, Okamura J, Watanabe T, Masuda T, Kannagi M. Takamori A, et al. Retrovirology. 2011 Dec 7;8:100. doi: 10.1186/1742-4690-8-100. Retrovirology. 2011. PMID: 22151736 Free PMC article.

Immunological risks of adult T-cell leukemia at primary HTLV-I infection.

Kannagi M, Ohashi T, Harashima N, Hanabuchi S, Hasegawa A. Kannagi M, et al. Trends Microbiol. 2004 Jul;12(7):346-52. doi: 10.1016/j.tim.2004.05.005. Trends Microbiol. 2004. PMID: 15223062 Review.

Advantage of higher-avidity CTL specific for Tax against human T-lymphotropic virus-1 infected cells and tumors.

Kitazono T, Okazaki T, Araya N, Yamano Y, Yamada Y, Nakamura T, Tanaka Y, Inoue M, Ozaki S. Kitazono T, et al. Cell Immunol. 2011;272(1):11-7. doi: 10.1016/j.cellimm.2011.10.002. Epub 2011 Oct 8. Cell Immunol. 2011. PMID: 22030472

Efficient induction of human T-cell leukemia virus-1-specific CTL by chimeric particle without adjuvant as a prophylactic for adult T-cell leukemia.

Kozako T, Fukada K, Hirata S, White Y, Harao M, Nishimura Y, Kino Y, Soeda S, Shimeno H, Lemonnier F, Sonoda S, Arima N. Kozako T, et al. Mol Immunol. 2009 Dec;47(2-3):606-13. doi: 10.1016/j.molimm.2009.09.006. Epub 2009 Nov 3. Mol Immunol. 2009. PMID: 19889459

Activation and detection of HTLV-I Tax-specific CTLs by epitope expressing single-chain trimers of MHC class I in a rat model.

Ohashi T, Nagai M, Okada H, Takayanagi R, Shida H. Ohashi T, et al. Retrovirology. 2008 Oct 8;5:90. doi: 10.1186/1742-4690-5-90. Retrovirology. 2008. PMID: 18840303 Free PMC article.

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